| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.197975 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.147793 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.126099 |
| PTMA | prothymosin, alpha | 0.113941 |
| AHNAK | AHNAK nucleoprotein | 0.109007 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.102748 |
| RTN4 | reticulon 4 | 0.0954362 |
| HDAC9 | histone deacetylase 9 | 0.0916716 |
| RHOA | ras homolog family member A | 0.071914 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0686297 |
| ANXA1 | annexin A1 | 0.0647157 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0594561 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0593538 |
| CDC73 | cell division cycle 73 | 0.0581969 |
| TMSB4X | thymosin beta 4, X-linked | 0.0577501 |
| NCKAP1 | NCK-associated protein 1 | 0.0571672 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0564878 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0544815 |
| MEF2A | myocyte enhancer factor 2A | 0.0518356 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0505072 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0502808 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0472042 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0470128 |
| ANK2 | ankyrin 2, neuronal | 0.0469856 |
| FMN1 | formin 1 | 0.0462282 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451802 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0449617 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0448794 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0439265 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0426207 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0421429 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0410279 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0409465 |
| MKI67 | marker of proliferation Ki-67 | 0.04019 |
| PGK1 | phosphoglycerate kinase 1 | 0.0401579 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0399045 |
| ITGA6 | integrin, alpha 6 | 0.03855 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0381368 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037818 |
| CCDC68 | coiled-coil domain containing 68 | 0.0378179 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.037628 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0361685 |
| ZNF292 | zinc finger protein 292 | 0.0360282 |
| GLI2 | GLI family zinc finger 2 | 0.0357228 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.035647 |
| XPO1 | exportin 1 | 0.035429 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0352935 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0351036 |
| ABI1 | abl-interactor 1 | 0.0350028 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0347986 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0346263 |
| SESN2 | sestrin 2 | 0.034356 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0334411 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0333435 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0330298 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0323103 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0315386 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0306313 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0306293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0304389 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0303663 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0302348 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0301209 |
| RHEB | Ras homolog enriched in brain | 0.0299222 |
| PDGFC | platelet derived growth factor C | 0.0298923 |
| PLCE1 | phospholipase C, epsilon 1 | 0.0296648 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0296269 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0295552 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295082 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0293577 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0292904 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.029147 |
| DIAPH3 | diaphanous-related formin 3 | 0.0291061 |
| MSI2 | musashi RNA-binding protein 2 | 0.0290702 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0286658 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0285161 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0283255 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0282068 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0280757 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0277473 |
| H1-4 | H1.4 linker histone, cluster member | 0.0276893 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.0276672 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0275446 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0274611 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0274034 |
| TFG | TRK-fused gene | 0.0273531 |
| HMGB2 | high mobility group box 2 | 0.0266761 |
| APP | amyloid beta (A4) precursor protein | 0.0264124 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0263638 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0258891 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0258522 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0257967 |
| MTMR3 | myotubularin related protein 3 | 0.0250968 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0250181 |
| KLF6 | Kruppel-like factor 6 | 0.0250063 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0250029 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0249396 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0248657 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0248265 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0246932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26248 |
| VCL | vinculin | -0.133435 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.083943 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0806298 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0805799 |
| NBEA | neurobeachin | -0.0770447 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0722093 |
| PKM | pyruvate kinase, muscle | -0.0712282 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0666652 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0620645 |
| POTEF | POTE ankyrin domain family, member F | -0.0601321 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.060008 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0598264 |
| NPAS2 | neuronal PAS domain protein 2 | -0.05934 |
| ACTG1 | actin gamma 1 | -0.0592819 |
| TXNRD1 | thioredoxin reductase 1 | -0.0581298 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0544503 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0541205 |
| GOLGA4 | golgin A4 | -0.0524368 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0478252 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.047515 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0464621 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0458025 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0445759 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0443422 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0443368 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0415375 |
| SMYD3 | SET and MYND domain containing 3 | -0.0403582 |
| PFN1 | profilin 1 | -0.0402668 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0398452 |
| CCND1 | cyclin D1 | -0.0396084 |
| LOXL3 | lysyl oxidase-like 3 | -0.039105 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0389816 |
| PRELID2 | PRELI domain containing 2 | -0.0387767 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0372548 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.036406 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0360108 |
| FLNB | filamin B, beta | -0.035672 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0354459 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.035397 |
| RPS6 | ribosomal protein S6 | -0.0329325 |
| EZR | ezrin | -0.0323843 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0323462 |
| FOXP1 | forkhead box P1 | -0.0319616 |
| RPL35A | ribosomal protein L35a | -0.0316566 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0314513 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0312179 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0309512 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0308029 |
| EGFR | epidermal growth factor receptor | -0.0298438 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0293105 |
| NFIA | nuclear factor I/A | -0.0291767 |
| EVI5 | ecotropic viral integration site 5 | -0.0288873 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0286621 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0285197 |
| KIAA1958 | KIAA1958 | -0.027647 |
| USP34 | ubiquitin specific peptidase 34 | -0.0267332 |
| SBF2 | SET binding factor 2 | -0.0259361 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0258026 |
| LATS2 | large tumor suppressor kinase 2 | -0.025707 |
| TMEM14B | transmembrane protein 14B | -0.0253589 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.025349 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0251173 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0248212 |
| S100A6 | S100 calcium binding protein A6 | -0.0243632 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0242684 |
| AMOTL2 | angiomotin like 2 | -0.0241274 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0239563 |
| DUSP6 | dual specificity phosphatase 6 | -0.023593 |
| GPHN | gephyrin | -0.0233014 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0232103 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.022373 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0221038 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0219675 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0218822 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0218758 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0213167 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0212053 |
| RFX7 | regulatory factor X, 7 | -0.0210987 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0207831 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0205269 |
| DSTN | destrin (actin depolymerizing factor) | -0.0201664 |
| ATRN | attractin | -0.0200622 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0200417 |
| CALU | calumenin | -0.0200129 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0194917 |
| ATM | ATM serine/threonine kinase | -0.0190348 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0188484 |
| AHI1 | Abelson helper integration site 1 | -0.018834 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0181337 |
| ONECUT2 | one cut homeobox 2 | -0.0180766 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0180397 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0180033 |
| TRIM24 | tripartite motif containing 24 | -0.0178971 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0178187 |
| RPL9 | ribosomal protein L9 | -0.0178021 |
| MYO1E | myosin IE | -0.0177471 |
| OSMR | oncostatin M receptor | -0.0176473 |
| ARF4 | ADP-ribosylation factor 4 | -0.0176326 |
| ZNF638 | zinc finger protein 638 | -0.0174887 |
