| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.114636 |
| PTMA | prothymosin, alpha | 0.104844 |
| MEF2A | myocyte enhancer factor 2A | 0.100608 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0965855 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0864238 |
| LMO7 | LIM domain 7 | 0.0807169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0729568 |
| SQLE | squalene epoxidase | 0.0722054 |
| ENO1 | enolase 1, (alpha) | 0.0687486 |
| KRT17 | keratin 17, type I | 0.0684329 |
| ANXA1 | annexin A1 | 0.0618065 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602958 |
| PGK1 | phosphoglycerate kinase 1 | 0.0575851 |
| OGA | O-GlcNAcase | 0.0562037 |
| SPAG9 | sperm associated antigen 9 | 0.0559038 |
| RAI14 | retinoic acid induced 14 | 0.0530025 |
| LMNA | lamin A/C | 0.0525932 |
| MTSS1 | metastasis suppressor 1 | 0.05168 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0511573 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0509007 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0494886 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0477475 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0474606 |
| DSPP | dentin sialophosphoprotein | 0.0456176 |
| PLEC | plectin | 0.0445339 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0444011 |
| AHNAK | AHNAK nucleoprotein | 0.0435256 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0428923 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0427679 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0420877 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.041308 |
| SH3PXD2A | SH3 and PX domains 2A | 0.041148 |
| CANX | calnexin | 0.0400169 |
| TMSB4X | thymosin beta 4, X-linked | 0.0399706 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0395781 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0393858 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.03889 |
| EZR | ezrin | 0.0384737 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0381976 |
| KRT6A | keratin 6A, type II | 0.0378241 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0377541 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0373532 |
| KIF16B | kinesin family member 16B | 0.0366095 |
| GLYAT | glycine-N-acyltransferase | 0.0359368 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0358626 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0353542 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0352826 |
| MSN | moesin | 0.0352048 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0350979 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.034893 |
| RPL3 | ribosomal protein L3 | 0.0344386 |
| KRT14 | keratin 14, type I | 0.0342683 |
| COPA | coatomer protein complex, subunit alpha | 0.0341983 |
| AOPEP | aminopeptidase O (putative) | 0.0338222 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.033809 |
| SUCO | SUN domain containing ossification factor | 0.0335753 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0333485 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0332999 |
| H1-0 | H1.0 linker histone | 0.0330468 |
| SQSTM1 | sequestosome 1 | 0.0328922 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0326695 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.032355 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0323107 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0322177 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0319832 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0319394 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0311 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0310776 |
| NECTIN4 | nectin cell adhesion molecule 4 | 0.0302204 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0295888 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0290999 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0290846 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0289388 |
| FAM13A | family with sequence similarity 13, member A | 0.0287404 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0287037 |
| KIAA1217 | KIAA1217 | 0.0283525 |
| DOK5 | docking protein 5 | 0.0279932 |
| RNF145 | ring finger protein 145 | 0.0276114 |
| DENND4C | DENN/MADD domain containing 4C | 0.0275078 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0274977 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0274374 |
| HELZ | helicase with zinc finger | 0.0273686 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0270899 |
| TFG | TRK-fused gene | 0.0268894 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0266771 |
| FOXO3 | forkhead box O3 | 0.0266314 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.026497 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0262924 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0262663 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0262422 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0258705 |
| GOLGA4 | golgin A4 | 0.025818 |
| KLF6 | Kruppel-like factor 6 | 0.0255448 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0251103 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0250236 |
| HDLBP | high density lipoprotein binding protein | 0.0247766 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0247128 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245548 |
| FNIP1 | folliculin interacting protein 1 | 0.0245189 |
| XPO1 | exportin 1 | 0.0244779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.128274 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.118954 |
| FLNB | filamin B, beta | -0.109317 |
| DOCK5 | dedicator of cytokinesis 5 | -0.104968 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0948531 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0935835 |
| BCL2L1 | BCL2-like 1 | -0.0917609 |
| POTEF | POTE ankyrin domain family, member F | -0.0902775 |
| MT2A | metallothionein 2A | -0.0899299 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0876528 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.083606 |
| RIN2 | Ras and Rab interactor 2 | -0.0739835 |
| CD44 | CD44 molecule (Indian blood group) | -0.0712907 |
| OSMR | oncostatin M receptor | -0.0708875 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0702999 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.068193 |
| DPYD | dihydropyrimidine dehydrogenase | -0.061852 |
| RASAL2 | RAS protein activator like 2 | -0.0543755 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0526652 |
| RPS21 | ribosomal protein S21 | -0.0499837 |
| CDK6 | cyclin-dependent kinase 6 | -0.0448134 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0447659 |
| FOSL1 | FOS-like antigen 1 | -0.0440115 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0438803 |
| CMIP | c-Maf inducing protein | -0.0432812 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0432448 |
| HMGA2 | high mobility group AT-hook 2 | -0.0427404 |
| NRG1 | neuregulin 1 | -0.04251 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0420544 |
| VCL | vinculin | -0.0415118 |
| LUZP1 | leucine zipper protein 1 | -0.0411913 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0392509 |
| LAMA5 | laminin, alpha 5 | -0.039158 |
| KIAA0040 | KIAA0040 | -0.0387221 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0387106 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0381201 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.038033 |
| SMYD3 | SET and MYND domain containing 3 | -0.037482 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0371571 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0370703 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0370062 |
| FRMD5 | FERM domain containing 5 | -0.0369309 |
| CDCP1 | CUB domain containing protein 1 | -0.0357006 |
| FOXO1 | forkhead box O1 | -0.0352937 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.034908 |
| HLA-B | major histocompatibility complex, class I, B | -0.0348578 |
| DUSP4 | dual specificity phosphatase 4 | -0.0347238 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0342214 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.033967 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0335969 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0327782 |
| ACTN4 | actinin, alpha 4 | -0.0327085 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0326563 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0323477 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0323303 |
| EFHD2 | EF-hand domain family, member D2 | -0.0318753 |
| PLAT | plasminogen activator, tissue | -0.0317968 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0316789 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0314424 |
| HM13 | histocompatibility (minor) 13 | -0.030816 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.030754 |
| EGR1 | early growth response 1 | -0.0298894 |
| RPS19 | ribosomal protein S19 | -0.0298439 |
| SOX7 | SRY (sex determining region Y)-box 7 | -0.0295754 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0294584 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0294583 |
| IGF2 | insulin-like growth factor 2 | -0.0292995 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0292336 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.029226 |
| TNS4 | tensin 4 | -0.0289256 |
| JAG1 | jagged 1 | -0.0287555 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0287027 |
| LAMC2 | laminin, gamma 2 | -0.0284616 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0284302 |
| PODXL | podocalyxin-like | -0.028137 |
| TXNRD1 | thioredoxin reductase 1 | -0.0281066 |
| RIGI | RNA sensor RIG-I | -0.0277598 |
| SMAD3 | SMAD family member 3 | -0.0277509 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0277079 |
| EFNA5 | ephrin-A5 | -0.0276624 |
| S100A10 | S100 calcium binding protein A10 | -0.0276029 |
| EPHA2 | EPH receptor A2 | -0.0275074 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0272474 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0271455 |
| RPS13 | ribosomal protein S13 | -0.0269172 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0265998 |
| ANTXR2 | anthrax toxin receptor 2 | -0.026475 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0262538 |
| SLTM | SAFB-like, transcription modulator | -0.0262246 |
| ACTG1 | actin gamma 1 | -0.0260915 |
| NEK7 | NIMA-related kinase 7 | -0.0259997 |
| RPS23 | ribosomal protein S23 | -0.0259557 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0258998 |
| CAPRIN2 | caprin family member 2 | -0.0256164 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0255812 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0255082 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0252848 |
| LDLR | low density lipoprotein receptor | -0.0252276 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0252081 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0251591 |
