| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.167468 |
| SPAG9 | sperm associated antigen 9 | 0.103908 |
| TP63 | tumor protein p63 | 0.101455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0782171 |
| ANXA1 | annexin A1 | 0.0520704 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0517994 |
| EZR | ezrin | 0.0467123 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0412114 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0382243 |
| EGFR | epidermal growth factor receptor | 0.0357503 |
| RHOA | ras homolog family member A | 0.0357382 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0349597 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0294362 |
| ABI1 | abl-interactor 1 | 0.0282693 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0260292 |
| COL5A2 | collagen, type V, alpha 2 | 0.0258396 |
| LYST | lysosomal trafficking regulator | 0.0251369 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0249037 |
| NCKAP1 | NCK-associated protein 1 | 0.0241764 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0230775 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0224824 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0215752 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0208716 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0205966 |
| MB21D2 | Mab-21 domain containing 2 | 0.0203363 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0202571 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0198999 |
| ETNK1 | ethanolamine kinase 1 | 0.019732 |
| NEK7 | NIMA-related kinase 7 | 0.0195091 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0188749 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0187382 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0185301 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0184314 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0184017 |
| DENND5A | DENN/MADD domain containing 5A | 0.0182746 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0178902 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0173722 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0171795 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0171018 |
| WAC | WW domain containing adaptor with coiled-coil | 0.016955 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0168466 |
| RAB18 | RAB18, member RAS oncogene family | 0.0166487 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.016514 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0163626 |
| RTN4 | reticulon 4 | 0.0162357 |
| MRTFA | myocardin related transcription factor A | 0.0155019 |
| WTAP | Wilms tumor 1 associated protein | 0.0154457 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0154221 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0153309 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0152859 |
| KLC1 | kinesin light chain 1 | 0.0152142 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0150413 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0148944 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0148101 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0146035 |
| CFB | complement factor B | 0.0145074 |
| FBXO42 | F-box protein 42 | 0.0144357 |
| GSN | gelsolin | 0.0144046 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0140303 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.01401 |
| KIF5B | kinesin family member 5B | 0.0138708 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0138407 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.013705 |
| DUSP16 | dual specificity phosphatase 16 | 0.0136785 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0136183 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0135434 |
| RAB10 | RAB10, member RAS oncogene family | 0.0133707 |
| ARRDC3 | arrestin domain containing 3 | 0.0132444 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0130366 |
| CUL3 | cullin 3 | 0.0128412 |
| SUCO | SUN domain containing ossification factor | 0.0127463 |
| ZNF451 | zinc finger protein 451 | 0.0127226 |
| TFG | TRK-fused gene | 0.012626 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0124688 |
| NUP58 | nucleoporin 58 | 0.0123244 |
| USP12 | ubiquitin specific peptidase 12 | 0.0120169 |
| ANK2 | ankyrin 2, neuronal | 0.011965 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0119259 |
| MYO6 | myosin VI | 0.0118488 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0117662 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0117651 |
| RPL3 | ribosomal protein L3 | 0.0117554 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0117434 |
| SERINC1 | serine incorporator 1 | 0.0116977 |
| OTUD7B | OTU deubiquitinase 7B | 0.0116399 |
| OGA | O-GlcNAcase | 0.0116241 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0116112 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0114747 |
| CRY1 | cryptochrome circadian clock 1 | 0.0114416 |
| JMJD1C | jumonji domain containing 1C | 0.0114295 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0114059 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0113028 |
| TAOK1 | TAO kinase 1 | 0.0112324 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.011218 |
| ATF3 | activating transcription factor 3 | 0.0111349 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0110645 |
| ECT2 | epithelial cell transforming 2 | 0.0110304 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0109902 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0109079 |
| ANLN | anillin, actin binding protein | 0.0108577 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.299807 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.201541 |
| MT2A | metallothionein 2A | -0.137103 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.104065 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.101608 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0976377 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0910935 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0832125 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0796962 |
| TMSB10 | thymosin beta 10 | -0.0796873 |
| CAPRIN2 | caprin family member 2 | -0.0767987 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0724123 |
| PTMA | prothymosin, alpha | -0.0718695 |
| CD44 | CD44 molecule (Indian blood group) | -0.0713864 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0699395 |
| RUNX1 | runt-related transcription factor 1 | -0.0697223 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0637894 |
| PDE10A | phosphodiesterase 10A | -0.0626571 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0623452 |
| FMNL2 | formin-like 2 | -0.0603536 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0589677 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0585225 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0579571 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0578193 |
| POTEF | POTE ankyrin domain family, member F | -0.0574808 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0566205 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0565373 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0559242 |
| EHBP1 | EH domain binding protein 1 | -0.0539861 |
| ACTG1 | actin gamma 1 | -0.0525686 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0519641 |
| TXNRD1 | thioredoxin reductase 1 | -0.051447 |
| EGR1 | early growth response 1 | -0.0486545 |
| HMGA1 | high mobility group AT-hook 1 | -0.0484619 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0484285 |
| DPYD | dihydropyrimidine dehydrogenase | -0.047742 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.047064 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0456007 |
| CADM2 | cell adhesion molecule 2 | -0.0451757 |
| RPS6 | ribosomal protein S6 | -0.0439815 |
| RPS8 | ribosomal protein S8 | -0.0428035 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.041301 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0406334 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0404107 |
| CMIP | c-Maf inducing protein | -0.0395711 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0394561 |
| FLNB | filamin B, beta | -0.0392397 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0389496 |
| MT1E | metallothionein 1E | -0.0386283 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0381763 |
| FTL | ferritin, light polypeptide | -0.0379783 |
| PYGL | phosphorylase, glycogen, liver | -0.0370749 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0362983 |
| HLA-B | major histocompatibility complex, class I, B | -0.0350812 |
| CDK6 | cyclin-dependent kinase 6 | -0.0349232 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0348372 |
| RPL12 | ribosomal protein L12 | -0.0343397 |
| ANGPTL4 | angiopoietin-like 4 | -0.0342285 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0336676 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0330376 |
| TXNIP | thioredoxin interacting protein | -0.0326562 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0322793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0320377 |
| PRELID2 | PRELI domain containing 2 | -0.0318648 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0317146 |
| RACK1 | receptor for activated C kinase 1 | -0.0315792 |
| RAI1 | retinoic acid induced 1 | -0.0314952 |
| LDHA | lactate dehydrogenase A | -0.0309042 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0308345 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0306809 |
| APP | amyloid beta (A4) precursor protein | -0.0306532 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0304766 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0304352 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0299829 |
| BPTF | bromodomain PHD finger transcription factor | -0.0299797 |
| RPS19 | ribosomal protein S19 | -0.0299644 |
| RPL35A | ribosomal protein L35a | -0.0297897 |
| RGS4 | regulator of G-protein signaling 4 | -0.0296093 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0294849 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0292958 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0289269 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0283456 |
| SRGN | serglycin | -0.0281275 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0279335 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027323 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0265296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0261937 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.02609 |
| RPL31 | ribosomal protein L31 | -0.0256965 |
| RNF213 | ring finger protein 213 | -0.0256714 |
| RPS12 | ribosomal protein S12 | -0.0252887 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0252468 |
| RPL37A | ribosomal protein L37a | -0.0252394 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0251941 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0249291 |
| MT1X | metallothionein 1X | -0.0248702 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0248057 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0244462 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0243091 |
| LOXL2 | lysyl oxidase-like 2 | -0.0243062 |
