| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.089454 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0423421 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0388922 |
| STC1 | stanniocalcin 1 | 0.037631 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0313646 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0296124 |
| NDRG1 | N-myc downstream regulated 1 | 0.0287775 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0287285 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0277076 |
| ATXN1 | ataxin 1 | 0.0248043 |
| TPM3 | tropomyosin 3 | 0.0235144 |
| MSN | moesin | 0.023133 |
| ANXA1 | annexin A1 | 0.022739 |
| PLEC | plectin | 0.0208922 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0204951 |
| RHOA | ras homolog family member A | 0.0194339 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0193937 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0193188 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0191736 |
| INTS6 | integrator complex subunit 6 | 0.0173685 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0171441 |
| INHBA | inhibin, beta A | 0.0167753 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0167621 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0165929 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0160783 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0159888 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0157647 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0150545 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0143697 |
| RHOB | ras homolog family member B | 0.0143109 |
| FLNA | filamin A, alpha | 0.014246 |
| RPL3 | ribosomal protein L3 | 0.0141929 |
| KALRN | kalirin, RhoGEF kinase | 0.0140714 |
| ATP13A3 | ATPase type 13A3 | 0.0139059 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0136325 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0135247 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.013161 |
| PYGL | phosphorylase, glycogen, liver | 0.01298 |
| AHNAK | AHNAK nucleoprotein | 0.012891 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0127063 |
| PRELID2 | PRELI domain containing 2 | 0.0125596 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0125541 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.012252 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0122119 |
| EMP3 | epithelial membrane protein 3 | 0.0116601 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0115331 |
| MEF2A | myocyte enhancer factor 2A | 0.0114954 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0111047 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.01107 |
| KLF6 | Kruppel-like factor 6 | 0.0110467 |
| PHF3 | PHD finger protein 3 | 0.0108175 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.010713 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.010589 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.010461 |
| MEAK7 | MTOR associated protein, eak-7 homolog | 0.0103689 |
| ACVR1 | activin A receptor, type I | 0.0103498 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0103484 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0103034 |
| OGA | O-GlcNAcase | 0.0102275 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0102067 |
| PCBP3 | poly(rC) binding protein 3 | 0.0101525 |
| CD109 | CD109 molecule | 0.0101375 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0100095 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0100082 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00977233 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.00970042 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0096863 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.00964107 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.00962156 |
| VCL | vinculin | 0.00961638 |
| STK10 | serine/threonine kinase 10 | 0.00959989 |
| SNX14 | sorting nexin 14 | 0.00955376 |
| SNX9 | sorting nexin 9 | 0.00953412 |
| ANK2 | ankyrin 2, neuronal | 0.00947219 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.00942869 |
| TMEM132B | transmembrane protein 132B | 0.00940955 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00933782 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0092604 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.00925644 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.00920043 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00918512 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00916848 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.00914499 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00902886 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00880513 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0087614 |
| MB21D2 | Mab-21 domain containing 2 | 0.00850825 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0084571 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00835438 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.00831296 |
| FLNB | filamin B, beta | 0.00826177 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00819963 |
| TLL2 | tolloid-like 2 | 0.00819401 |
| ANO6 | anoctamin 6 | 0.0081275 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.00807253 |
| EXOC6B | exocyst complex component 6B | 0.00804727 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00802888 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0080107 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.00797135 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00795477 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.239175 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.116127 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0960907 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0956733 |
| FN1 | fibronectin 1 | -0.0926468 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0819976 |
| HLA-B | major histocompatibility complex, class I, B | -0.0808465 |
| VIM | vimentin | -0.0672816 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0667059 |
| B2M | beta-2-microglobulin | -0.0614662 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0602475 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0595904 |
| FTL | ferritin, light polypeptide | -0.0593751 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0571727 |
| MT2A | metallothionein 2A | -0.0485123 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0463722 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0460109 |
| TPM4 | tropomyosin 4 | -0.0421478 |
| CANX | calnexin | -0.039737 |
| CD44 | CD44 molecule (Indian blood group) | -0.0389604 |
| H3-3B | H3.3 histone B | -0.0387161 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0386293 |
| MKI67 | marker of proliferation Ki-67 | -0.0378336 |
| LOX | lysyl oxidase | -0.0375891 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0356498 |
| CALU | calumenin | -0.0353264 |
| NLGN1 | neuroligin 1 | -0.0347507 |
| TXNRD1 | thioredoxin reductase 1 | -0.0339682 |
| TMSB10 | thymosin beta 10 | -0.0337083 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0322604 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0321099 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319948 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0298727 |
| PRSS23 | protease, serine, 23 | -0.0298365 |
| PGK1 | phosphoglycerate kinase 1 | -0.0298003 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0292288 |
| KYNU | kynureninase | -0.0291549 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0286092 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0282758 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0277049 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0264485 |
| ANKRD28 | ankyrin repeat domain 28 | -0.026346 |
| RPS6 | ribosomal protein S6 | -0.0261015 |
| OSMR | oncostatin M receptor | -0.0256353 |
| HLA-A | major histocompatibility complex, class I, A | -0.0254135 |
| PTK2 | protein tyrosine kinase 2 | -0.0246616 |
| SMC4 | structural maintenance of chromosomes 4 | -0.024618 |
| GNAS | GNAS complex locus | -0.0245766 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0245031 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0242243 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0241975 |
| RPS13 | ribosomal protein S13 | -0.0237521 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0236296 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0234392 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0226454 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0226121 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0225939 |
| IGF2 | insulin-like growth factor 2 | -0.0224693 |
| RNF216 | ring finger protein 216 | -0.0224134 |
| GDF15 | growth differentiation factor 15 | -0.022357 |
| SEPTIN7 | septin 7 | -0.0222649 |
| PXDN | peroxidasin | -0.0221754 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0221134 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0220713 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0220162 |
| RTN4 | reticulon 4 | -0.0219851 |
| CBX3 | chromobox homolog 3 | -0.0219108 |
| CENPF | centromere protein F, 350/400kDa | -0.0216755 |
| NAV3 | neuron navigator 3 | -0.0216388 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0214273 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0213347 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0212059 |
| SQSTM1 | sequestosome 1 | -0.0211766 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0211099 |
| TENM3 | teneurin transmembrane protein 3 | -0.0210527 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.021035 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0209479 |
| POTEF | POTE ankyrin domain family, member F | -0.0207739 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0207562 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0199907 |
| JMJD1C | jumonji domain containing 1C | -0.0198877 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0195667 |
| GLG1 | golgi glycoprotein 1 | -0.0195199 |
| ASPH | aspartate beta-hydroxylase | -0.0193964 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0192818 |
| TNS3 | tensin 3 | -0.0192442 |
| CD99 | CD99 molecule | -0.0191691 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.019112 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0190515 |
| RPS8 | ribosomal protein S8 | -0.018937 |
| NF1 | neurofibromin 1 | -0.0188764 |
| RPL28 | ribosomal protein L28 | -0.0188535 |
| NOP58 | NOP58 ribonucleoprotein | -0.0188436 |
| COL5A2 | collagen, type V, alpha 2 | -0.018672 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0185535 |
| LDHA | lactate dehydrogenase A | -0.0185381 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0184339 |
| ENO1 | enolase 1, (alpha) | -0.0183996 |
| GOLGA4 | golgin A4 | -0.0183369 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0180512 |
