| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 0.187386 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.101695 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0756284 |
| SPAG9 | sperm associated antigen 9 | 0.0730795 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0723135 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0720009 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0661011 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0612183 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0526314 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0502815 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0490417 |
| KLF6 | Kruppel-like factor 6 | 0.0483534 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0460034 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0459493 |
| ATP13A3 | ATPase type 13A3 | 0.0449693 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0438091 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437991 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0407338 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0393082 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0387733 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.038265 |
| ANXA1 | annexin A1 | 0.037278 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0371982 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0363256 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0362332 |
| AHNAK | AHNAK nucleoprotein | 0.0358856 |
| ANXA2 | annexin A2 | 0.0358771 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0356161 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0349068 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0348859 |
| FAM13A | family with sequence similarity 13, member A | 0.034022 |
| USP3 | ubiquitin specific peptidase 3 | 0.0332926 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0332151 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0331781 |
| OGA | O-GlcNAcase | 0.0327464 |
| ABI1 | abl-interactor 1 | 0.0326821 |
| EZR | ezrin | 0.0325717 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.032279 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0322333 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.032055 |
| SMAD3 | SMAD family member 3 | 0.0316667 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0316345 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0313811 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0300058 |
| RBM39 | RNA binding motif protein 39 | 0.0298964 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0296986 |
| STC1 | stanniocalcin 1 | 0.0296152 |
| RAI14 | retinoic acid induced 14 | 0.0290051 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0285339 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.028178 |
| SNX9 | sorting nexin 9 | 0.027948 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0278721 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0277849 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0274259 |
| SIK3 | SIK family kinase 3 | 0.0272056 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.027115 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0264742 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0263635 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.026237 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0262171 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0261032 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0260826 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0259169 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0257171 |
| CCNY | cyclin Y | 0.0256801 |
| PTK2 | protein tyrosine kinase 2 | 0.0251915 |
| OXSR1 | oxidative stress responsive 1 | 0.0251638 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.025135 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248193 |
| MYO1E | myosin IE | 0.0246936 |
| RUNX2 | runt-related transcription factor 2 | 0.0246228 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0245337 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0244962 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0244598 |
| FAM107B | family with sequence similarity 107, member B | 0.0244343 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0242856 |
| NPC1 | Niemann-Pick disease, type C1 | 0.024153 |
| MAP4 | microtubule-associated protein 4 | 0.0238968 |
| APP | amyloid beta (A4) precursor protein | 0.023584 |
| RHOA | ras homolog family member A | 0.023504 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0234498 |
| EREG | epiregulin | 0.0234425 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0232218 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0229215 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0229175 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0226079 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.02258 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0225429 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0223154 |
| RASA2 | RAS p21 protein activator 2 | 0.0222413 |
| CDC73 | cell division cycle 73 | 0.0220358 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0219102 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0218503 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0217761 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0217592 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0215502 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0215302 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0214995 |
| USP12 | ubiquitin specific peptidase 12 | 0.021355 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0211685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.165027 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.107766 |
| DPYD | dihydropyrimidine dehydrogenase | -0.101847 |
| VIM | vimentin | -0.0870016 |
| GPC6 | glypican 6 | -0.0757131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0731085 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0730758 |
| HMGA2 | high mobility group AT-hook 2 | -0.07111 |
| EGR1 | early growth response 1 | -0.0634675 |
| FN1 | fibronectin 1 | -0.0611829 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0596291 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0548979 |
| LOX | lysyl oxidase | -0.0518408 |
| EFNA5 | ephrin-A5 | -0.051071 |
| EHBP1 | EH domain binding protein 1 | -0.0501558 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.049423 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0484263 |
| CDH13 | cadherin 13 | -0.0482089 |
| NRG1 | neuregulin 1 | -0.0481221 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0460536 |
| NRP1 | neuropilin 1 | -0.0446245 |
| RAD51B | RAD51 paralog B | -0.0429436 |
| SYT1 | synaptotagmin I | -0.0407767 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0402428 |
| MECOM | MDS1 and EVI1 complex locus | -0.0398569 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0397672 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0395919 |
| USP34 | ubiquitin specific peptidase 34 | -0.0376533 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0375586 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0372635 |
| EXOC4 | exocyst complex component 4 | -0.0371305 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.035771 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0334176 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0324842 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0324499 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0319756 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0319052 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.03172 |
| POTEF | POTE ankyrin domain family, member F | -0.031598 |
| MCL1 | myeloid cell leukemia 1 | -0.0314314 |
| ATF7 | activating transcription factor 7 | -0.0312837 |
| FTL | ferritin, light polypeptide | -0.030999 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0309534 |
| MT2A | metallothionein 2A | -0.0306349 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0299772 |
| HMGA1 | high mobility group AT-hook 1 | -0.0298669 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0297224 |
| EGFR | epidermal growth factor receptor | -0.0296979 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0294962 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0293473 |
| PRKCA | protein kinase C, alpha | -0.0292722 |
| NDRG1 | N-myc downstream regulated 1 | -0.0292484 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0292281 |
| RPS19 | ribosomal protein S19 | -0.0292038 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0286004 |
| PCBP2 | poly(rC) binding protein 2 | -0.0283847 |
| GLCCI1 | glucocorticoid induced 1 | -0.0282905 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0278034 |
| NAV3 | neuron navigator 3 | -0.0275645 |
| DST | dystonin | -0.027546 |
| PHF21A | PHD finger protein 21A | -0.0265863 |
| ETV6 | ets variant 6 | -0.0265 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0263827 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0263736 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0255719 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.025394 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0252966 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0250627 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0248387 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.024174 |
| ASPH | aspartate beta-hydroxylase | -0.0241571 |
| B2M | beta-2-microglobulin | -0.023673 |
| BPTF | bromodomain PHD finger transcription factor | -0.023086 |
| MX2 | MX dynamin-like GTPase 2 | -0.0230127 |
| RNF213 | ring finger protein 213 | -0.0227285 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0224581 |
| OSMR | oncostatin M receptor | -0.0224506 |
| MYADM | myeloid-associated differentiation marker | -0.0223889 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0222186 |
| TGFB1 | transforming growth factor, beta 1 | -0.0220403 |
| FAM20C | family with sequence similarity 20, member C | -0.0220356 |
| SUMF1 | sulfatase modifying factor 1 | -0.0219224 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0218662 |
| TMSB10 | thymosin beta 10 | -0.0215575 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0213808 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0213742 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0212976 |
| RGS17 | regulator of G-protein signaling 17 | -0.0212841 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0212643 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0212145 |
| SYAP1 | synapse associated protein 1 | -0.0211649 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0211294 |
| ZNF804A | zinc finger protein 804A | -0.0209425 |
| AADAC | arylacetamide deacetylase | -0.0204984 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0203771 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0203175 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0202452 |
| ATG7 | autophagy related 7 | -0.0201708 |
| ANKRD17 | ankyrin repeat domain 17 | -0.019914 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0196736 |
