| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.168307 |
| ATXN1 | ataxin 1 | 0.104462 |
| DST | dystonin | 0.1044 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0996642 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0835534 |
| APOB | apolipoprotein B | 0.0829833 |
| PEG3 | paternally expressed 3 | 0.0720832 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0679075 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0636814 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0584132 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0580677 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0571922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0571781 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0554321 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.054789 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0537466 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0531294 |
| DTNA | dystrobrevin, alpha | 0.0497363 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0486025 |
| TF | transferrin | 0.0478849 |
| ITGAV | integrin, alpha V | 0.0444494 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0408335 |
| FN1 | fibronectin 1 | 0.0390137 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0390129 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0381865 |
| ENAH | enabled homolog (Drosophila) | 0.0357371 |
| ENO1 | enolase 1, (alpha) | 0.0350459 |
| KLF6 | Kruppel-like factor 6 | 0.0349855 |
| KYNU | kynureninase | 0.0338215 |
| AHNAK | AHNAK nucleoprotein | 0.0338166 |
| JMJD1C | jumonji domain containing 1C | 0.033554 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0324474 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0320198 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0307832 |
| AFDN | afadin, adherens junction formation factor | 0.0301657 |
| SDC4 | syndecan 4 | 0.02903 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0285728 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0266181 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0262704 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0261536 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0258797 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0253917 |
| MYO5B | myosin VB | 0.0249617 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0247036 |
| FLNB | filamin B, beta | 0.0232291 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.022538 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0224632 |
| DUSP16 | dual specificity phosphatase 16 | 0.0223819 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0223577 |
| GK | glycerol kinase | 0.0221374 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0219015 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.021628 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0215138 |
| GRB10 | growth factor receptor-bound protein 10 | 0.021245 |
| RHOB | ras homolog family member B | 0.0212349 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0208899 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0206964 |
| MSI2 | musashi RNA-binding protein 2 | 0.0204971 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0203041 |
| ZNF644 | zinc finger protein 644 | 0.0202202 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0202151 |
| RNF213 | ring finger protein 213 | 0.0201251 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0200661 |
| PLIN2 | perilipin 2 | 0.0199101 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.019807 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0197771 |
| MAP1B | microtubule-associated protein 1B | 0.0195835 |
| FMNL2 | formin-like 2 | 0.019036 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0189909 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0189824 |
| PHF3 | PHD finger protein 3 | 0.018813 |
| JAK1 | Janus kinase 1 | 0.0187957 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0186577 |
| MRTFA | myocardin related transcription factor A | 0.0186564 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0185482 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0184771 |
| TNS1 | tensin 1 | 0.0184051 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.01837 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.018326 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0183134 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0182533 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.018169 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0180143 |
| JUN | jun proto-oncogene | 0.017759 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.017707 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0176422 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0174746 |
| CD109 | CD109 molecule | 0.0173513 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0172813 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0172544 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0171718 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0171268 |
| FAM107B | family with sequence similarity 107, member B | 0.0171086 |
| TMEM181 | transmembrane protein 181 | 0.0171085 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0170702 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0170481 |
| RORA | RAR-related orphan receptor A | 0.0170465 |
| YME1L1 | YME1-like 1 ATPase | 0.0169625 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0169323 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0167903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.397496 |
| IGF2 | insulin-like growth factor 2 | -0.320037 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.126362 |
| MT2A | metallothionein 2A | -0.0811697 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0745857 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0468733 |
| RPS6 | ribosomal protein S6 | -0.0428544 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0418666 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0382062 |
| RPL37A | ribosomal protein L37a | -0.0371032 |
| RPS12 | ribosomal protein S12 | -0.0353544 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329763 |
| FTL | ferritin, light polypeptide | -0.0328267 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0314433 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0295171 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0291745 |
| HMGA1 | high mobility group AT-hook 1 | -0.0289377 |
| RPL37 | ribosomal protein L37 | -0.027469 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0274646 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0271113 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0269951 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0268682 |
| ITGA1 | integrin, alpha 1 | -0.0258933 |
| RPS19 | ribosomal protein S19 | -0.0254036 |
| PKP4 | plakophilin 4 | -0.0246155 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0241166 |
| CRLS1 | cardiolipin synthase 1 | -0.0234568 |
| RPL35A | ribosomal protein L35a | -0.0231673 |
| RPL34 | ribosomal protein L34 | -0.0231292 |
| RPL26 | ribosomal protein L26 | -0.0220273 |
| APOA2 | apolipoprotein A-II | -0.0218999 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0214753 |
| RPL11 | ribosomal protein L11 | -0.0212696 |
| RPLP0 | ribosomal protein, large, P0 | -0.0210435 |
| RPS8 | ribosomal protein S8 | -0.0208204 |
| RPS14 | ribosomal protein S14 | -0.0208072 |
| RPLP2 | ribosomal protein, large, P2 | -0.0205023 |
| AHSG | alpha-2-HS-glycoprotein | -0.0202708 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.019609 |
| SETD5 | SET domain containing 5 | -0.0194609 |
| EGR1 | early growth response 1 | -0.0188239 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0187968 |
| RPL23 | ribosomal protein L23 | -0.0185916 |
| RPS21 | ribosomal protein S21 | -0.0183061 |
| POTEF | POTE ankyrin domain family, member F | -0.0182644 |
| CPE | carboxypeptidase E | -0.0179543 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0179485 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0177846 |
| RPL30 | ribosomal protein L30 | -0.0174502 |
| RPL5 | ribosomal protein L5 | -0.0173091 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0172515 |
| RBM25 | RNA binding motif protein 25 | -0.0172107 |
| CNKSR3 | CNKSR family member 3 | -0.017015 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0166771 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0166694 |
| ACTG1 | actin gamma 1 | -0.0165788 |
| C3 | complement component 3 | -0.016566 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0165406 |
| FAT1 | FAT atypical cadherin 1 | -0.0161943 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0161501 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0160264 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0159463 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0156292 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0154929 |
| RPL9 | ribosomal protein L9 | -0.0154169 |
| RPL12 | ribosomal protein L12 | -0.015292 |
| RPL28 | ribosomal protein L28 | -0.0152913 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0151213 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | -0.0151111 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0150198 |
| RPL31 | ribosomal protein L31 | -0.0150065 |
| CCN2 | cellular communication network factor 2 | -0.01499 |
| RPS3 | ribosomal protein S3 | -0.0148817 |
| RFX7 | regulatory factor X, 7 | -0.0147466 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0145651 |
| RACK1 | receptor for activated C kinase 1 | -0.0144563 |
| PFN1 | profilin 1 | -0.0144032 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0143882 |
| WDR45B | WD repeat domain 45B | -0.014232 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0141192 |
| RPS24 | ribosomal protein S24 | -0.0140152 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0138359 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0138275 |
| RPS10 | ribosomal protein S10 | -0.0138145 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0137791 |
| CDC7 | cell division cycle 7 | -0.013391 |
| CST3 | cystatin C | -0.0133151 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.013233 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0131975 |
| ARHGAP9 | Rho GTPase activating protein 9 | -0.0130603 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0130426 |
| RPL27A | ribosomal protein L27a | -0.0129359 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0125974 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.012201 |
| APOE | apolipoprotein E | -0.0121709 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0121659 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0120841 |
| FRMD5 | FERM domain containing 5 | -0.0120809 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0120132 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0119528 |
