| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.110658 |
| TMSB10 | thymosin beta 10 | 0.100276 |
| RHOA | ras homolog family member A | 0.0701933 |
| EREG | epiregulin | 0.0699865 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0698577 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.069065 |
| MYO5B | myosin VB | 0.0685855 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0681639 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0656675 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0622596 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0585355 |
| RNF145 | ring finger protein 145 | 0.0559626 |
| KLF6 | Kruppel-like factor 6 | 0.0514941 |
| S100A6 | S100 calcium binding protein A6 | 0.051158 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0506597 |
| EZR | ezrin | 0.0470561 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0468622 |
| PARD3 | par-3 family cell polarity regulator | 0.040752 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0406919 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0401242 |
| RTN4 | reticulon 4 | 0.0392738 |
| ITGA6 | integrin, alpha 6 | 0.0392285 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.038416 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0380419 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0378095 |
| RPL35A | ribosomal protein L35a | 0.0376118 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0374793 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0346451 |
| XPO1 | exportin 1 | 0.033782 |
| TFG | TRK-fused gene | 0.0330971 |
| VEGFA | vascular endothelial growth factor A | 0.0330783 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0329659 |
| MAP4 | microtubule-associated protein 4 | 0.0325353 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0324537 |
| FNBP1L | formin binding protein 1-like | 0.0317309 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0314078 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0312141 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0304938 |
| NUP58 | nucleoporin 58 | 0.0303703 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0300165 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0295538 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0294943 |
| TFF1 | trefoil factor 1 | 0.0294876 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0292975 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0288614 |
| RHOB | ras homolog family member B | 0.0288227 |
| WDR43 | WD repeat domain 43 | 0.0285483 |
| RPL23 | ribosomal protein L23 | 0.028443 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0282353 |
| SVIL | supervillin | 0.0282001 |
| RYBP | RING1 and YY1 binding protein | 0.0281127 |
| COPA | coatomer protein complex, subunit alpha | 0.0278556 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0277064 |
| ABI1 | abl-interactor 1 | 0.0275238 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0274392 |
| RPL34 | ribosomal protein L34 | 0.0272635 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0270934 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0269393 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0268307 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0267989 |
| NCKAP1 | NCK-associated protein 1 | 0.0264303 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.026413 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0263207 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0262321 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0262155 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0258441 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0253723 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0252414 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0249706 |
| CCNL1 | cyclin L1 | 0.0248744 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.024685 |
| RBM39 | RNA binding motif protein 39 | 0.0245362 |
| SLMAP | sarcolemma associated protein | 0.0243989 |
| RPL3 | ribosomal protein L3 | 0.0242938 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0242514 |
| TMSB4X | thymosin beta 4, X-linked | 0.0241325 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0240121 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0235533 |
| CLIC4 | chloride intracellular channel 4 | 0.0233492 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0232585 |
| TPI1 | triosephosphate isomerase 1 | 0.0232427 |
| YTHDC1 | YTH domain containing 1 | 0.0230138 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0229668 |
| H2AC6 | H2A clustered histone 6 | 0.0229578 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0228126 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0225985 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0225616 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0225613 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.022235 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0221483 |
| HELZ | helicase with zinc finger | 0.0221469 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0221229 |
| CLDN12 | claudin 12 | 0.0220735 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0219868 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0219443 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0218991 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0218842 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0216216 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0213326 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0213271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.182169 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.173588 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.150666 |
| TNS4 | tensin 4 | -0.129016 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.117398 |
| ANTXR2 | anthrax toxin receptor 2 | -0.111203 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.108305 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104941 |
| CADPS | Ca++-dependent secretion activator | -0.100171 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0922928 |
| FLNB | filamin B, beta | -0.0903784 |
| RNF43 | ring finger protein 43 | -0.0875131 |
| ASPH | aspartate beta-hydroxylase | -0.076713 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0634527 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0597494 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0596637 |
| H1-0 | H1.0 linker histone | -0.0586735 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0572636 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0543509 |
| CANX | calnexin | -0.0528001 |
| SMYD3 | SET and MYND domain containing 3 | -0.0500906 |
| ACTN4 | actinin, alpha 4 | -0.0498118 |
| NPSR1 | neuropeptide S receptor 1 | -0.047859 |
| ONECUT3 | one cut homeobox 3 | -0.0477697 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0477129 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0465286 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0464599 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0460206 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0458246 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0449229 |
| ITGB4 | integrin, beta 4 | -0.0444251 |
| EHBP1 | EH domain binding protein 1 | -0.0443551 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0436448 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0424425 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0417867 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0414894 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0414318 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0402528 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0402354 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0395138 |
| NFIA | nuclear factor I/A | -0.0389535 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.038938 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0385933 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0383095 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0374865 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0372208 |
| LDHA | lactate dehydrogenase A | -0.0369367 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0368571 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0363796 |
| FERMT1 | fermitin family member 1 | -0.0363681 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.036096 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0355274 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0351431 |
| FHIT | fragile histidine triad | -0.0350001 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0345941 |
| METTL15 | methyltransferase like 15 | -0.0344885 |
| SHROOM3 | shroom family member 3 | -0.0344181 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.034116 |
| PCDHB16 | protocadherin beta 16 | -0.0337805 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0333485 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0331158 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0319414 |
| TRIM2 | tripartite motif containing 2 | -0.0314955 |
| PKP2 | plakophilin 2 | -0.0313224 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0312379 |
| EFNB2 | ephrin-B2 | -0.0311449 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.031051 |
| WWC1 | WW and C2 domain containing 1 | -0.0306577 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0305689 |
| MLEC | malectin | -0.0305413 |
| RRBP1 | ribosome binding protein 1 | -0.0301424 |
| EPHA2 | EPH receptor A2 | -0.0300349 |
| SERINC5 | serine incorporator 5 | -0.0298954 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0298609 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0293211 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0291192 |
| SCFD1 | sec1 family domain containing 1 | -0.0291151 |
| PRELID2 | PRELI domain containing 2 | -0.0289785 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0288772 |
| PATJ | PATJ crumbs cell polarity complex component | -0.028745 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.02834 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0280763 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0279833 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0277442 |
| ZNF638 | zinc finger protein 638 | -0.0276614 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0275152 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0269789 |
| MYO1E | myosin IE | -0.02675 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0265019 |
| KIAA0040 | KIAA0040 | -0.0264316 |
| NRXN3 | neurexin 3 | -0.0261199 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0258692 |
| RNF217 | ring finger protein 217 | -0.025822 |
| NOSTRIN | nitric oxide synthase trafficking | -0.0257649 |
| USO1 | USO1 vesicle transport factor | -0.0256968 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0254889 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0254748 |
| PIGR | polymeric immunoglobulin receptor | -0.0254357 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0253687 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0252774 |
