| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.240351 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.221284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.117482 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0787779 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0740977 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0731879 |
| NAV2 | neuron navigator 2 | 0.068957 |
| MSN | moesin | 0.0672731 |
| SPAG9 | sperm associated antigen 9 | 0.0672179 |
| FMNL2 | formin-like 2 | 0.0660023 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0654166 |
| RPS12 | ribosomal protein S12 | 0.0646829 |
| PTMA | prothymosin, alpha | 0.0618729 |
| MT2A | metallothionein 2A | 0.0581963 |
| TMSB10 | thymosin beta 10 | 0.0548705 |
| EZR | ezrin | 0.0543257 |
| KLF6 | Kruppel-like factor 6 | 0.0543107 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.05378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0528852 |
| FTL | ferritin, light polypeptide | 0.0496325 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0488722 |
| RPS3 | ribosomal protein S3 | 0.0485003 |
| ATP13A3 | ATPase type 13A3 | 0.0482708 |
| ENO1 | enolase 1, (alpha) | 0.0480734 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0462843 |
| CADM1 | cell adhesion molecule 1 | 0.0460722 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0431565 |
| RPS6 | ribosomal protein S6 | 0.0430086 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0428506 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0424714 |
| RPS8 | ribosomal protein S8 | 0.0407895 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0407242 |
| PLIN2 | perilipin 2 | 0.0404848 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0401807 |
| TPM3 | tropomyosin 3 | 0.039979 |
| RAI1 | retinoic acid induced 1 | 0.0398527 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0393262 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0390301 |
| DENND5A | DENN/MADD domain containing 5A | 0.0389347 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.037581 |
| RTN4 | reticulon 4 | 0.0375467 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0371549 |
| RPL23 | ribosomal protein L23 | 0.0361537 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0361412 |
| RPL37A | ribosomal protein L37a | 0.0357784 |
| DST | dystonin | 0.0355372 |
| RPL26 | ribosomal protein L26 | 0.0347181 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0332913 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0331141 |
| MAP1B | microtubule-associated protein 1B | 0.032893 |
| SEPTIN9 | septin 9 | 0.0322939 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0316709 |
| APP | amyloid beta (A4) precursor protein | 0.0315171 |
| HDAC9 | histone deacetylase 9 | 0.0311936 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0303017 |
| PCBP2 | poly(rC) binding protein 2 | 0.0298292 |
| DSTN | destrin (actin depolymerizing factor) | 0.0296947 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0296298 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0294747 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0293844 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0293508 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0286373 |
| MYLK | myosin light chain kinase | 0.0284243 |
| RPS17 | ribosomal protein S17 | 0.0282404 |
| CD109 | CD109 molecule | 0.0280266 |
| OPTN | optineurin | 0.0279467 |
| TMSB4X | thymosin beta 4, X-linked | 0.0276417 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.02755 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0275294 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0274903 |
| ANXA1 | annexin A1 | 0.0274404 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0273956 |
| PTK2 | protein tyrosine kinase 2 | 0.0268792 |
| TPI1 | triosephosphate isomerase 1 | 0.0265333 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0265025 |
| ANXA5 | annexin A5 | 0.0262761 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0255161 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0253156 |
| USP12 | ubiquitin specific peptidase 12 | 0.0252145 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0249496 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0249398 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244988 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0244016 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.024152 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0239821 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0239484 |
| CD44 | CD44 molecule (Indian blood group) | 0.0234601 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0233184 |
| CLIC4 | chloride intracellular channel 4 | 0.0233133 |
| RPL3 | ribosomal protein L3 | 0.0232136 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0229026 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0227462 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0227367 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0227112 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0225628 |
| FNIP2 | folliculin interacting protein 2 | 0.0224905 |
| ABI1 | abl-interactor 1 | 0.0223049 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0221196 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0220358 |
| SBF2 | SET binding factor 2 | 0.022029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GLIS3 | GLIS family zinc finger 3 | -0.149652 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148583 |
| VCL | vinculin | -0.117041 |
| BICC1 | BicC family RNA binding protein 1 | -0.10647 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.102246 |
| FRMD4A | FERM domain containing 4A | -0.0977752 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0692466 |
| SMAD3 | SMAD family member 3 | -0.0646629 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0608602 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0588627 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0558039 |
| PDE10A | phosphodiesterase 10A | -0.0552696 |
| SMYD3 | SET and MYND domain containing 3 | -0.0547418 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0545363 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0517127 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0511031 |
| THBS1 | thrombospondin 1 | -0.0492978 |
| HLA-B | major histocompatibility complex, class I, B | -0.0476659 |
| KYNU | kynureninase | -0.0475227 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0473802 |
| RIGI | RNA sensor RIG-I | -0.0442207 |
| VMP1 | vacuole membrane protein 1 | -0.042178 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0412299 |
| CDH13 | cadherin 13 | -0.0404695 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0387203 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0382354 |
| HMGA2 | high mobility group AT-hook 2 | -0.0375169 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0363215 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.035216 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0348968 |
| DPYD | dihydropyrimidine dehydrogenase | -0.034783 |
| GPC6 | glypican 6 | -0.0339889 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0339264 |
| EHBP1 | EH domain binding protein 1 | -0.0337867 |
| RNF213 | ring finger protein 213 | -0.0332892 |
| MKI67 | marker of proliferation Ki-67 | -0.032057 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0317198 |
| CANX | calnexin | -0.0316861 |
| THOC2 | THO complex 2 | -0.031279 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0312699 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0307867 |
| VCAN | versican | -0.0306378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0305502 |
| LOX | lysyl oxidase | -0.0304224 |
| TPM1 | tropomyosin 1 (alpha) | -0.0303866 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0302748 |
| NRP1 | neuropilin 1 | -0.0301492 |
| SP100 | SP100 nuclear antigen | -0.0290678 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0287865 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0286091 |
| GOLGB1 | golgin B1 | -0.0284129 |
| MORF4L2 | mortality factor 4 like 2 | -0.0283952 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0283782 |
| NABP1 | nucleic acid binding protein 1 | -0.0282433 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.028228 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.027398 |
| METTL15 | methyltransferase like 15 | -0.0268732 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0264194 |
| PHF21A | PHD finger protein 21A | -0.0263367 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0261735 |
| INTS6 | integrator complex subunit 6 | -0.026011 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0259831 |
| PGK1 | phosphoglycerate kinase 1 | -0.0259648 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0259383 |
| TENM2 | teneurin transmembrane protein 2 | -0.0259069 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0258313 |
| NCKAP5 | NCK-associated protein 5 | -0.025783 |
| NF1 | neurofibromin 1 | -0.0254659 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.025286 |
| LRRC7 | leucine rich repeat containing 7 | -0.0252101 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0252017 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0249748 |
| LDHA | lactate dehydrogenase A | -0.0249664 |
| BPTF | bromodomain PHD finger transcription factor | -0.0248423 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0247423 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0235364 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.023461 |
| RBM39 | RNA binding motif protein 39 | -0.0234007 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0233062 |
| HDAC8 | histone deacetylase 8 | -0.0232356 |
| PLSCR1 | phospholipid scramblase 1 | -0.0230948 |
| PALLD | palladin, cytoskeletal associated protein | -0.0229703 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0229306 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0229262 |
| FAM20C | family with sequence similarity 20, member C | -0.0228679 |
| MYO10 | myosin X | -0.0228544 |
| PMP22 | peripheral myelin protein 22 | -0.0227403 |
| OSMR | oncostatin M receptor | -0.0226111 |
| RAI14 | retinoic acid induced 14 | -0.0224505 |
| PHF3 | PHD finger protein 3 | -0.022271 |
| ANXA2 | annexin A2 | -0.0222242 |
| HLA-E | major histocompatibility complex, class I, E | -0.0221359 |
| TRIM55 | tripartite motif containing 55 | -0.0220459 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0219317 |
| FOXP1 | forkhead box P1 | -0.0218187 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0217824 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0217422 |
| ATM | ATM serine/threonine kinase | -0.0217351 |
| FN1 | fibronectin 1 | -0.0216353 |
| JAK2 | Janus kinase 2 | -0.0214052 |
