| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.105379 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0766303 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.067201 |
| RPL4 | ribosomal protein L4 | 0.0570665 |
| RPL3 | ribosomal protein L3 | 0.0567511 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0560817 |
| RPL13A | ribosomal protein L13a | 0.0560546 |
| RPS3 | ribosomal protein S3 | 0.05519 |
| RPS12 | ribosomal protein S12 | 0.0550949 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0512398 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0486907 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0477162 |
| PRELID2 | PRELI domain containing 2 | 0.0415828 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0379528 |
| RPL26 | ribosomal protein L26 | 0.0378668 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0362852 |
| RPS2 | ribosomal protein S2 | 0.0348308 |
| RPL23 | ribosomal protein L23 | 0.0342957 |
| ATXN1 | ataxin 1 | 0.0331744 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321691 |
| EREG | epiregulin | 0.0319586 |
| PTMA | prothymosin, alpha | 0.0318676 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0312217 |
| RNF145 | ring finger protein 145 | 0.0302532 |
| RPL12 | ribosomal protein L12 | 0.0299873 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0293015 |
| RPS8 | ribosomal protein S8 | 0.0291617 |
| RPL37A | ribosomal protein L37a | 0.0287862 |
| RPS17 | ribosomal protein S17 | 0.0281814 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0279194 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0276756 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0268254 |
| KLF6 | Kruppel-like factor 6 | 0.0256504 |
| RPL7 | ribosomal protein L7 | 0.0246262 |
| HMGB2 | high mobility group box 2 | 0.0242712 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0239967 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0232775 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.022467 |
| CCPG1 | cell cycle progression 1 | 0.0222319 |
| RPS19 | ribosomal protein S19 | 0.0221418 |
| RPLP1 | ribosomal protein, large, P1 | 0.022111 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0220696 |
| RPS27A | ribosomal protein S27a | 0.0215883 |
| RPL19 | ribosomal protein L19 | 0.0211198 |
| RPS15A | ribosomal protein S15a | 0.0209172 |
| OGA | O-GlcNAcase | 0.0205953 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0203149 |
| TXNRD1 | thioredoxin reductase 1 | 0.0199935 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0192263 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0190989 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0189665 |
| GDF15 | growth differentiation factor 15 | 0.0182844 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0181916 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.017858 |
| ENO1 | enolase 1, (alpha) | 0.0177332 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.017541 |
| HYOU1 | hypoxia up-regulated 1 | 0.0172952 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0171153 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0169093 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0167247 |
| RPSA | ribosomal protein SA | 0.0167066 |
| RPL5 | ribosomal protein L5 | 0.0165674 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0165235 |
| RPS27 | ribosomal protein S27 | 0.0163976 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0162932 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0160921 |
| CAMLG | calcium modulating ligand | 0.0158539 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.015809 |
| RPS5 | ribosomal protein S5 | 0.0157847 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0156313 |
| PHF3 | PHD finger protein 3 | 0.0155227 |
| XPOT | exportin, tRNA | 0.0154058 |
| KIF16B | kinesin family member 16B | 0.0150142 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0148276 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0146447 |
| RPL18 | ribosomal protein L18 | 0.0146288 |
| CANX | calnexin | 0.0143302 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0143154 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0142193 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0141667 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0141293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0141181 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0140238 |
| RPL9 | ribosomal protein L9 | 0.0135895 |
| H1-4 | H1.4 linker histone, cluster member | 0.0134507 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0134183 |
| RPS7 | ribosomal protein S7 | 0.013386 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.013291 |
| GOLGA4 | golgin A4 | 0.0131872 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.0131697 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0130495 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0130461 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.013027 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0129561 |
| SUCO | SUN domain containing ossification factor | 0.0129255 |
| RPL14 | ribosomal protein L14 | 0.012804 |
| RPS16 | ribosomal protein S16 | 0.0127767 |
| CDK19 | cyclin-dependent kinase 19 | 0.0126163 |
| SQSTM1 | sequestosome 1 | 0.0126055 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0125269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| THSD4 | thrombospondin, type I, domain containing 4 | -0.169252 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.143712 |
| FLNB | filamin B, beta | -0.121993 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.116264 |
| POTEF | POTE ankyrin domain family, member F | -0.0906576 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0880437 |
| MSI2 | musashi RNA-binding protein 2 | -0.0877452 |
| CALB1 | calbindin 1, 28kDa | -0.0834325 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0800501 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0704009 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0701524 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0681511 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0680935 |
| MYO1E | myosin IE | -0.0674289 |
| ANXA2 | annexin A2 | -0.0657887 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0651677 |
| LMO7 | LIM domain 7 | -0.0633594 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0600305 |
| MYOF | myoferlin | -0.0596932 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.057778 |
| MX1 | MX dynamin-like GTPase 1 | -0.0577598 |
| EZR | ezrin | -0.0575614 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0529801 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0529679 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0525295 |
| ACTG1 | actin gamma 1 | -0.0513618 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0504211 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0483569 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0464769 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0458973 |
| COBL | cordon-bleu WH2 repeat protein | -0.0441528 |
| PLAC8 | placenta-specific 8 | -0.0434071 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0430569 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0429048 |
| VCL | vinculin | -0.0428637 |
| CUX1 | cut-like homeobox 1 | -0.0425041 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.04154 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0407704 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0407035 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0406522 |
| OXSR1 | oxidative stress responsive 1 | -0.0402848 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0401773 |
| ACTN4 | actinin, alpha 4 | -0.0396932 |
| ITGB4 | integrin, beta 4 | -0.0396912 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0396108 |
| RNF213 | ring finger protein 213 | -0.039043 |
| PLSCR1 | phospholipid scramblase 1 | -0.0389743 |
| WWC1 | WW and C2 domain containing 1 | -0.0386234 |
| AOPEP | aminopeptidase O (putative) | -0.038575 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0385127 |
| FBXO11 | F-box protein 11 | -0.038313 |
| HLA-B | major histocompatibility complex, class I, B | -0.0366291 |
| SP100 | SP100 nuclear antigen | -0.0365374 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0355686 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0354289 |
| LAMA4 | laminin, alpha 4 | -0.0353442 |
| RIGI | RNA sensor RIG-I | -0.0352753 |
| PKM | pyruvate kinase, muscle | -0.0351779 |
| TCF12 | transcription factor 12 | -0.0351256 |
| SH3D19 | SH3 domain containing 19 | -0.0345141 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0341899 |
| RBM25 | RNA binding motif protein 25 | -0.0336574 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0332015 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0331937 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0331727 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0331368 |
| DSG3 | desmoglein 3 | -0.0329235 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0328782 |
| DIAPH1 | diaphanous-related formin 1 | -0.0322823 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0320789 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0319341 |
| TPM1 | tropomyosin 1 (alpha) | -0.0317996 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0317682 |
| BCL2L1 | BCL2-like 1 | -0.0312655 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0310969 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0310398 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0309316 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0307776 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0306181 |
| ITGA6 | integrin, alpha 6 | -0.0304854 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0304538 |
| PCBP2 | poly(rC) binding protein 2 | -0.0304244 |
| FOXP1 | forkhead box P1 | -0.0303255 |
| PALLD | palladin, cytoskeletal associated protein | -0.0302184 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0301146 |
| CDK6 | cyclin-dependent kinase 6 | -0.0291504 |
| RAD51B | RAD51 paralog B | -0.0290959 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0288777 |
| RPS21 | ribosomal protein S21 | -0.0287923 |
| DENND1A | DENN/MADD domain containing 1A | -0.0284422 |
| ANXA11 | annexin A11 | -0.0283501 |
| NPSR1 | neuropeptide S receptor 1 | -0.0280433 |
| FAT1 | FAT atypical cadherin 1 | -0.0280395 |
| SHROOM3 | shroom family member 3 | -0.0278798 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0278357 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0276302 |
| UBE3C | ubiquitin protein ligase E3C | -0.0275674 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.02754 |
| PERP | PERP, TP53 apoptosis effector | -0.0274883 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0274005 |
