| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0824561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0568376 |
| FAM13A | family with sequence similarity 13, member A | 0.0557507 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0492369 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0452983 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.035187 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0341758 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0302599 |
| PLEC | plectin | 0.0286522 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0251331 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0219115 |
| ANGPTL4 | angiopoietin-like 4 | 0.0204933 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0204878 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.020368 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0199564 |
| OGA | O-GlcNAcase | 0.0196865 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0195813 |
| NGLY1 | N-glycanase 1 | 0.0190585 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0182868 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0182329 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0182208 |
| RASA3 | RAS p21 protein activator 3 | 0.0179186 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0179081 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0177016 |
| HPCAL1 | hippocalcin-like 1 | 0.0172383 |
| DTNA | dystrobrevin, alpha | 0.0171746 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0168913 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0165597 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0163779 |
| TNS1 | tensin 1 | 0.0162859 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0162471 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0162347 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0159131 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0156757 |
| ARRDC3 | arrestin domain containing 3 | 0.0156366 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.015592 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0152554 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0150823 |
| CAPRIN2 | caprin family member 2 | 0.0147653 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0146924 |
| USP3 | ubiquitin specific peptidase 3 | 0.0145767 |
| CANX | calnexin | 0.0144039 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0138336 |
| GOLGA4 | golgin A4 | 0.0138 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0134503 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0132526 |
| DUSP6 | dual specificity phosphatase 6 | 0.0130482 |
| STC1 | stanniocalcin 1 | 0.0126902 |
| PDE10A | phosphodiesterase 10A | 0.0126694 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0125969 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0118153 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0104476 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0103113 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0102567 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0100987 |
| SUCO | SUN domain containing ossification factor | 0.00999878 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00998474 |
| MTSS1 | metastasis suppressor 1 | 0.00998105 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00991083 |
| ADM | adrenomedullin | 0.00984075 |
| EREG | epiregulin | 0.00978453 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00973644 |
| H1-4 | H1.4 linker histone, cluster member | 0.00950228 |
| ZNF654 | zinc finger protein 654 | 0.00944283 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00941133 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00937126 |
| NIBAN2 | niban apoptosis regulator 2 | 0.00936003 |
| HELZ | helicase with zinc finger | 0.00927339 |
| TAC4 | tachykinin 4 (hemokinin) | 0.00918589 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0091773 |
| NUP58 | nucleoporin 58 | 0.00913926 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.00912993 |
| IER3 | immediate early response 3 | 0.00892476 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.00876121 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00873756 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00865452 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.00862287 |
| RPL3 | ribosomal protein L3 | 0.00861289 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00852242 |
| DEPP1 | DEPP autophagy regulator 1 | 0.00848464 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00844 |
| SERINC1 | serine incorporator 1 | 0.0083683 |
| RPL13A | ribosomal protein L13a | 0.00822545 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00815376 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0080838 |
| SEPTIN9 | septin 9 | 0.00804996 |
| RPSA | ribosomal protein SA | 0.00804328 |
| RPS12 | ribosomal protein S12 | 0.00801276 |
| RLF | rearranged L-myc fusion | 0.00798417 |
| ATP13A3 | ATPase type 13A3 | 0.00793523 |
| KLF6 | Kruppel-like factor 6 | 0.00793245 |
| RPL4 | ribosomal protein L4 | 0.00786315 |
| WDR45B | WD repeat domain 45B | 0.007848 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00780182 |
| EPN2 | epsin 2 | 0.00779221 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00776923 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.00769988 |
| SQSTM1 | sequestosome 1 | 0.00765889 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00761743 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00748447 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.427811 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.318724 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.19519 |
| IGF2 | insulin-like growth factor 2 | -0.151408 |
| TMSB10 | thymosin beta 10 | -0.138551 |
| FN1 | fibronectin 1 | -0.106946 |
| CD44 | CD44 molecule (Indian blood group) | -0.099896 |
| ACTG1 | actin gamma 1 | -0.0956443 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0912816 |
| NAV1 | neuron navigator 1 | -0.0892358 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0844073 |
| MYO10 | myosin X | -0.0786708 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0758524 |
| POTEF | POTE ankyrin domain family, member F | -0.0684544 |
| DST | dystonin | -0.0620118 |
| RAI14 | retinoic acid induced 14 | -0.0582616 |
| COL5A1 | collagen, type V, alpha 1 | -0.0580317 |
| CLMP | CXADR-like membrane protein | -0.0570209 |
| HMGA2 | high mobility group AT-hook 2 | -0.0556203 |
| VCL | vinculin | -0.054181 |
| EGR1 | early growth response 1 | -0.053672 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0530102 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.049674 |
| ASPH | aspartate beta-hydroxylase | -0.0490133 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0482095 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0475432 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0468961 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0461912 |
| ENO1 | enolase 1, (alpha) | -0.0451148 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0438303 |
| TENM2 | teneurin transmembrane protein 2 | -0.0434391 |
| RPS6 | ribosomal protein S6 | -0.0424949 |
| CDH13 | cadherin 13 | -0.0411203 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0400947 |
| TUBB6 | tubulin, beta 6 class V | -0.0397927 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0396614 |
| DIAPH2 | diaphanous-related formin 2 | -0.0390654 |
| MAP1B | microtubule-associated protein 1B | -0.0385591 |
| MT2A | metallothionein 2A | -0.0382111 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0377368 |
| TPM4 | tropomyosin 4 | -0.037623 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0373789 |
| ANXA2 | annexin A2 | -0.0366012 |
| S100A10 | S100 calcium binding protein A10 | -0.0365086 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0364003 |
| COL1A1 | collagen, type I, alpha 1 | -0.0360812 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0355099 |
| CCND1 | cyclin D1 | -0.0354709 |
| NDRG1 | N-myc downstream regulated 1 | -0.0347743 |
| GLIS3 | GLIS family zinc finger 3 | -0.0345144 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0330891 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.032639 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0320525 |
| CENPF | centromere protein F, 350/400kDa | -0.0320245 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0313083 |
| TPM1 | tropomyosin 1 (alpha) | -0.0306295 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0303288 |
| MAP4 | microtubule-associated protein 4 | -0.0298539 |
| TPI1 | triosephosphate isomerase 1 | -0.0295316 |
| RPL35A | ribosomal protein L35a | -0.0295305 |
| ACTN4 | actinin, alpha 4 | -0.029507 |
| AXL | AXL receptor tyrosine kinase | -0.0292952 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0289613 |
| RAD51B | RAD51 paralog B | -0.0282354 |
| ATXN1 | ataxin 1 | -0.0279723 |
| PRSS23 | protease, serine, 23 | -0.0279717 |
| CLIC4 | chloride intracellular channel 4 | -0.02795 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0278861 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0278059 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0277082 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.027389 |
| PTMA | prothymosin, alpha | -0.0271521 |
| PTK2 | protein tyrosine kinase 2 | -0.0269214 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0267349 |
| CUX1 | cut-like homeobox 1 | -0.026411 |
| HMGA1 | high mobility group AT-hook 1 | -0.0263201 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0262652 |
| PFN1 | profilin 1 | -0.0261609 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0261182 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0260886 |
| BPTF | bromodomain PHD finger transcription factor | -0.026025 |
| RRM2 | ribonucleotide reductase M2 | -0.0259875 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.025947 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0257596 |
| CCDC91 | coiled-coil domain containing 91 | -0.0256698 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255474 |
| FRMD4A | FERM domain containing 4A | -0.0252542 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0251947 |
| RTN4 | reticulon 4 | -0.0248384 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0243546 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0242982 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.024231 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0241975 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0241862 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0241733 |
| DIAPH3 | diaphanous-related formin 3 | -0.0240004 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0239631 |
| PGK1 | phosphoglycerate kinase 1 | -0.0238067 |
| LDHA | lactate dehydrogenase A | -0.0237663 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0237299 |
