| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.096655 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0875883 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0790372 |
| TMSB10 | thymosin beta 10 | 0.0638005 |
| FN1 | fibronectin 1 | 0.0606238 |
| KRT17 | keratin 17, type I | 0.0542511 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0519632 |
| STC1 | stanniocalcin 1 | 0.0481986 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0480894 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0474081 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0439274 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0427142 |
| AREG | amphiregulin | 0.0421875 |
| CDH13 | cadherin 13 | 0.0413624 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0407406 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0397725 |
| NAV2 | neuron navigator 2 | 0.0395724 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.038906 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0385388 |
| TMEM165 | transmembrane protein 165 | 0.0381942 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0381411 |
| ACTG1 | actin gamma 1 | 0.0366044 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.036414 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0355952 |
| PKM | pyruvate kinase, muscle | 0.0353739 |
| LAMB3 | laminin, beta 3 | 0.0350769 |
| SLMAP | sarcolemma associated protein | 0.0345753 |
| CDK13 | cyclin-dependent kinase 13 | 0.0345071 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.034321 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | 0.0338836 |
| RPS25 | ribosomal protein S25 | 0.0338569 |
| SQSTM1 | sequestosome 1 | 0.0332172 |
| SVIL | supervillin | 0.0328084 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0325579 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0325485 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0324075 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.031727 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0316911 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0316105 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0314096 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0311911 |
| RPS17 | ribosomal protein S17 | 0.0305891 |
| RPL37 | ribosomal protein L37 | 0.0305146 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0303714 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0301946 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.0301412 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0298723 |
| TOP1 | topoisomerase (DNA) I | 0.0297112 |
| FLNB | filamin B, beta | 0.029669 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0296444 |
| ARRDC3 | arrestin domain containing 3 | 0.029407 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.029395 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0292168 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0286376 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0280043 |
| RPS3 | ribosomal protein S3 | 0.0277809 |
| MAP7 | microtubule-associated protein 7 | 0.0274542 |
| RPL11 | ribosomal protein L11 | 0.027431 |
| VIM | vimentin | 0.0270688 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0268368 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0264891 |
| RPLP0 | ribosomal protein, large, P0 | 0.0264124 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0263488 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0262741 |
| FAM13A | family with sequence similarity 13, member A | 0.0261166 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0259912 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0258884 |
| IL1A | interleukin 1, alpha | 0.0258672 |
| NUP58 | nucleoporin 58 | 0.0258525 |
| WWC1 | WW and C2 domain containing 1 | 0.0257626 |
| RPS8 | ribosomal protein S8 | 0.0257566 |
| INHBA | inhibin, beta A | 0.0256694 |
| RPS19 | ribosomal protein S19 | 0.0253848 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0253161 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0250766 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0248746 |
| RPS11 | ribosomal protein S11 | 0.0247352 |
| HMGA1 | high mobility group AT-hook 1 | 0.024657 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0245357 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0244767 |
| RPL31 | ribosomal protein L31 | 0.024448 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0242392 |
| USP53 | ubiquitin specific peptidase 53 | 0.0242225 |
| TMSB4X | thymosin beta 4, X-linked | 0.0241721 |
| PTMA | prothymosin, alpha | 0.0241446 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0238974 |
| MYO6 | myosin VI | 0.0237725 |
| NEK7 | NIMA-related kinase 7 | 0.023747 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0236786 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0236565 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0236556 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0235051 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0234032 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0233721 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.023209 |
| NKTR | natural killer cell triggering receptor | 0.0232041 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0231995 |
| KLF12 | Kruppel-like factor 12 | 0.0231784 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0231225 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0230834 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.143787 |
| KYNU | kynureninase | -0.0855725 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.085353 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0845113 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0725544 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0642296 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.062225 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0596268 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.059601 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.058395 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0534573 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0533375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0522616 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0506657 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0504208 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0492757 |
| IGF2 | insulin-like growth factor 2 | -0.0488289 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0487023 |
| FMN1 | formin 1 | -0.0476244 |
| OSMR | oncostatin M receptor | -0.0471462 |
| MYO1E | myosin IE | -0.046721 |
| RIGI | RNA sensor RIG-I | -0.0465077 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.044956 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0448615 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0429699 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0425164 |
| RAD51B | RAD51 paralog B | -0.0407954 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0395794 |
| RTN4 | reticulon 4 | -0.0394318 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0394055 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0390841 |
| ACTN4 | actinin, alpha 4 | -0.0389011 |
| EXOC6B | exocyst complex component 6B | -0.038689 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0379704 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.037848 |
| USP34 | ubiquitin specific peptidase 34 | -0.0373576 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0372599 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.036839 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0367099 |
| ANO6 | anoctamin 6 | -0.0359393 |
| VCL | vinculin | -0.0357516 |
| SP100 | SP100 nuclear antigen | -0.0355401 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0353138 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0345344 |
| PARD3 | par-3 family cell polarity regulator | -0.0341466 |
| PCBP2 | poly(rC) binding protein 2 | -0.0333627 |
| NPTN | neuroplastin | -0.0332985 |
| ANXA1 | annexin A1 | -0.0322717 |
| RORA | RAR-related orphan receptor A | -0.0320783 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0312197 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0306991 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0306617 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0300521 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0287617 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284517 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0281347 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0280412 |
| ZNF207 | zinc finger protein 207 | -0.0279437 |
| WDR26 | WD repeat domain 26 | -0.0276382 |
| CANX | calnexin | -0.0275466 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0275087 |
| FTL | ferritin, light polypeptide | -0.0273488 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0273001 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0271613 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0268241 |
| ABI1 | abl-interactor 1 | -0.0266733 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0261678 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0260499 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0257959 |
| MXD1 | MAX dimerization protein 1 | -0.0256957 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.025407 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0253219 |
| BPTF | bromodomain PHD finger transcription factor | -0.0250663 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0250142 |
| SMYD3 | SET and MYND domain containing 3 | -0.0249819 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0248761 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0248644 |
| SBF2 | SET binding factor 2 | -0.0248601 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0247165 |
| GOLGA4 | golgin A4 | -0.0244629 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0243291 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0241343 |
| INTS6 | integrator complex subunit 6 | -0.024103 |
| FOSL2 | FOS-like antigen 2 | -0.023656 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0236102 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0234535 |
| TAOK3 | TAO kinase 3 | -0.022718 |
| DENND1A | DENN/MADD domain containing 1A | -0.0224478 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0222197 |
| RNF24 | ring finger protein 24 | -0.0220696 |
| GPATCH2L | G patch domain containing 2-like | -0.0219959 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0219399 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.021873 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0217716 |
| TNRC18 | trinucleotide repeat containing 18 | -0.021554 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.0214598 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0212129 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0211516 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0209766 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0206005 |
