| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.21056 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140408 |
| FNDC3B | fibronectin type III domain containing 3B | 0.124655 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.111469 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.101261 |
| ASPH | aspartate beta-hydroxylase | 0.100718 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0780942 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0742588 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0692099 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0675132 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0646319 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.056663 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0554094 |
| TFG | TRK-fused gene | 0.054119 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.050922 |
| LAMC2 | laminin, gamma 2 | 0.0499773 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0496957 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0493855 |
| NAV2 | neuron navigator 2 | 0.0492291 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0477325 |
| HMGB2 | high mobility group box 2 | 0.0474896 |
| APP | amyloid beta (A4) precursor protein | 0.045034 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0448113 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0446911 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0444453 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.043297 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0423375 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0422768 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0411342 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0409085 |
| PARD3 | par-3 family cell polarity regulator | 0.0405659 |
| RHEB | Ras homolog enriched in brain | 0.040335 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0399817 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0390931 |
| NCKAP1 | NCK-associated protein 1 | 0.0388149 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0377935 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.037348 |
| PLEC | plectin | 0.0369108 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0362015 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0356508 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0345198 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0345022 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0334618 |
| LMO7 | LIM domain 7 | 0.0333305 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0328236 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.032696 |
| RPL4 | ribosomal protein L4 | 0.0325279 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0321247 |
| TXNRD1 | thioredoxin reductase 1 | 0.0318812 |
| PAPOLA | poly(A) polymerase alpha | 0.0311893 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0311541 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.031104 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0309549 |
| ECT2 | epithelial cell transforming 2 | 0.0306532 |
| FHIT | fragile histidine triad | 0.0301706 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0299312 |
| PGK1 | phosphoglycerate kinase 1 | 0.0297408 |
| KLF6 | Kruppel-like factor 6 | 0.0293992 |
| ENO1 | enolase 1, (alpha) | 0.0293236 |
| PTK2 | protein tyrosine kinase 2 | 0.0290928 |
| MSN | moesin | 0.0288205 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0287822 |
| DSPP | dentin sialophosphoprotein | 0.0287506 |
| TMEM131L | transmembrane 131 like | 0.0284258 |
| PEG10 | paternally expressed 10 | 0.0275223 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0271862 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0271351 |
| RPL3 | ribosomal protein L3 | 0.026952 |
| MYOF | myoferlin | 0.0267756 |
| SMAD3 | SMAD family member 3 | 0.0262239 |
| AHNAK | AHNAK nucleoprotein | 0.026149 |
| CPNE8 | copine VIII | 0.0255227 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0255196 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0254939 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0254817 |
| ANLN | anillin, actin binding protein | 0.0249208 |
| ANXA1 | annexin A1 | 0.0248709 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0247686 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0247375 |
| CCNL1 | cyclin L1 | 0.0244401 |
| CALR | calreticulin | 0.0244348 |
| EZR | ezrin | 0.0236439 |
| RHOA | ras homolog family member A | 0.0234982 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0233939 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.023209 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0230369 |
| RPSA | ribosomal protein SA | 0.02277 |
| DENND4A | DENN/MADD domain containing 4A | 0.0225498 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0225154 |
| H1-4 | H1.4 linker histone, cluster member | 0.0223913 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0223687 |
| NPTN | neuroplastin | 0.0223381 |
| RUNX1 | runt-related transcription factor 1 | 0.0220378 |
| ARRDC3 | arrestin domain containing 3 | 0.021808 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0216759 |
| LRRC1 | leucine rich repeat containing 1 | 0.0213805 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0208857 |
| MORF4L1 | mortality factor 4 like 1 | 0.0207758 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0206028 |
| ANXA5 | annexin A5 | 0.0205563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.224853 |
| POTEF | POTE ankyrin domain family, member F | -0.215762 |
| ACTG1 | actin gamma 1 | -0.194113 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.153098 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150409 |
| PTMA | prothymosin, alpha | -0.076381 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0695274 |
| RPL35A | ribosomal protein L35a | -0.0634046 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0632727 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0627003 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0624857 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0613717 |
| CSTB | cystatin B (stefin B) | -0.0608451 |
| RBM25 | RNA binding motif protein 25 | -0.0584802 |
| TPM4 | tropomyosin 4 | -0.0576028 |
| RPLP1 | ribosomal protein, large, P1 | -0.0565561 |
| TMSB10 | thymosin beta 10 | -0.0553484 |
| HLA-B | major histocompatibility complex, class I, B | -0.0536114 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0520404 |
| DTNA | dystrobrevin, alpha | -0.0506828 |
| HMGA1 | high mobility group AT-hook 1 | -0.0465752 |
| S100A6 | S100 calcium binding protein A6 | -0.0455653 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0444556 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0444083 |
| HLA-A | major histocompatibility complex, class I, A | -0.0430741 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0421732 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0420461 |
| FBXO32 | F-box protein 32 | -0.0407345 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0404041 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0400822 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0399413 |
| RCOR1 | REST corepressor 1 | -0.039711 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.039347 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0391574 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0390621 |
| RPS8 | ribosomal protein S8 | -0.0381359 |
| RPL8 | ribosomal protein L8 | -0.0376415 |
| RPL9 | ribosomal protein L9 | -0.036094 |
| FOSL1 | FOS-like antigen 1 | -0.0357541 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0356805 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0354998 |
| BBX | bobby sox homolog (Drosophila) | -0.0354469 |
| VEGFA | vascular endothelial growth factor A | -0.035325 |
| RPS6 | ribosomal protein S6 | -0.0351914 |
| S100A10 | S100 calcium binding protein A10 | -0.034969 |
| S100A9 | S100 calcium binding protein A9 | -0.0347665 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0346404 |
| GOLGB1 | golgin B1 | -0.0342991 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0339045 |
| RPS13 | ribosomal protein S13 | -0.0338376 |
| CCND1 | cyclin D1 | -0.0336274 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0331517 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0330763 |
| RPS23 | ribosomal protein S23 | -0.0328181 |
| FBXO11 | F-box protein 11 | -0.0324348 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0323712 |
| EGR1 | early growth response 1 | -0.0320253 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0312021 |
| GOLGA4 | golgin A4 | -0.0308666 |
| JUP | junction plakoglobin | -0.0306778 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0306221 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0305411 |
| RPS29 | ribosomal protein S29 | -0.0304716 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0304555 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0304482 |
| GNAS | GNAS complex locus | -0.0301604 |
| ARF4 | ADP-ribosylation factor 4 | -0.0301192 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0300809 |
| RPS19 | ribosomal protein S19 | -0.0300615 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0299014 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0297274 |
| RPLP2 | ribosomal protein, large, P2 | -0.0297052 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0293368 |
| YY1 | YY1 transcription factor | -0.0293322 |
| G0S2 | G0/G1 switch 2 | -0.028772 |
| MT2A | metallothionein 2A | -0.0286834 |
| VIM | vimentin | -0.0285839 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0285725 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0283438 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.027306 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0272911 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0272076 |
| RAI14 | retinoic acid induced 14 | -0.0271898 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.027167 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0268466 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.026658 |
| ERBIN | erbb2 interacting protein | -0.0265954 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0264627 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0260229 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0257649 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0257478 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0255298 |
| CLDN4 | claudin 4 | -0.0251659 |
| WASF2 | WAS protein family, member 2 | -0.0249754 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0248319 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0247227 |
| RPL28 | ribosomal protein L28 | -0.0246984 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0243836 |
| TOP1 | topoisomerase (DNA) I | -0.0241142 |
| RPS12 | ribosomal protein S12 | -0.0238982 |
