| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.105311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103615 |
| RAD21 | RAD21 homolog (S. pombe) | 0.091074 |
| TXNRD1 | thioredoxin reductase 1 | 0.0792463 |
| SMAD3 | SMAD family member 3 | 0.0740081 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0719917 |
| KRT18 | keratin 18, type I | 0.0702615 |
| RPL23 | ribosomal protein L23 | 0.0685671 |
| LMO7 | LIM domain 7 | 0.0649965 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0634931 |
| RPS19 | ribosomal protein S19 | 0.047477 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0463568 |
| RPL18 | ribosomal protein L18 | 0.0451925 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0442252 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0426576 |
| FAT1 | FAT atypical cadherin 1 | 0.0400217 |
| RPL4 | ribosomal protein L4 | 0.0388942 |
| SET | SET nuclear proto-oncogene | 0.0387256 |
| RPS12 | ribosomal protein S12 | 0.0385453 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0374226 |
| ABHD2 | abhydrolase domain containing 2 | 0.0368637 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.036232 |
| RPL21 | ribosomal protein L21 | 0.0359112 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0356125 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0351134 |
| TPI1 | triosephosphate isomerase 1 | 0.0346565 |
| MYO5B | myosin VB | 0.034619 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0345164 |
| TPM3 | tropomyosin 3 | 0.0342237 |
| HYOU1 | hypoxia up-regulated 1 | 0.0333887 |
| RPL3 | ribosomal protein L3 | 0.0333149 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0321778 |
| DSPP | dentin sialophosphoprotein | 0.031224 |
| HMGB2 | high mobility group box 2 | 0.0311538 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0307799 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0304947 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0296585 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0295119 |
| KLF6 | Kruppel-like factor 6 | 0.0294297 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0293407 |
| AHNAK | AHNAK nucleoprotein | 0.0289788 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0280628 |
| PDZD8 | PDZ domain containing 8 | 0.0279661 |
| RPS2 | ribosomal protein S2 | 0.0276084 |
| NTN4 | netrin 4 | 0.0271947 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0270903 |
| RPS3 | ribosomal protein S3 | 0.0261654 |
| SQSTM1 | sequestosome 1 | 0.0259125 |
| RPLP1 | ribosomal protein, large, P1 | 0.0251466 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0247 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0244113 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.024361 |
| KIF5B | kinesin family member 5B | 0.0235587 |
| RPL12 | ribosomal protein L12 | 0.0232453 |
| PLK2 | polo-like kinase 2 | 0.0231706 |
| RPL26 | ribosomal protein L26 | 0.0230843 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0229336 |
| ASPH | aspartate beta-hydroxylase | 0.0227687 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0226966 |
| ENO1 | enolase 1, (alpha) | 0.0223227 |
| KRT20 | keratin 20, type I | 0.0223132 |
| LAMA4 | laminin, alpha 4 | 0.0222884 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0219085 |
| XPO1 | exportin 1 | 0.0216974 |
| SKP1 | S-phase kinase-associated protein 1 | 0.021482 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0213839 |
| MKI67 | marker of proliferation Ki-67 | 0.0211229 |
| ANXA1 | annexin A1 | 0.0207494 |
| RPL13A | ribosomal protein L13a | 0.0207068 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0206559 |
| CENPF | centromere protein F, 350/400kDa | 0.020402 |
| RPS15A | ribosomal protein S15a | 0.0203029 |
| IFNGR1 | interferon gamma receptor 1 | 0.020252 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0200456 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0200149 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0199651 |
| KRT8 | keratin 8, type II | 0.0197427 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0195774 |
| IPO7 | importin 7 | 0.0193881 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.01919 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0190538 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0188806 |
| ETV6 | ets variant 6 | 0.0188323 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0188225 |
| FOXO1 | forkhead box O1 | 0.0187471 |
| RPS17 | ribosomal protein S17 | 0.0186853 |
| SGMS2 | sphingomyelin synthase 2 | 0.0185196 |
| MMP7 | matrix metallopeptidase 7 | 0.0185127 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0184891 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0184129 |
| RPL7 | ribosomal protein L7 | 0.0183891 |
| RASEF | RAS and EF-hand domain containing | 0.0183831 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0181052 |
| LAMB3 | laminin, beta 3 | 0.0180076 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0179497 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.017947 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0176203 |
| RPS9 | ribosomal protein S9 | 0.0172396 |
| SLK | STE20-like kinase | 0.0172325 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0171252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.243185 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148812 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.129481 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0797907 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0746894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0711886 |
| INTS6 | integrator complex subunit 6 | -0.0708445 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0704502 |
| EGR1 | early growth response 1 | -0.070236 |
| WASF2 | WAS protein family, member 2 | -0.0646475 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0638329 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0618823 |
| POTEF | POTE ankyrin domain family, member F | -0.058397 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0555747 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.05551 |
| NF1 | neurofibromin 1 | -0.0540384 |
| FRY | furry homolog (Drosophila) | -0.051008 |
| RPS13 | ribosomal protein S13 | -0.0510053 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0506309 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0503357 |
| ACTG1 | actin gamma 1 | -0.0499436 |
| RPL35A | ribosomal protein L35a | -0.0499003 |
| ACTN4 | actinin, alpha 4 | -0.0489651 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0464174 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0451424 |
| HM13 | histocompatibility (minor) 13 | -0.044769 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0444211 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.043925 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0432445 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0432237 |
| BPTF | bromodomain PHD finger transcription factor | -0.0427173 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0406619 |
| RPS23 | ribosomal protein S23 | -0.0406301 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0393026 |
| WDR45B | WD repeat domain 45B | -0.0387147 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0381996 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0364285 |
| GOLGA4 | golgin A4 | -0.0362277 |
| FTL | ferritin, light polypeptide | -0.0355522 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0347061 |
| THOC2 | THO complex 2 | -0.0339117 |
| ANXA2 | annexin A2 | -0.03368 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0332713 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0326595 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0325396 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0323238 |
| ARF4 | ADP-ribosylation factor 4 | -0.0320945 |
| AGR2 | anterior gradient 2 | -0.0316937 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0314706 |
| UBC | ubiquitin C | -0.0313177 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.031062 |
| DGKH | diacylglycerol kinase, eta | -0.0310142 |
| BBX | bobby sox homolog (Drosophila) | -0.0306999 |
| EXOC4 | exocyst complex component 4 | -0.0304616 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0302823 |
| SBF2 | SET binding factor 2 | -0.0301764 |
| AREG | amphiregulin | -0.0301692 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0301384 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0300556 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0298847 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0296044 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0288598 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0284414 |
| FBXO11 | F-box protein 11 | -0.0284128 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0282262 |
| RPS21 | ribosomal protein S21 | -0.0282262 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.02817 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0280856 |
| HLA-A | major histocompatibility complex, class I, A | -0.0279424 |
| ZNF207 | zinc finger protein 207 | -0.0278934 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0277663 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0277632 |
| VIM | vimentin | -0.0274855 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0269984 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0267206 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0266614 |
| GNAS | GNAS complex locus | -0.0265855 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0265157 |
| LDHA | lactate dehydrogenase A | -0.0262758 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0261669 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0261441 |
| ATM | ATM serine/threonine kinase | -0.026123 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0260497 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0260265 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0259872 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0258786 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0258785 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0258634 |
| RPL31 | ribosomal protein L31 | -0.025795 |
| DIAPH2 | diaphanous-related formin 2 | -0.0257838 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0253727 |
| PCBP2 | poly(rC) binding protein 2 | -0.0253273 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0252639 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0252546 |
| NBEAL1 | neurobeachin-like 1 | -0.0250952 |
| CTBP2 | C-terminal binding protein 2 | -0.0249855 |
| DNM2 | dynamin 2 | -0.0249756 |
| GLG1 | golgi glycoprotein 1 | -0.0249232 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0249206 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0249074 |
