| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CREB5 | cAMP responsive element binding protein 5 | 0.0584522 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0444771 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0399359 |
| APP | amyloid beta (A4) precursor protein | 0.0317662 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0310955 |
| TXNRD1 | thioredoxin reductase 1 | 0.0310487 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0299304 |
| RNF145 | ring finger protein 145 | 0.0295937 |
| NCKAP1 | NCK-associated protein 1 | 0.0288727 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0288157 |
| PARD3 | par-3 family cell polarity regulator | 0.0283772 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0283628 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258532 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0254242 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0252505 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0243442 |
| TFG | TRK-fused gene | 0.0243048 |
| ZNF292 | zinc finger protein 292 | 0.0240599 |
| RLF | rearranged L-myc fusion | 0.0238577 |
| USP3 | ubiquitin specific peptidase 3 | 0.0237886 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0226701 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0225588 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0217458 |
| MATR3 | matrin 3 | 0.0212785 |
| CCNL1 | cyclin L1 | 0.0202831 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0201736 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0201201 |
| RHOA | ras homolog family member A | 0.0200381 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.02 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0199871 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0180586 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0177755 |
| RHOB | ras homolog family member B | 0.0177385 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.01764 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0169898 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0168403 |
| YTHDC1 | YTH domain containing 1 | 0.0167639 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0163394 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0159013 |
| CLINT1 | clathrin interactor 1 | 0.0157348 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0156288 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0156206 |
| EREG | epiregulin | 0.0156173 |
| UBQLN1 | ubiquilin 1 | 0.0155277 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0155081 |
| CCNT2 | cyclin T2 | 0.0153749 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0152813 |
| SPOPL | speckle-type POZ protein-like | 0.0152607 |
| CDC73 | cell division cycle 73 | 0.0152124 |
| OGA | O-GlcNAcase | 0.0150955 |
| HDAC3 | histone deacetylase 3 | 0.0149889 |
| FNBP1L | formin binding protein 1-like | 0.0149222 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0148873 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0147877 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0140461 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0140413 |
| RREB1 | ras responsive element binding protein 1 | 0.0139031 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0138956 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.013876 |
| HELZ | helicase with zinc finger | 0.0138729 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0138162 |
| WDR45B | WD repeat domain 45B | 0.0138016 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0137573 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.0134914 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0133842 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0131098 |
| TTK | TTK protein kinase | 0.012705 |
| RBM27 | RNA binding motif protein 27 | 0.0126725 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0126461 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0125926 |
| TMEM39A | transmembrane protein 39A | 0.0125889 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0125239 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0125019 |
| MTMR3 | myotubularin related protein 3 | 0.0124587 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0123919 |
| UPP1 | uridine phosphorylase 1 | 0.0123867 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0122708 |
| PGK1 | phosphoglycerate kinase 1 | 0.0121854 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0120402 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.0120329 |
| CASC3 | cancer susceptibility candidate 3 | 0.0119063 |
| SERINC1 | serine incorporator 1 | 0.0118979 |
| RIOK3 | RIO kinase 3 | 0.0118818 |
| HBP1 | HMG-box transcription factor 1 | 0.0118736 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0118065 |
| LMBRD1 | LMBR1 domain containing 1 | 0.0117914 |
| DENND5A | DENN/MADD domain containing 5A | 0.0117302 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0114705 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0114564 |
| SNX9 | sorting nexin 9 | 0.0114543 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0114058 |
| AFDN | afadin, adherens junction formation factor | 0.0114051 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0113194 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0112694 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.011202 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0111619 |
| SNX4 | sorting nexin 4 | 0.0110692 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0110611 |
| PREPL | prolyl endopeptidase-like | 0.0110592 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0110271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.159546 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.129969 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.112762 |
| TMSB10 | thymosin beta 10 | -0.0997294 |
| ACTG1 | actin gamma 1 | -0.0883512 |
| PRELID2 | PRELI domain containing 2 | -0.0883459 |
| RAD51B | RAD51 paralog B | -0.0879759 |
| MT2A | metallothionein 2A | -0.085288 |
| LAMA4 | laminin, alpha 4 | -0.0833962 |
| HMGA2 | high mobility group AT-hook 2 | -0.0831786 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0802251 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0782775 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.076336 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0739667 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0708628 |
| VCL | vinculin | -0.0697363 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0696851 |
| EGFR | epidermal growth factor receptor | -0.0684197 |
| FHIT | fragile histidine triad | -0.0680306 |
| CCND1 | cyclin D1 | -0.0661335 |
| TPM4 | tropomyosin 4 | -0.0645373 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0619301 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0603061 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.058164 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0566654 |
| BPTF | bromodomain PHD finger transcription factor | -0.055007 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0540344 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0532599 |
| MACROD2 | MACRO domain containing 2 | -0.0531306 |
| FLNA | filamin A, alpha | -0.0518191 |
| CD44 | CD44 molecule (Indian blood group) | -0.0517163 |
| POTEF | POTE ankyrin domain family, member F | -0.0514427 |
| DIAPH3 | diaphanous-related formin 3 | -0.0512183 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0495687 |
| LAMC2 | laminin, gamma 2 | -0.04916 |
| FTL | ferritin, light polypeptide | -0.0488488 |
| PKM | pyruvate kinase, muscle | -0.0479918 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0478598 |
| FLNB | filamin B, beta | -0.0477034 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0473359 |
| HMGA1 | high mobility group AT-hook 1 | -0.0468417 |
| SMYD3 | SET and MYND domain containing 3 | -0.04663 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0451209 |
| SVIL | supervillin | -0.0441009 |
| RPS8 | ribosomal protein S8 | -0.043213 |
| WWOX | WW domain containing oxidoreductase | -0.0429135 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0425979 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0418722 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0418624 |
| RPL35A | ribosomal protein L35a | -0.0412022 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0411714 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0409751 |
| KRT7 | keratin 7, type II | -0.0408553 |
| SSH2 | slingshot protein phosphatase 2 | -0.0403456 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0402915 |
| RPS6 | ribosomal protein S6 | -0.0402827 |
| SEPTIN9 | septin 9 | -0.0398443 |
| RUNX1 | runt-related transcription factor 1 | -0.0389039 |
| PTMA | prothymosin, alpha | -0.0387259 |
| ATG7 | autophagy related 7 | -0.0378119 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0374033 |
| MKI67 | marker of proliferation Ki-67 | -0.0373648 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0371398 |
| ANXA3 | annexin A3 | -0.0371093 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.036471 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0363617 |
| ENO1 | enolase 1, (alpha) | -0.0362973 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0357891 |
| ACTN4 | actinin, alpha 4 | -0.0354099 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0351279 |
| EHBP1 | EH domain binding protein 1 | -0.0349008 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0348868 |
| PCNX4 | pecanex 4 | -0.0346683 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0346363 |
| PCED1B | PC-esterase domain containing 1B | -0.034508 |
| RPS19 | ribosomal protein S19 | -0.034374 |
| ERBIN | erbb2 interacting protein | -0.0341837 |
| WWC1 | WW and C2 domain containing 1 | -0.034181 |
| LAMB3 | laminin, beta 3 | -0.0340687 |
| FNIP1 | folliculin interacting protein 1 | -0.0339779 |
| CCDC138 | coiled-coil domain containing 138 | -0.033766 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0334847 |
| ZNF638 | zinc finger protein 638 | -0.0334504 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0334455 |
| LDHA | lactate dehydrogenase A | -0.0334284 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0333852 |
| RPL31 | ribosomal protein L31 | -0.0331567 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0331279 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0329199 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.032876 |
| INTS6 | integrator complex subunit 6 | -0.0323909 |
| EXOC4 | exocyst complex component 4 | -0.0322518 |
| NF1 | neurofibromin 1 | -0.0320702 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0320018 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0320017 |
| AEBP2 | AE binding protein 2 | -0.0319519 |
| DENND1A | DENN/MADD domain containing 1A | -0.0314578 |
| GPR39 | G protein-coupled receptor 39 | -0.0314156 |
| AHNAK | AHNAK nucleoprotein | -0.0313102 |
| ITGA6 | integrin, alpha 6 | -0.0302987 |
