| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0822835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0475799 |
| AHNAK | AHNAK nucleoprotein | 0.047371 |
| FTL | ferritin, light polypeptide | 0.0453819 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0434668 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0428581 |
| PLEC | plectin | 0.042094 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.041327 |
| KLF6 | Kruppel-like factor 6 | 0.0406231 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0387292 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0366314 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0348865 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0341362 |
| SPAG9 | sperm associated antigen 9 | 0.0325245 |
| SERINC1 | serine incorporator 1 | 0.0289606 |
| H1-0 | H1.0 linker histone | 0.0288093 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0287764 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0283236 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0277482 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0276124 |
| TPI1 | triosephosphate isomerase 1 | 0.0265405 |
| ATP13A3 | ATPase type 13A3 | 0.0261881 |
| RTN4 | reticulon 4 | 0.0249777 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0240621 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0231729 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0231078 |
| OGA | O-GlcNAcase | 0.0230949 |
| CDK17 | cyclin-dependent kinase 17 | 0.0229646 |
| NCKAP1 | NCK-associated protein 1 | 0.0228747 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0228348 |
| VCL | vinculin | 0.0227499 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0224561 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0212705 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0208065 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0205923 |
| TPM3 | tropomyosin 3 | 0.020488 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.020025 |
| ABI1 | abl-interactor 1 | 0.0199894 |
| USP15 | ubiquitin specific peptidase 15 | 0.0192687 |
| NEK7 | NIMA-related kinase 7 | 0.0190748 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0185064 |
| APP | amyloid beta (A4) precursor protein | 0.0180289 |
| STK17A | serine/threonine kinase 17a | 0.0180058 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0176441 |
| STC1 | stanniocalcin 1 | 0.0171906 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0167312 |
| ZNF217 | zinc finger protein 217 | 0.0167256 |
| EMP1 | epithelial membrane protein 1 | 0.0165817 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0164256 |
| RBM33 | RNA binding motif protein 33 | 0.0163094 |
| PHF3 | PHD finger protein 3 | 0.0161147 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0157728 |
| TEX10 | testis expressed 10 | 0.0155199 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0155088 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0152916 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0152846 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0149503 |
| RHOA | ras homolog family member A | 0.0148072 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0148071 |
| RPS15A | ribosomal protein S15a | 0.0147325 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0146793 |
| RPL4 | ribosomal protein L4 | 0.0146404 |
| VGF | VGF nerve growth factor inducible | 0.0146312 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0146293 |
| BRD2 | bromodomain containing 2 | 0.0146104 |
| H1-4 | H1.4 linker histone, cluster member | 0.0145938 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0145132 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0144771 |
| CUL3 | cullin 3 | 0.0144374 |
| RPL3 | ribosomal protein L3 | 0.0143701 |
| NUP153 | nucleoporin 153kDa | 0.0142596 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0142274 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0141348 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0141197 |
| FLNA | filamin A, alpha | 0.014049 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0140267 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.013908 |
| TOP1 | topoisomerase (DNA) I | 0.0138027 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0135531 |
| MED13L | mediator complex subunit 13-like | 0.0135399 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0134899 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0134116 |
| CAPRIN2 | caprin family member 2 | 0.0133737 |
| PLIN2 | perilipin 2 | 0.0133261 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.013257 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0131533 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0130411 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0128273 |
| FLNB | filamin B, beta | 0.0128067 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.012694 |
| TXNRD1 | thioredoxin reductase 1 | 0.0126688 |
| CDYL2 | chromodomain protein, Y-like 2 | 0.012614 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0125614 |
| RYK | receptor-like tyrosine kinase | 0.0125428 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.012501 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0124965 |
| FMNL2 | formin-like 2 | 0.0124163 |
| LMNA | lamin A/C | 0.0124094 |
| RIOK3 | RIO kinase 3 | 0.0123862 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0123733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.360246 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.189653 |
| EFNA5 | ephrin-A5 | -0.154898 |
| MMP12 | matrix metallopeptidase 12 | -0.139583 |
| RPS6 | ribosomal protein S6 | -0.137999 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.131912 |
| DTNA | dystrobrevin, alpha | -0.130985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.126398 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.117456 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0962073 |
| CALD1 | caldesmon 1 | -0.0905896 |
| CDH13 | cadherin 13 | -0.085371 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0829902 |
| EGR1 | early growth response 1 | -0.0823671 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0811696 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0810213 |
| POTEF | POTE ankyrin domain family, member F | -0.0799233 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0788581 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0776778 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0704336 |
| LSAMP | limbic system-associated membrane protein | -0.0685195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0674351 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.064971 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0635615 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0628048 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.061956 |
| RUNX1 | runt-related transcription factor 1 | -0.059284 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0591569 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0590705 |
| NAV1 | neuron navigator 1 | -0.0586974 |
| ACTG1 | actin gamma 1 | -0.0583858 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0582494 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0558583 |
| TPM4 | tropomyosin 4 | -0.0525969 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.052422 |
| KIAA1217 | KIAA1217 | -0.0505652 |
| GPC6 | glypican 6 | -0.0489548 |
| MYO10 | myosin X | -0.0487002 |
| RPL35A | ribosomal protein L35a | -0.0472978 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0471598 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0470003 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0457135 |
| PRKCE | protein kinase C, epsilon | -0.041891 |
| HDAC9 | histone deacetylase 9 | -0.0418793 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0410703 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0407334 |
| FN1 | fibronectin 1 | -0.0399948 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0398009 |
| BPTF | bromodomain PHD finger transcription factor | -0.0386289 |
| JUN | jun proto-oncogene | -0.0386148 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0384162 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0382102 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0378084 |
| SBF2 | SET binding factor 2 | -0.036156 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0358427 |
| USP34 | ubiquitin specific peptidase 34 | -0.0356172 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0355554 |
| FOXP1 | forkhead box P1 | -0.0351395 |
| NDRG1 | N-myc downstream regulated 1 | -0.0344433 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0341828 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0338025 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0333982 |
| JMJD1C | jumonji domain containing 1C | -0.0329975 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0325193 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320711 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311895 |
| CDK6 | cyclin-dependent kinase 6 | -0.0308918 |
| KDM2B | lysine (K)-specific demethylase 2B | -0.0306843 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0301675 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0300065 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0299196 |
| MCL1 | myeloid cell leukemia 1 | -0.0297779 |
| RPL5 | ribosomal protein L5 | -0.0294754 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.029304 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0291436 |
| CUX1 | cut-like homeobox 1 | -0.0290759 |
| MAP4 | microtubule-associated protein 4 | -0.0290713 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0290548 |
| KIAA1549L | KIAA1549-like | -0.0289146 |
| RPS13 | ribosomal protein S13 | -0.0287883 |
| MKI67 | marker of proliferation Ki-67 | -0.0284499 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0284369 |
| RNF213 | ring finger protein 213 | -0.0280913 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.027676 |
| FOSL1 | FOS-like antigen 1 | -0.027398 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0271912 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270752 |
| RPLP1 | ribosomal protein, large, P1 | -0.0268448 |
| RPS8 | ribosomal protein S8 | -0.0267101 |
| MSR1 | macrophage scavenger receptor 1 | -0.0264734 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0263462 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0261952 |
| LIMA1 | LIM domain and actin binding 1 | -0.0260874 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0260278 |
| PTK2 | protein tyrosine kinase 2 | -0.0259845 |
| EGFR | epidermal growth factor receptor | -0.0259801 |
| ARFGEF3 | ARFGEF family member 3 | -0.0256218 |
| WWC1 | WW and C2 domain containing 1 | -0.0255234 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0254352 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0246338 |
