| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.195591 |
| NLGN1 | neuroligin 1 | 0.145625 |
| LSAMP | limbic system-associated membrane protein | 0.11853 |
| SPAG9 | sperm associated antigen 9 | 0.114947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0945546 |
| HDAC9 | histone deacetylase 9 | 0.0935876 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.093459 |
| CD109 | CD109 molecule | 0.0885049 |
| MAP4 | microtubule-associated protein 4 | 0.0704589 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.068953 |
| ENO1 | enolase 1, (alpha) | 0.0642644 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0625619 |
| ATXN1 | ataxin 1 | 0.0564477 |
| DST | dystonin | 0.0557442 |
| MSN | moesin | 0.0555843 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0518684 |
| EZR | ezrin | 0.0493374 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.049293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0458766 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0456092 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0391046 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0385266 |
| PTMA | prothymosin, alpha | 0.0382226 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.038043 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0370744 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0354164 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0351518 |
| CFAP20DC | CFAP20 domain containing | 0.0345869 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0344328 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0343165 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0342893 |
| PGK1 | phosphoglycerate kinase 1 | 0.0342094 |
| AFF4 | AF4/FMR2 family, member 4 | 0.031943 |
| SFTPA2 | surfactant protein A2 | 0.0315221 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0304084 |
| RHOA | ras homolog family member A | 0.0297805 |
| RHOB | ras homolog family member B | 0.0296581 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0293674 |
| PCBP3 | poly(rC) binding protein 3 | 0.0286441 |
| PLEC | plectin | 0.0285239 |
| CTTN | cortactin | 0.0280129 |
| ABI1 | abl-interactor 1 | 0.0265309 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0264942 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0264828 |
| RAB8B | RAB8B, member RAS oncogene family | 0.026439 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0264002 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0262563 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0255056 |
| LDHA | lactate dehydrogenase A | 0.0249063 |
| MEF2A | myocyte enhancer factor 2A | 0.0248714 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0248348 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0248189 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0246187 |
| S100A10 | S100 calcium binding protein A10 | 0.0237891 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0236948 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0236368 |
| HDAC5 | histone deacetylase 5 | 0.0236133 |
| ANXA5 | annexin A5 | 0.0235248 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0235212 |
| DIAPH1 | diaphanous-related formin 1 | 0.0234778 |
| FNIP2 | folliculin interacting protein 2 | 0.0234232 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0233746 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0230483 |
| AHNAK | AHNAK nucleoprotein | 0.0224402 |
| ANLN | anillin, actin binding protein | 0.0223858 |
| E2F7 | E2F transcription factor 7 | 0.0222343 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0217378 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0216621 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0216066 |
| AFDN | afadin, adherens junction formation factor | 0.0215615 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0210442 |
| DUSP10 | dual specificity phosphatase 10 | 0.0209496 |
| MYO18B | myosin XVIIIB | 0.02085 |
| JUN | jun proto-oncogene | 0.0202621 |
| OTUD7B | OTU deubiquitinase 7B | 0.0202002 |
| RPL3 | ribosomal protein L3 | 0.0200333 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0198183 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0197131 |
| ATF3 | activating transcription factor 3 | 0.0196798 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0196591 |
| LMNA | lamin A/C | 0.0196283 |
| PKM | pyruvate kinase, muscle | 0.0195345 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0194478 |
| ANGPTL4 | angiopoietin-like 4 | 0.0194101 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0193761 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0193242 |
| FAM219A | family with sequence similarity 219, member A | 0.0192562 |
| CENPF | centromere protein F, 350/400kDa | 0.0191183 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0190267 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0189778 |
| B2M | beta-2-microglobulin | 0.0188297 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0187705 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0185393 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0185268 |
| MSI2 | musashi RNA-binding protein 2 | 0.018363 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0182762 |
| ANKRD30B | ankyrin repeat domain 30B | 0.01813 |
| VIM | vimentin | 0.017958 |
| UBC | ubiquitin C | 0.0178925 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0175903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.237102 |
| FMN1 | formin 1 | -0.236702 |
| FN1 | fibronectin 1 | -0.223203 |
| NRG3 | neuregulin 3 | -0.105253 |
| FRMD4A | FERM domain containing 4A | -0.0740883 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0719711 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0716187 |
| FRMD5 | FERM domain containing 5 | -0.0707797 |
| RUNX1 | runt-related transcription factor 1 | -0.0689544 |
| MT2A | metallothionein 2A | -0.0682311 |
| CDK6 | cyclin-dependent kinase 6 | -0.0673408 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0624526 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0599477 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0556836 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0556795 |
| SMAD3 | SMAD family member 3 | -0.0490019 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0477784 |
| FMNL2 | formin-like 2 | -0.0435574 |
| CCND1 | cyclin D1 | -0.0434367 |
| CA8 | carbonic anhydrase VIII | -0.0424892 |
| FHIT | fragile histidine triad | -0.0408233 |
| GOLGA4 | golgin A4 | -0.0405071 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0404337 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0401439 |
| FLNB | filamin B, beta | -0.0387743 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0374322 |
| POTEF | POTE ankyrin domain family, member F | -0.0372621 |
| GPHN | gephyrin | -0.0362631 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0359963 |
| ACTG1 | actin gamma 1 | -0.0353493 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0344197 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0341462 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0340711 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0335086 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.032532 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0324783 |
| RBM25 | RNA binding motif protein 25 | -0.0319064 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0318836 |
| RASAL2 | RAS protein activator like 2 | -0.0313647 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0312109 |
| CDH13 | cadherin 13 | -0.0311928 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0310775 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0309897 |
| MT1X | metallothionein 1X | -0.0304153 |
| FOXP1 | forkhead box P1 | -0.0291734 |
| RPS3 | ribosomal protein S3 | -0.0289287 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0287097 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0285878 |
| PLSCR1 | phospholipid scramblase 1 | -0.028276 |
| CADM1 | cell adhesion molecule 1 | -0.0276768 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0270854 |
| CNKSR3 | CNKSR family member 3 | -0.026971 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0268073 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0264738 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0260478 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0253678 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0249027 |
| TBC1D5 | TBC1 domain family, member 5 | -0.024847 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0246709 |
| PCNX4 | pecanex 4 | -0.0246515 |
| COMMD10 | COMM domain containing 10 | -0.0244098 |
| ERBIN | erbb2 interacting protein | -0.0243852 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0242093 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -0.0239985 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0239196 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0237879 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0237556 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0235502 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.023416 |
| FSTL5 | follistatin-like 5 | -0.0232511 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0230485 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.02303 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0229659 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0227507 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0227087 |
| CALD1 | caldesmon 1 | -0.0226764 |
| DPYD | dihydropyrimidine dehydrogenase | -0.02262 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0225013 |
| NF1 | neurofibromin 1 | -0.0224781 |
| EHBP1 | EH domain binding protein 1 | -0.0223857 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.022286 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0220996 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0218199 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0214452 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0211623 |
| ASPH | aspartate beta-hydroxylase | -0.0210298 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.020789 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | -0.0207886 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.020782 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0207018 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0205597 |
| NKTR | natural killer cell triggering receptor | -0.0203778 |
| ETV6 | ets variant 6 | -0.0202782 |
| PHF14 | PHD finger protein 14 | -0.0199191 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0198804 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0197522 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.019396 |
| PLCB4 | phospholipase C, beta 4 | -0.019363 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0193599 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0193178 |
