| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0538104 |
| SPAG9 | sperm associated antigen 9 | 0.0501737 |
| MKI67 | marker of proliferation Ki-67 | 0.0425528 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0401513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.039382 |
| RHOA | ras homolog family member A | 0.0375002 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0359358 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.03451 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0338444 |
| ANXA1 | annexin A1 | 0.0336192 |
| COL3A1 | collagen, type III, alpha 1 | 0.0333891 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0321939 |
| H1-0 | H1.0 linker histone | 0.0295793 |
| TXNRD1 | thioredoxin reductase 1 | 0.0294015 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0279626 |
| TFRC | transferrin receptor | 0.027381 |
| GOLGA4 | golgin A4 | 0.0268524 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.026381 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0249139 |
| EMP1 | epithelial membrane protein 1 | 0.0238178 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0234697 |
| EZR | ezrin | 0.0233165 |
| RTN4 | reticulon 4 | 0.0226551 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0226386 |
| UBC | ubiquitin C | 0.022446 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0221539 |
| GAP43 | growth associated protein 43 | 0.0220563 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0217553 |
| RPL3 | ribosomal protein L3 | 0.0216095 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0215115 |
| DST | dystonin | 0.0214415 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0212929 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0210761 |
| PCBP2 | poly(rC) binding protein 2 | 0.0210054 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0209847 |
| RPL4 | ribosomal protein L4 | 0.0209789 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0206271 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.02058 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0202965 |
| ANLN | anillin, actin binding protein | 0.0200669 |
| B2M | beta-2-microglobulin | 0.0197266 |
| MB21D2 | Mab-21 domain containing 2 | 0.0195964 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0195942 |
| TMPO | thymopoietin | 0.0190126 |
| RHOH | ras homolog family member H | 0.0189699 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.01885 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0187159 |
| CANX | calnexin | 0.0184824 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0184804 |
| ATP9B | ATPase, class II, type 9B | 0.0183836 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0183773 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0183098 |
| TPTE | transmembrane phosphatase with tensin homology | 0.0180188 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0178259 |
| MORF4L1 | mortality factor 4 like 1 | 0.0177507 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0176901 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0175713 |
| UPP1 | uridine phosphorylase 1 | 0.0175245 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0174132 |
| PTMA | prothymosin, alpha | 0.017365 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0173287 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0171391 |
| POTEF | POTE ankyrin domain family, member F | 0.0170837 |
| ECT2 | epithelial cell transforming 2 | 0.0169295 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0166677 |
| PGK1 | phosphoglycerate kinase 1 | 0.0166334 |
| IGF2 | insulin-like growth factor 2 | 0.0164803 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0164779 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0163912 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.016362 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0162673 |
| TMSB4X | thymosin beta 4, X-linked | 0.0161744 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0161654 |
| NCAPH | non-SMC condensin I complex, subunit H | 0.0160238 |
| TIMELESS | timeless circadian clock | 0.0159617 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0159432 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0159285 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.015883 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.015866 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0158638 |
| USP53 | ubiquitin specific peptidase 53 | 0.0158176 |
| PDS5A | PDS5 cohesin associated factor A | 0.0157679 |
| INSIG2 | insulin induced gene 2 | 0.0157355 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.015675 |
| COLEC11 | collectin sub-family member 11 | 0.015623 |
| SF1 | splicing factor 1 | 0.0155697 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0155689 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0155235 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0153726 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0153612 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0153483 |
| ACTN4 | actinin, alpha 4 | 0.0153316 |
| VCP | valosin containing protein | 0.015064 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0150601 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0149048 |
| SACS | sacsin molecular chaperone | 0.0146569 |
| NBEAL1 | neurobeachin-like 1 | 0.0144486 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0144099 |
| RAI1 | retinoic acid induced 1 | 0.014392 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.0143744 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.169673 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.144105 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.124626 |
| CADM2 | cell adhesion molecule 2 | -0.113162 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.111871 |
| COL11A1 | collagen, type XI, alpha 1 | -0.103903 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0957591 |
| COL5A2 | collagen, type V, alpha 2 | -0.0903201 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0863415 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0832615 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0764514 |
| NTM | neurotrimin | -0.0743576 |
| GPC3 | glypican 3 | -0.0737481 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0685917 |
| MED13L | mediator complex subunit 13-like | -0.0665496 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0627899 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0620788 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0618497 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0618273 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0616759 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0613162 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0611752 |
| PCDH9 | protocadherin 9 | -0.0601936 |
| PARD3B | par-3 family cell polarity regulator beta | -0.057955 |
| MYO10 | myosin X | -0.0564102 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0559301 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0555525 |
| LRRC4C | leucine rich repeat containing 4C | -0.0520214 |
| PHIP | pleckstrin homology domain interacting protein | -0.0499217 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0491941 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0491707 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0489923 |
| SHROOM3 | shroom family member 3 | -0.0467516 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0463629 |
| NHSL1 | NHS-like 1 | -0.0462313 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0451858 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.044258 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0423911 |
| CDH19 | cadherin 19, type 2 | -0.041617 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0415229 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0413069 |
| NEBL | nebulette | -0.0399194 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.039632 |
| PRTG | protogenin | -0.0396281 |
| PRELID2 | PRELI domain containing 2 | -0.0388039 |
| RBM20 | RNA binding motif protein 20 | -0.0386404 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0381879 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0376854 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.037643 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0374222 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0371473 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0360079 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0356528 |
| HMCN1 | hemicentin 1 | -0.0349834 |
| MPG | N-methylpurine-DNA glycosylase | -0.0349696 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0344897 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0344353 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0344281 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0344177 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.03437 |
| RASAL2 | RAS protein activator like 2 | -0.032934 |
| TENM2 | teneurin transmembrane protein 2 | -0.0328212 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0317425 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.031581 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0315606 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0314916 |
| METAP2 | methionyl aminopeptidase 2 | -0.0303634 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0300921 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0298191 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0292809 |
| HDAC9 | histone deacetylase 9 | -0.0290658 |
| WWC2 | WW and C2 domain containing 2 | -0.0288006 |
| GSE1 | Gse1 coiled-coil protein | -0.0285974 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0285464 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0284331 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0282917 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0282479 |
| TENM3 | teneurin transmembrane protein 3 | -0.0278131 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0274786 |
| PRKD1 | protein kinase D1 | -0.0272937 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0269975 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0267586 |
| PLPP1 | phospholipid phosphatase 1 | -0.0266534 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.026207 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0256553 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0256073 |
| UTRN | utrophin | -0.0253024 |
| TOX | thymocyte selection-associated high mobility group box | -0.0252624 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0252139 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0247132 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0245468 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0244868 |
| PDGFC | platelet derived growth factor C | -0.0244215 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0239989 |
| FOXO1 | forkhead box O1 | -0.0234394 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0233355 |
| FOXP2 | forkhead box P2 | -0.0233338 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.02323 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0232145 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0231675 |
