| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.123447 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0574893 |
| ANKRD10 | ankyrin repeat domain 10 | 0.046593 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0396552 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.032318 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0315514 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0281298 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0281193 |
| MYO5B | myosin VB | 0.0279259 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0276302 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0272933 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0260842 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0251262 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0250959 |
| LMO7 | LIM domain 7 | 0.0248598 |
| PLEC | plectin | 0.0247601 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0247401 |
| TOP1 | topoisomerase (DNA) I | 0.024133 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.024029 |
| RNF145 | ring finger protein 145 | 0.0231724 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0229907 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0224846 |
| KLC1 | kinesin light chain 1 | 0.0224784 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0219266 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.021766 |
| NUP58 | nucleoporin 58 | 0.0214922 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0212007 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0210658 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0210386 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0208546 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0206254 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0205346 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0196803 |
| ARRDC3 | arrestin domain containing 3 | 0.0194562 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0193496 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0192364 |
| RPL3 | ribosomal protein L3 | 0.0184386 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0182856 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0181467 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0178281 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0177963 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0177055 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | 0.0173842 |
| NCKAP1 | NCK-associated protein 1 | 0.0173725 |
| DENND4A | DENN/MADD domain containing 4A | 0.0173298 |
| FNIP1 | folliculin interacting protein 1 | 0.0173181 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0171307 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0169801 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0168407 |
| GPC5 | glypican 5 | 0.0166572 |
| RTN4 | reticulon 4 | 0.0165367 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0162449 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0162282 |
| NTN4 | netrin 4 | 0.0162176 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0160233 |
| SETD3 | SET domain containing 3 | 0.0156391 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0155784 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0155633 |
| CASC3 | cancer susceptibility candidate 3 | 0.0153908 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0153871 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0152722 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0152193 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0152094 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0151291 |
| RHOA | ras homolog family member A | 0.0150715 |
| RBM33 | RNA binding motif protein 33 | 0.0150511 |
| MED13L | mediator complex subunit 13-like | 0.0148833 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0145798 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0145402 |
| PGK1 | phosphoglycerate kinase 1 | 0.0144457 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.0143446 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0143209 |
| JAK1 | Janus kinase 1 | 0.0142026 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0141772 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0140703 |
| SPAG9 | sperm associated antigen 9 | 0.0140302 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0139981 |
| MATR3 | matrin 3 | 0.0137766 |
| WDR49 | WD repeat domain 49 | 0.0135953 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0133855 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0133801 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0133265 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0133024 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0132559 |
| FAT1 | FAT atypical cadherin 1 | 0.0132471 |
| USP12 | ubiquitin specific peptidase 12 | 0.0128547 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0128078 |
| PCBP3 | poly(rC) binding protein 3 | 0.0127876 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0126501 |
| MRTFA | myocardin related transcription factor A | 0.0124743 |
| OGA | O-GlcNAcase | 0.0124215 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0124083 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0122365 |
| ACVR1 | activin A receptor, type I | 0.0120975 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0120371 |
| ATG14 | autophagy related 14 | 0.0119959 |
| CUL3 | cullin 3 | 0.0119932 |
| HYOU1 | hypoxia up-regulated 1 | 0.0119774 |
| RPL4 | ribosomal protein L4 | 0.0119607 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0118711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.508544 |
| EGFR | epidermal growth factor receptor | -0.3007 |
| NDRG1 | N-myc downstream regulated 1 | -0.145067 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0976009 |
| MT2A | metallothionein 2A | -0.0917386 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0892348 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0881697 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0824163 |
| LAMC2 | laminin, gamma 2 | -0.0716275 |
| STC1 | stanniocalcin 1 | -0.0704299 |
| EGR1 | early growth response 1 | -0.0697161 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.067607 |
| S100A10 | S100 calcium binding protein A10 | -0.0652979 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.064045 |
| MCL1 | myeloid cell leukemia 1 | -0.0605649 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0599157 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0594968 |
| ACTG1 | actin gamma 1 | -0.0562736 |
| TMSB10 | thymosin beta 10 | -0.0551182 |
| LAMA4 | laminin, alpha 4 | -0.0550475 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.052728 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0525511 |
| PKM | pyruvate kinase, muscle | -0.0512083 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0509938 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0500253 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0500135 |
| LDHA | lactate dehydrogenase A | -0.0496662 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0493276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0492747 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0470755 |
| EFNA5 | ephrin-A5 | -0.0455322 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.045474 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0450338 |
| CDCP1 | CUB domain containing protein 1 | -0.0437694 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0432776 |
| ANXA2 | annexin A2 | -0.0418193 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0407792 |
| UBC | ubiquitin C | -0.0403433 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.038238 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0362519 |
| FTL | ferritin, light polypeptide | -0.0361025 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0356437 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0355942 |
| SEC61G | Sec61 gamma subunit | -0.0346866 |
| SLTM | SAFB-like, transcription modulator | -0.03423 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0337853 |
| MYO1E | myosin IE | -0.0334163 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.033102 |
| RNF213 | ring finger protein 213 | -0.0328363 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0327895 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0324125 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0320583 |
| MORF4L2 | mortality factor 4 like 2 | -0.0319665 |
| POTEF | POTE ankyrin domain family, member F | -0.0319325 |
| OSMR | oncostatin M receptor | -0.0313426 |
| ASPH | aspartate beta-hydroxylase | -0.0309546 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0306587 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0304959 |
| GOLGB1 | golgin B1 | -0.0304877 |
| ENO1 | enolase 1, (alpha) | -0.0300665 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0290764 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290348 |
| INTS6 | integrator complex subunit 6 | -0.0289751 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0282431 |
| PTMA | prothymosin, alpha | -0.0281912 |
| FOXP1 | forkhead box P1 | -0.0281313 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0280788 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0280269 |
| VCL | vinculin | -0.027794 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0274371 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0270814 |
| SP100 | SP100 nuclear antigen | -0.0270593 |
| BPTF | bromodomain PHD finger transcription factor | -0.0258287 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0253691 |
| RPS6 | ribosomal protein S6 | -0.0248752 |
| CST3 | cystatin C | -0.0247209 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0246326 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0245556 |
| FAM13A | family with sequence similarity 13, member A | -0.0243719 |
| PYGL | phosphorylase, glycogen, liver | -0.0243713 |
| CD163L1 | CD163 molecule-like 1 | -0.0243076 |
| MT1X | metallothionein 1X | -0.0242082 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0239971 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0235289 |
| ZNF638 | zinc finger protein 638 | -0.0234802 |
| CSNK1E | casein kinase 1, epsilon | -0.0234642 |
| SCEL | sciellin | -0.0231786 |
| EMP1 | epithelial membrane protein 1 | -0.0229911 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.0229733 |
| ENSA | endosulfine alpha | -0.0228507 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.022608 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0225019 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0224241 |
| ARF4 | ADP-ribosylation factor 4 | -0.0223606 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0223152 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0221336 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.022033 |
| CSTB | cystatin B (stefin B) | -0.0218873 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0218436 |
| IER3 | immediate early response 3 | -0.021773 |
