| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.126172 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0734382 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0600489 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0592906 |
| MSI2 | musashi RNA-binding protein 2 | 0.0480878 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0454408 |
| KRT17 | keratin 17, type I | 0.0426108 |
| FNDC3B | fibronectin type III domain containing 3B | 0.041191 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0389747 |
| PTMA | prothymosin, alpha | 0.0385378 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0384265 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0370197 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0366979 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0365828 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0347694 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0342551 |
| MYO5B | myosin VB | 0.0326638 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.030539 |
| RNF145 | ring finger protein 145 | 0.0286809 |
| COG5 | component of oligomeric golgi complex 5 | 0.0273252 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0272704 |
| SNX13 | sorting nexin 13 | 0.0264105 |
| YTHDC1 | YTH domain containing 1 | 0.0259132 |
| TES | testin LIM domain protein | 0.0258149 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0256886 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0255203 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0254898 |
| KLF6 | Kruppel-like factor 6 | 0.0253191 |
| RHOA | ras homolog family member A | 0.0250828 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0249749 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0246021 |
| SPAG9 | sperm associated antigen 9 | 0.023989 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0235297 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0234601 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0234436 |
| DSPP | dentin sialophosphoprotein | 0.0232252 |
| KLHL24 | kelch-like family member 24 | 0.0223311 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0222174 |
| AFTPH | aftiphilin | 0.0217922 |
| ATF3 | activating transcription factor 3 | 0.0217187 |
| KIAA1671 | KIAA1671 | 0.0214912 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0213972 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0212133 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0211692 |
| USP3 | ubiquitin specific peptidase 3 | 0.0211538 |
| LAMB3 | laminin, beta 3 | 0.0210533 |
| KRT19 | keratin 19, type I | 0.0209521 |
| OGA | O-GlcNAcase | 0.0207198 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0206614 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0206491 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0205099 |
| RHOB | ras homolog family member B | 0.0204156 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0203126 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0202905 |
| HELZ | helicase with zinc finger | 0.0202635 |
| LPIN2 | lipin 2 | 0.0201552 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0200569 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0199814 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0199679 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.019836 |
| CCNY | cyclin Y | 0.0198351 |
| ATP11B | ATPase, class VI, type 11B | 0.0198251 |
| FNBP4 | formin binding protein 4 | 0.0198012 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0197234 |
| PTK2 | protein tyrosine kinase 2 | 0.0196821 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.01966 |
| TMEM45B | transmembrane protein 45B | 0.0196487 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0195346 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0193898 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0193676 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0193153 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0192946 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.019119 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0191106 |
| AREG | amphiregulin | 0.0190075 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0189298 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0186838 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0185407 |
| RPL13A | ribosomal protein L13a | 0.0184886 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0184762 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0183992 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0183069 |
| UBAC2 | UBA domain containing 2 | 0.0180825 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.017981 |
| ANXA1 | annexin A1 | 0.0179517 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0179474 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.0179026 |
| RAB18 | RAB18, member RAS oncogene family | 0.017899 |
| SRP54 | signal recognition particle 54kDa | 0.0178414 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0177995 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0176482 |
| ITGB8 | integrin, beta 8 | 0.0175094 |
| KLHL29 | kelch-like family member 29 | 0.0173307 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0173178 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0173002 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0172369 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0171538 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0171496 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0168349 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.016795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.198253 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.19589 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.161815 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122886 |
| EHBP1 | EH domain binding protein 1 | -0.121422 |
| ASPH | aspartate beta-hydroxylase | -0.116566 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112368 |
| FAT1 | FAT atypical cadherin 1 | -0.0994219 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0910797 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0894854 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0823959 |
| FLNB | filamin B, beta | -0.0722754 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0710462 |
| ITGA6 | integrin, alpha 6 | -0.064305 |
| ANXA2 | annexin A2 | -0.0622642 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0593832 |
| EMP1 | epithelial membrane protein 1 | -0.0582968 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0557897 |
| BCL2L1 | BCL2-like 1 | -0.0539477 |
| LMO7 | LIM domain 7 | -0.0534957 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0515953 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0514786 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0507228 |
| PGK1 | phosphoglycerate kinase 1 | -0.0506573 |
| WWC1 | WW and C2 domain containing 1 | -0.0494128 |
| POTEF | POTE ankyrin domain family, member F | -0.0494055 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0487326 |
| TMEM123 | transmembrane protein 123 | -0.0485125 |
| NPSR1 | neuropeptide S receptor 1 | -0.0477208 |
| AGR2 | anterior gradient 2 | -0.0463198 |
| S100A10 | S100 calcium binding protein A10 | -0.0459921 |
| RAD51B | RAD51 paralog B | -0.0446259 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0436632 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0432574 |
| ATM | ATM serine/threonine kinase | -0.0427821 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0426098 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0425444 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0425406 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0421764 |
| ACTN4 | actinin, alpha 4 | -0.0414135 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0412265 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0409686 |
| DSTN | destrin (actin depolymerizing factor) | -0.0399803 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0390987 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0384655 |
| EXOC4 | exocyst complex component 4 | -0.0376852 |
| EFNA5 | ephrin-A5 | -0.0376409 |
| YAP1 | Yes-associated protein 1 | -0.0373527 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0367337 |
| CDK6 | cyclin-dependent kinase 6 | -0.0357334 |
| BPTF | bromodomain PHD finger transcription factor | -0.0356686 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0355048 |
| PCDH7 | protocadherin 7 | -0.035114 |
| SEPTIN9 | septin 9 | -0.0350986 |
| RNF213 | ring finger protein 213 | -0.0350894 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0349667 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0349104 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0344199 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0344193 |
| RRBP1 | ribosome binding protein 1 | -0.0342761 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0341383 |
| POF1B | premature ovarian failure, 1B | -0.0339339 |
| WWOX | WW domain containing oxidoreductase | -0.0335349 |
| INTS6 | integrator complex subunit 6 | -0.0332636 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0330452 |
| DIAPH2 | diaphanous-related formin 2 | -0.0330044 |
| ACTG1 | actin gamma 1 | -0.0325196 |
| AHNAK | AHNAK nucleoprotein | -0.0318867 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0318784 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0317312 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0314076 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0310972 |
| LPIN1 | lipin 1 | -0.0308533 |
| PATJ | PATJ crumbs cell polarity complex component | -0.030512 |
| CANX | calnexin | -0.0305 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0304713 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.030277 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0299266 |
| NFIA | nuclear factor I/A | -0.0299009 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0296769 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0291383 |
| KRT8 | keratin 8, type II | -0.0291033 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0289515 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0288159 |
| ECT2 | epithelial cell transforming 2 | -0.0287456 |
| MEIS2 | Meis homeobox 2 | -0.0283779 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0282917 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0279973 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0279725 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0275485 |
| RPS8 | ribosomal protein S8 | -0.0273282 |
| HDLBP | high density lipoprotein binding protein | -0.0273203 |
| CCND1 | cyclin D1 | -0.0271794 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0271349 |
| MECOM | MDS1 and EVI1 complex locus | -0.0269263 |
| EPCAM | epithelial cell adhesion molecule | -0.0266271 |
| MTDH | metadherin | -0.0265815 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0265625 |
| LIMA1 | LIM domain and actin binding 1 | -0.0262342 |
| MKI67 | marker of proliferation Ki-67 | -0.0261564 |
