| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0996685 |
| STC1 | stanniocalcin 1 | 0.0886122 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.085902 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0856396 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0854169 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0835539 |
| FLNB | filamin B, beta | 0.0726246 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0692872 |
| RHOA | ras homolog family member A | 0.0639919 |
| MSN | moesin | 0.0636456 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0630129 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0556247 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0522809 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0517698 |
| EZR | ezrin | 0.0509802 |
| PLEC | plectin | 0.0499882 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0493533 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0461289 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0428934 |
| AHNAK | AHNAK nucleoprotein | 0.0421728 |
| GRB10 | growth factor receptor-bound protein 10 | 0.040983 |
| KLF6 | Kruppel-like factor 6 | 0.0403887 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0385859 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0365064 |
| CD109 | CD109 molecule | 0.0361329 |
| FMNL2 | formin-like 2 | 0.0342328 |
| RHOB | ras homolog family member B | 0.0339831 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0338125 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0337409 |
| SPAG9 | sperm associated antigen 9 | 0.0328743 |
| MEF2A | myocyte enhancer factor 2A | 0.0320541 |
| AFDN | afadin, adherens junction formation factor | 0.0315038 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0313688 |
| ATP13A3 | ATPase type 13A3 | 0.0312753 |
| PGK1 | phosphoglycerate kinase 1 | 0.0307678 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.030503 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0293479 |
| NRG1 | neuregulin 1 | 0.028801 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0287178 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0278672 |
| MAP4 | microtubule-associated protein 4 | 0.0275302 |
| NAV2 | neuron navigator 2 | 0.0271666 |
| ABI1 | abl-interactor 1 | 0.0269137 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0268955 |
| MAP1B | microtubule-associated protein 1B | 0.0259114 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.024872 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0244888 |
| TPM3 | tropomyosin 3 | 0.0243123 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0235807 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0234309 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0232462 |
| OXSR1 | oxidative stress responsive 1 | 0.0230294 |
| KLC1 | kinesin light chain 1 | 0.0229115 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0224278 |
| MT2A | metallothionein 2A | 0.0221219 |
| OGA | O-GlcNAcase | 0.0216995 |
| RTN4 | reticulon 4 | 0.0216929 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0209027 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0207129 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0205671 |
| ANXA1 | annexin A1 | 0.0205254 |
| ACTN4 | actinin, alpha 4 | 0.0202184 |
| LMNA | lamin A/C | 0.0195939 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0195896 |
| HMGB2 | high mobility group box 2 | 0.019552 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0193915 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0180423 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0180353 |
| DENND5A | DENN/MADD domain containing 5A | 0.01733 |
| ANLN | anillin, actin binding protein | 0.0172113 |
| SNX9 | sorting nexin 9 | 0.0171834 |
| XPO1 | exportin 1 | 0.0171351 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0168897 |
| SDC4 | syndecan 4 | 0.0167177 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0166422 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0166208 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0165574 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.016459 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0163862 |
| USP3 | ubiquitin specific peptidase 3 | 0.0161137 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0160402 |
| E2F7 | E2F transcription factor 7 | 0.0159925 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0159875 |
| NGLY1 | N-glycanase 1 | 0.0159223 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0158639 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0158535 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.015629 |
| MYO10 | myosin X | 0.0155582 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0155008 |
| DIAPH1 | diaphanous-related formin 1 | 0.0154913 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0154581 |
| NCKAP1 | NCK-associated protein 1 | 0.0154579 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0154519 |
| FBN1 | fibrillin 1 | 0.0154445 |
| RASA2 | RAS p21 protein activator 2 | 0.0154275 |
| FLNA | filamin A, alpha | 0.0154099 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0153393 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0152333 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0152076 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.126743 |
| HLA-B | major histocompatibility complex, class I, B | -0.119814 |
| COL1A2 | collagen, type I, alpha 2 | -0.106862 |
| B2M | beta-2-microglobulin | -0.104141 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0952019 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0832996 |
| ASPH | aspartate beta-hydroxylase | -0.0807117 |
| NRP1 | neuropilin 1 | -0.0798706 |
| CDH13 | cadherin 13 | -0.067818 |
| COL1A1 | collagen, type I, alpha 1 | -0.0627726 |
| FN1 | fibronectin 1 | -0.0610913 |
| TPM1 | tropomyosin 1 (alpha) | -0.0592196 |
| HPCAL1 | hippocalcin-like 1 | -0.0564712 |
| TMEM178B | transmembrane protein 178B | -0.0548014 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0544853 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0544518 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0520867 |
| SP100 | SP100 nuclear antigen | -0.0514226 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0507442 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0498015 |
| EGR1 | early growth response 1 | -0.0496997 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0467 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0461863 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0459789 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0451219 |
| FTL | ferritin, light polypeptide | -0.0446513 |
| GLIS3 | GLIS family zinc finger 3 | -0.0444497 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0441122 |
| FAM20C | family with sequence similarity 20, member C | -0.0440293 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0440074 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0438717 |
| VCL | vinculin | -0.0434481 |
| HLA-A | major histocompatibility complex, class I, A | -0.0430673 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0427572 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0425573 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0422647 |
| POTEF | POTE ankyrin domain family, member F | -0.0404254 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0400493 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0398548 |
| TPM4 | tropomyosin 4 | -0.0394286 |
| HMGA2 | high mobility group AT-hook 2 | -0.0385903 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0375952 |
| IFI44L | interferon-induced protein 44-like | -0.0369673 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0369152 |
| TNNC1 | troponin C type 1 (slow) | -0.0363265 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0355198 |
| HLA-C | major histocompatibility complex, class I, C | -0.0353513 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0351636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0349962 |
| VIM | vimentin | -0.0340798 |
| RIGI | RNA sensor RIG-I | -0.033883 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0338134 |
| PLSCR1 | phospholipid scramblase 1 | -0.0335854 |
| FHIT | fragile histidine triad | -0.0332206 |
| ITGA1 | integrin, alpha 1 | -0.0327015 |
| CD44 | CD44 molecule (Indian blood group) | -0.0326276 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0326147 |
| NAV1 | neuron navigator 1 | -0.032528 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0323392 |
| SHISA5 | shisa family member 5 | -0.0318276 |
| CCDC138 | coiled-coil domain containing 138 | -0.0312382 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0308603 |
| TOP1 | topoisomerase (DNA) I | -0.0307871 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0303012 |
| GOLGA4 | golgin A4 | -0.0299273 |
| COL5A3 | collagen, type V, alpha 3 | -0.029878 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297247 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0292297 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0291053 |
| SMYD3 | SET and MYND domain containing 3 | -0.0287106 |
| HLA-E | major histocompatibility complex, class I, E | -0.0280515 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0280046 |
| SMAD3 | SMAD family member 3 | -0.0279869 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0278225 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0277303 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.027489 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0273804 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0273372 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0272731 |
| ACTG1 | actin gamma 1 | -0.0271475 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0270008 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0268602 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0268195 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0267133 |
| PDE10A | phosphodiesterase 10A | -0.0264278 |
| ITGA11 | integrin, alpha 11 | -0.0262205 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.026212 |
| LOX | lysyl oxidase | -0.026066 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0260016 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0259583 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0258882 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0257255 |
| AFAP1 | actin filament associated protein 1 | -0.025221 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0251461 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0251078 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0250619 |
| LOXL2 | lysyl oxidase-like 2 | -0.0249975 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0248043 |
| KYNU | kynureninase | -0.0241936 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0240115 |
