| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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194 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.219611 |
| FLNB | filamin B, beta | 0.139503 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.134534 |
| NLGN1 | neuroligin 1 | 0.122756 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.117786 |
| RPS6 | ribosomal protein S6 | 0.116782 |
| S100A6 | S100 calcium binding protein A6 | 0.11268 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.10712 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100373 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0997456 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0956227 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0947167 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0923087 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0828211 |
| FTL | ferritin, light polypeptide | 0.0820004 |
| LAMB3 | laminin, beta 3 | 0.0752873 |
| DST | dystonin | 0.0744892 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.073263 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0730617 |
| RPL37A | ribosomal protein L37a | 0.0726758 |
| MED13L | mediator complex subunit 13-like | 0.0705154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0671475 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0591303 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0585709 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0584311 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0584281 |
| RPS3 | ribosomal protein S3 | 0.0547244 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0541721 |
| NRG1 | neuregulin 1 | 0.0534933 |
| TXNRD1 | thioredoxin reductase 1 | 0.0524852 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0520998 |
| TMSB10 | thymosin beta 10 | 0.0495676 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0489998 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0482667 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0455537 |
| ATXN1 | ataxin 1 | 0.0445369 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.044457 |
| HMGA1 | high mobility group AT-hook 1 | 0.0420303 |
| PCBP2 | poly(rC) binding protein 2 | 0.039119 |
| RPS19 | ribosomal protein S19 | 0.0376373 |
| EZR | ezrin | 0.0373698 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0373348 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0373159 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0370417 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0357244 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0355197 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0352741 |
| EGR1 | early growth response 1 | 0.0342829 |
| RPL23 | ribosomal protein L23 | 0.0339764 |
| MATR3 | matrin 3 | 0.0334825 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0333993 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0313714 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0307823 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0305413 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0304839 |
| MYOF | myoferlin | 0.0302888 |
| KLF6 | Kruppel-like factor 6 | 0.0301985 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0283671 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0282136 |
| RPL8 | ribosomal protein L8 | 0.0281565 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0274914 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0273514 |
| EXOC6B | exocyst complex component 6B | 0.0268503 |
| RNF145 | ring finger protein 145 | 0.0256838 |
| MAP4 | microtubule-associated protein 4 | 0.0252627 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0246891 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0225814 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0222003 |
| THOC2 | THO complex 2 | 0.0211926 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0202382 |
| SMYD3 | SET and MYND domain containing 3 | 0.0192297 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.018558 |
| RTN4 | reticulon 4 | 0.0184408 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0177689 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0171651 |
| NDRG1 | N-myc downstream regulated 1 | 0.016972 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0163125 |
| TPM3 | tropomyosin 3 | 0.0144148 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0131908 |
| LMO7 | LIM domain 7 | 0.0128342 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00983409 |
| POMP | proteasome maturation protein | 0.00950702 |
| SPAG9 | sperm associated antigen 9 | 0.00868475 |
| PDE8A | phosphodiesterase 8A | 0.00825805 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0074489 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00669784 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00568628 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.00557398 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.00473318 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00451624 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0045159 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.00449603 |
| RCOR1 | REST corepressor 1 | 0.00351053 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00187479 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0010493 |
| DOCK4 | dedicator of cytokinesis 4 | 4.48968E-4 |
| JARID2 | jumonji, AT rich interactive domain 2 | 3.98224E-4 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 3.11107E-4 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 7.05109E-6 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148703 |
| FN1 | fibronectin 1 | -0.146461 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.129745 |
| EGFR | epidermal growth factor receptor | -0.117031 |
| HDLBP | high density lipoprotein binding protein | -0.107344 |
| B2M | beta-2-microglobulin | -0.106569 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.098279 |
| CALR | calreticulin | -0.0965138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0946495 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0867334 |
| MCL1 | myeloid cell leukemia 1 | -0.0789678 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0762675 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0754128 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.073978 |
| GPATCH2L | G patch domain containing 2-like | -0.0698414 |
| VIM | vimentin | -0.0696821 |
| RBM25 | RNA binding motif protein 25 | -0.0695273 |
| ACTN4 | actinin, alpha 4 | -0.0687177 |
| COG5 | component of oligomeric golgi complex 5 | -0.0626483 |
| VCL | vinculin | -0.0624821 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0617375 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0613421 |
| GOLGA4 | golgin A4 | -0.0611315 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0552201 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0547259 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.052369 |
| MYO1E | myosin IE | -0.0514161 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0510517 |
| MT2A | metallothionein 2A | -0.0492018 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0485409 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0473258 |
| TMEM123 | transmembrane protein 123 | -0.046335 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0429743 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0411448 |
| CD44 | CD44 molecule (Indian blood group) | -0.0411279 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0398429 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0396098 |
| EFNA5 | ephrin-A5 | -0.0378831 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0356236 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0351212 |
| PDE10A | phosphodiesterase 10A | -0.0345996 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0345318 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0340235 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0326106 |
| KYNU | kynureninase | -0.030928 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0306606 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0305688 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0305298 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0302402 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0298402 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0289904 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0286594 |
| MAP7 | microtubule-associated protein 7 | -0.0276972 |
| RPL26 | ribosomal protein L26 | -0.026873 |
| ANXA2 | annexin A2 | -0.025644 |
| HMGA2 | high mobility group AT-hook 2 | -0.0253197 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0249748 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245249 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0233912 |
| NUP58 | nucleoporin 58 | -0.0229012 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0220477 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0203386 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0191605 |
| ZNF292 | zinc finger protein 292 | -0.0187642 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0163818 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0156467 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0141737 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0140704 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0136392 |
| ASPH | aspartate beta-hydroxylase | -0.013611 |
| ENO1 | enolase 1, (alpha) | -0.0136086 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0132656 |
| SON | SON DNA binding protein | -0.0126931 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0114078 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0113547 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0109139 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0101995 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.00941993 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00911461 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.00825486 |
| COL5A2 | collagen, type V, alpha 2 | -0.00811236 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.00718885 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00564133 |
| LAMC2 | laminin, gamma 2 | -0.0056294 |
| AHNAK | AHNAK nucleoprotein | -0.00514002 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00475444 |
| CCNY | cyclin Y | -0.00316522 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.00215274 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.00209996 |
| SF1 | splicing factor 1 | -0.00193739 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00193739 |
| RPL7 | ribosomal protein L7 | -0.00192065 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.00129452 |
| RPL4 | ribosomal protein L4 | -8.38136E-4 |
| RAB10 | RAB10, member RAS oncogene family | -8.01181E-4 |
