| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.290149 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.093332 |
| ASPH | aspartate beta-hydroxylase | 0.0897254 |
| FN1 | fibronectin 1 | 0.0843383 |
| SPAG9 | sperm associated antigen 9 | 0.0781812 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0701462 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0677154 |
| PCBP3 | poly(rC) binding protein 3 | 0.0649348 |
| RGS2 | regulator of G-protein signaling 2 | 0.0601435 |
| STC1 | stanniocalcin 1 | 0.0589866 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0571706 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0562894 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0562753 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.055047 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0537847 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.051428 |
| NRCAM | neuronal cell adhesion molecule | 0.0501913 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0496948 |
| ANXA1 | annexin A1 | 0.0490858 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0475226 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0460832 |
| INHBA | inhibin, beta A | 0.0449772 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0427646 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0424988 |
| LMNA | lamin A/C | 0.0410166 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0403106 |
| TPI1 | triosephosphate isomerase 1 | 0.0402221 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.038966 |
| PTMA | prothymosin, alpha | 0.038479 |
| ENO1 | enolase 1, (alpha) | 0.037685 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0366023 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0364113 |
| CD109 | CD109 molecule | 0.0363746 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0360739 |
| LDHA | lactate dehydrogenase A | 0.0356323 |
| PGK1 | phosphoglycerate kinase 1 | 0.0352428 |
| ANXA2 | annexin A2 | 0.0344289 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0343847 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.034258 |
| TMSB4X | thymosin beta 4, X-linked | 0.0336549 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0329846 |
| NEFL | neurofilament, light polypeptide | 0.030398 |
| TPM3 | tropomyosin 3 | 0.0302465 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295346 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0293131 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0291293 |
| RIGI | RNA sensor RIG-I | 0.0289251 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0281488 |
| PRSS23 | protease, serine, 23 | 0.0278648 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0264816 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0250256 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0249102 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0239522 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0235678 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0233157 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0233048 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0231742 |
| RPL3 | ribosomal protein L3 | 0.022903 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.022509 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220585 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0218937 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211028 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0209387 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0209139 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0206723 |
| SET | SET nuclear proto-oncogene | 0.0204909 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0203255 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.020219 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0199826 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0197739 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0195839 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0195043 |
| RPL4 | ribosomal protein L4 | 0.0193956 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0191265 |
| RHOB | ras homolog family member B | 0.0190097 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.0183344 |
| B2M | beta-2-microglobulin | 0.0181922 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0180036 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0178669 |
| ETV3 | ets variant 3 | 0.0176643 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0175824 |
| KLF6 | Kruppel-like factor 6 | 0.017514 |
| GNAS | GNAS complex locus | 0.0174209 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0172668 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0172487 |
| NRG1 | neuregulin 1 | 0.0171732 |
| PLEC | plectin | 0.016922 |
| PRKD3 | protein kinase D3 | 0.0167812 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0165298 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0165109 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0164977 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0161944 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0158919 |
| ANGPTL4 | angiopoietin-like 4 | 0.0157937 |
| FLNB | filamin B, beta | 0.0156518 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0156352 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0156278 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0155295 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0155114 |
| SERINC1 | serine incorporator 1 | 0.0150786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2442 |
| EFNA5 | ephrin-A5 | -0.148302 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.116279 |
| RPS6 | ribosomal protein S6 | -0.0993602 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0930481 |
| RPS23 | ribosomal protein S23 | -0.0888926 |
| PDE10A | phosphodiesterase 10A | -0.0854452 |
| MT2A | metallothionein 2A | -0.0732493 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0685142 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0669995 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0665091 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0657875 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0639222 |
| RPS19 | ribosomal protein S19 | -0.0619838 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0618826 |
| RPLP1 | ribosomal protein, large, P1 | -0.0609817 |
| GDA | guanine deaminase | -0.0606445 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0571289 |
| SMYD3 | SET and MYND domain containing 3 | -0.0569146 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0553239 |
| FTL | ferritin, light polypeptide | -0.0544369 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.052881 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0526579 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0500305 |
| RPS29 | ribosomal protein S29 | -0.0490279 |
| TXNRD1 | thioredoxin reductase 1 | -0.0487572 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0471306 |
| AUTS2 | autism susceptibility candidate 2 | -0.0467035 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.045794 |
| DST | dystonin | -0.0456838 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0449887 |
| PTEN | phosphatase and tensin homolog | -0.0443441 |
| VIM | vimentin | -0.0430584 |
| RAD51B | RAD51 paralog B | -0.0406621 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0399556 |
| JMJD1C | jumonji domain containing 1C | -0.038908 |
| RPL28 | ribosomal protein L28 | -0.0389045 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0386754 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0380398 |
| RPS27 | ribosomal protein S27 | -0.037956 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0371503 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0363045 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0362873 |
| ASTN2 | astrotactin 2 | -0.0361887 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0361416 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0358857 |
| RPL36 | ribosomal protein L36 | -0.0355632 |
| CADM2 | cell adhesion molecule 2 | -0.0351955 |
| RPLP2 | ribosomal protein, large, P2 | -0.0351088 |
| MFF | mitochondrial fission factor | -0.0349786 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0348823 |
| RPL35A | ribosomal protein L35a | -0.0348402 |
| RPS21 | ribosomal protein S21 | -0.0344917 |
| RPL36A | ribosomal protein L36a | -0.0342461 |
| POTEF | POTE ankyrin domain family, member F | -0.0340581 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0338758 |
| CUX1 | cut-like homeobox 1 | -0.0337697 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0336468 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0334993 |
| RPL31 | ribosomal protein L31 | -0.033302 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0331736 |
| CDH13 | cadherin 13 | -0.0327055 |
| RPS14 | ribosomal protein S14 | -0.0324165 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0321253 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0321056 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0315719 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0313393 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0311805 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0298481 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0297423 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0291257 |
| RPS13 | ribosomal protein S13 | -0.028892 |
| PCBP2 | poly(rC) binding protein 2 | -0.0288075 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0287629 |
| TENM3 | teneurin transmembrane protein 3 | -0.0287493 |
| GRAMD1B | GRAM domain containing 1B | -0.0283707 |
| RPS15 | ribosomal protein S15 | -0.0280843 |
| GPC6 | glypican 6 | -0.0279026 |
| RPL5 | ribosomal protein L5 | -0.0278456 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0277682 |
| VMP1 | vacuole membrane protein 1 | -0.027751 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0275995 |
| BPTF | bromodomain PHD finger transcription factor | -0.027538 |
| HDAC4 | histone deacetylase 4 | -0.027449 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0274128 |
| ZNF638 | zinc finger protein 638 | -0.0271751 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0271747 |
| RPS16 | ribosomal protein S16 | -0.0267796 |
| EXOC4 | exocyst complex component 4 | -0.026755 |
| RPS8 | ribosomal protein S8 | -0.0266966 |
| PHF20 | PHD finger protein 20 | -0.0263429 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0263082 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0262044 |
| TMSB10 | thymosin beta 10 | -0.0258748 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0258633 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0257895 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0257258 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0256292 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.025572 |
| GPHN | gephyrin | -0.0253751 |
