| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0740968 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0486526 |
| PTMA | prothymosin, alpha | 0.0475241 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0438099 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0420345 |
| RIOK3 | RIO kinase 3 | 0.0398454 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0384424 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.036933 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0355476 |
| AFDN | afadin, adherens junction formation factor | 0.0353532 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0349296 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0343482 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0341363 |
| SPAG9 | sperm associated antigen 9 | 0.0335049 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0308491 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.030549 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0287102 |
| KLF10 | Kruppel-like factor 10 | 0.0286714 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.027646 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0266974 |
| C3 | complement component 3 | 0.0263767 |
| EZR | ezrin | 0.0254072 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0249986 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0248735 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0246731 |
| PARD3 | par-3 family cell polarity regulator | 0.0246359 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0245734 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0243591 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.024068 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0238587 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0235 |
| SEPTIN9 | septin 9 | 0.0234446 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0231326 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0230224 |
| SMAD3 | SMAD family member 3 | 0.0229089 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0227241 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0226247 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0224741 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0223609 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0218232 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0214973 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0213371 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0212717 |
| CSTB | cystatin B (stefin B) | 0.0206784 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0205939 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0203944 |
| ACTN4 | actinin, alpha 4 | 0.0199344 |
| AOPEP | aminopeptidase O (putative) | 0.0196457 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0196167 |
| SELENOF | selenoprotein F | 0.0195604 |
| CTBP2 | C-terminal binding protein 2 | 0.0195 |
| RBM39 | RNA binding motif protein 39 | 0.0194717 |
| MSI2 | musashi RNA-binding protein 2 | 0.0192818 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0191732 |
| CD47 | CD47 molecule | 0.0191506 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0189443 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0189403 |
| IRF1 | interferon regulatory factor 1 | 0.0188631 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0187995 |
| KLF6 | Kruppel-like factor 6 | 0.0187536 |
| RHOB | ras homolog family member B | 0.0186861 |
| NUP58 | nucleoporin 58 | 0.0186573 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0185168 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0184687 |
| FNBP1L | formin binding protein 1-like | 0.0184403 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0180447 |
| SERINC1 | serine incorporator 1 | 0.0178969 |
| FNBP1 | formin binding protein 1 | 0.0178555 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0177383 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0177346 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0176518 |
| USP3 | ubiquitin specific peptidase 3 | 0.0175065 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0174899 |
| DENND4A | DENN/MADD domain containing 4A | 0.017439 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0173388 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0172789 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0172101 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.017187 |
| TXNIP | thioredoxin interacting protein | 0.0171704 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0171018 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0169323 |
| CTNNBL1 | catenin, beta like 1 | 0.016893 |
| RLF | rearranged L-myc fusion | 0.01683 |
| PLEC | plectin | 0.0167943 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0167138 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0164956 |
| DIAPH2 | diaphanous-related formin 2 | 0.016457 |
| IGF2 | insulin-like growth factor 2 | 0.0163729 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0161956 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0161206 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0161071 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0159976 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0159913 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0159728 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.0159031 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.01589 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0158519 |
| WDR33 | WD repeat domain 33 | 0.0157295 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0157065 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0156872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.392033 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.262585 |
| COL6A3 | collagen, type VI, alpha 3 | -0.20386 |
| HLA-B | major histocompatibility complex, class I, B | -0.110597 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0988595 |
| VIM | vimentin | -0.0969976 |
| FN1 | fibronectin 1 | -0.0967401 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.096623 |
| B2M | beta-2-microglobulin | -0.0855989 |
| POTEF | POTE ankyrin domain family, member F | -0.0809749 |
| LOX | lysyl oxidase | -0.0807294 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0799868 |
| MT2A | metallothionein 2A | -0.0753006 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0752095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736706 |
| VCL | vinculin | -0.0734414 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0733028 |
| NRXN3 | neurexin 3 | -0.0701637 |
| CALD1 | caldesmon 1 | -0.0674391 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0666721 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0637673 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0632909 |
| CDH13 | cadherin 13 | -0.0613861 |
| GLIS3 | GLIS family zinc finger 3 | -0.0612088 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0572245 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0569971 |
| EGFR | epidermal growth factor receptor | -0.0569212 |
| STC1 | stanniocalcin 1 | -0.0566443 |
| HMGA2 | high mobility group AT-hook 2 | -0.0566408 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0559251 |
| PRSS23 | protease, serine, 23 | -0.0556415 |
| CALU | calumenin | -0.0554305 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0551267 |
| COL5A1 | collagen, type V, alpha 1 | -0.0541628 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0523391 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0507773 |
| TNS3 | tensin 3 | -0.0505476 |
| CANX | calnexin | -0.0468477 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.044627 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0445864 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.043931 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0438836 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0427496 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0423673 |
| LOXL2 | lysyl oxidase-like 2 | -0.0420415 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0419732 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0416197 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0412034 |
| CDK6 | cyclin-dependent kinase 6 | -0.0404527 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0403255 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.040082 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0398767 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0386778 |
| TPM1 | tropomyosin 1 (alpha) | -0.0385135 |
| MAP1B | microtubule-associated protein 1B | -0.0382355 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0381972 |
| ENO1 | enolase 1, (alpha) | -0.0381691 |
| HLA-A | major histocompatibility complex, class I, A | -0.0374848 |
| RAI14 | retinoic acid induced 14 | -0.0364104 |
| SMYD3 | SET and MYND domain containing 3 | -0.0361892 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0356776 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0341 |
| IL6 | interleukin 6 | -0.0328214 |
| CD44 | CD44 molecule (Indian blood group) | -0.0327731 |
| VEGFC | vascular endothelial growth factor C | -0.0324065 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0322584 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0320545 |
| ASPH | aspartate beta-hydroxylase | -0.0316281 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0312741 |
| KAZN | kazrin, periplakin interacting protein | -0.031247 |
| MMP12 | matrix metallopeptidase 12 | -0.0311537 |
| ECE1 | endothelin converting enzyme 1 | -0.0310659 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0309055 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0304401 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0304226 |
| RND3 | Rho family GTPase 3 | -0.0301994 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0298765 |
| HDLBP | high density lipoprotein binding protein | -0.0296512 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0293099 |
| FNIP1 | folliculin interacting protein 1 | -0.029229 |
| HLA-C | major histocompatibility complex, class I, C | -0.0290025 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290013 |
| EXOC4 | exocyst complex component 4 | -0.0288218 |
| RNF24 | ring finger protein 24 | -0.0287469 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0287168 |
| KYNU | kynureninase | -0.028383 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0282655 |
| RNF145 | ring finger protein 145 | -0.0282567 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.027977 |
| CALR | calreticulin | -0.0278053 |
| ACTN1 | actinin, alpha 1 | -0.0277943 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0277674 |
| TMSB10 | thymosin beta 10 | -0.0277031 |
| DSTN | destrin (actin depolymerizing factor) | -0.0274084 |
| NRP1 | neuropilin 1 | -0.0272845 |
| NDRG1 | N-myc downstream regulated 1 | -0.027239 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0272291 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0272047 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0269636 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0267468 |
