| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0724542 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0681597 |
| CENPF | centromere protein F, 350/400kDa | 0.0570087 |
| TPX2 | TPX2, microtubule-associated | 0.0521061 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0516921 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0509139 |
| DIAPH3 | diaphanous-related formin 3 | 0.048159 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0468931 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0454724 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0431896 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0431776 |
| ANXA1 | annexin A1 | 0.0423768 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0413924 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0408417 |
| CEP250 | centrosomal protein 250kDa | 0.0388376 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0363223 |
| ANLN | anillin, actin binding protein | 0.0361544 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0361096 |
| SGO2 | shugoshin 2 | 0.0356956 |
| TXNRD1 | thioredoxin reductase 1 | 0.0356535 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0356514 |
| SPAG9 | sperm associated antigen 9 | 0.0353595 |
| MKI67 | marker of proliferation Ki-67 | 0.0352593 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0336884 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0332807 |
| CANX | calnexin | 0.0327256 |
| HMGB2 | high mobility group box 2 | 0.0326276 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0313392 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0308536 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0305919 |
| SET | SET nuclear proto-oncogene | 0.0305483 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0303333 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0291111 |
| GOLGA4 | golgin A4 | 0.0289442 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0283523 |
| RPL23 | ribosomal protein L23 | 0.0283235 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0281294 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0280546 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0278695 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0272911 |
| XPO1 | exportin 1 | 0.027209 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0269266 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0260953 |
| PRPF4B | pre-mRNA processing factor 4B | 0.02586 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0256585 |
| KIF5B | kinesin family member 5B | 0.0255846 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253124 |
| PHIP | pleckstrin homology domain interacting protein | 0.0252256 |
| KIAA1958 | KIAA1958 | 0.0250719 |
| RBM39 | RNA binding motif protein 39 | 0.0247956 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0246716 |
| KIF4A | kinesin family member 4A | 0.0245082 |
| NUP58 | nucleoporin 58 | 0.024472 |
| RRBP1 | ribosome binding protein 1 | 0.0242972 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0238873 |
| CEP295 | centrosomal protein 295kDa | 0.0236773 |
| CEP192 | centrosomal protein 192kDa | 0.0236444 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0235132 |
| HSPA8 | heat shock 70kDa protein 8 | 0.022857 |
| CEP95 | centrosomal protein 95kDa | 0.0227434 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.02261 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0225341 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0221832 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0221662 |
| UBQLN1 | ubiquilin 1 | 0.022151 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0219686 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0215626 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0214237 |
| CEP70 | centrosomal protein 70kDa | 0.0212571 |
| FANCI | Fanconi anemia, complementation group I | 0.0211036 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0210228 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0209861 |
| KIF20B | kinesin family member 20B | 0.0209504 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0209452 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0207712 |
| HJURP | Holliday junction recognition protein | 0.0205867 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0202641 |
| KIAA1328 | KIAA1328 | 0.0202197 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0201664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0201513 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0200282 |
| PCBP2 | poly(rC) binding protein 2 | 0.0198993 |
| KIF23 | kinesin family member 23 | 0.0198148 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0197789 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0196346 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0195767 |
| CEP128 | centrosomal protein 128kDa | 0.0194647 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0192974 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0190817 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0189842 |
| PARPBP | PARP1 binding protein | 0.018969 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0189314 |
| EZR | ezrin | 0.018865 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0186876 |
| TUBB4B | tubulin, beta 4B class IVb | 0.01868 |
| NRBP1 | nuclear receptor binding protein 1 | 0.0185759 |
| FAM13A | family with sequence similarity 13, member A | 0.0185692 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0184247 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0183195 |
| CALU | calumenin | 0.018285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260541 |
| FNDC3B | fibronectin type III domain containing 3B | -0.147173 |
| POTEF | POTE ankyrin domain family, member F | -0.085183 |
| PRKCA | protein kinase C, alpha | -0.0801067 |
| HMGA2 | high mobility group AT-hook 2 | -0.0798777 |
| TMSB10 | thymosin beta 10 | -0.0744403 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.069262 |
| FMNL2 | formin-like 2 | -0.068228 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0674763 |
| MT2A | metallothionein 2A | -0.0672199 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0636459 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0634131 |
| ANGPTL4 | angiopoietin-like 4 | -0.0623438 |
| PRR16 | proline rich 16 | -0.056358 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0547198 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0532523 |
| VIM | vimentin | -0.0526309 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0514228 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0504803 |
| CD44 | CD44 molecule (Indian blood group) | -0.0502242 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0500898 |
| PRSS23 | protease, serine, 23 | -0.0500254 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0499868 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0497894 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0489838 |
| RAI14 | retinoic acid induced 14 | -0.0487958 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0486611 |
| B2M | beta-2-microglobulin | -0.0456039 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0443656 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0443459 |
| DST | dystonin | -0.0435759 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0432277 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0428345 |
| NALCN | sodium leak channel, non selective | -0.0426188 |
| PARD3 | par-3 family cell polarity regulator | -0.0423325 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0410991 |
| EGR1 | early growth response 1 | -0.0406986 |
| HLA-B | major histocompatibility complex, class I, B | -0.0403538 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0402726 |
| PODXL | podocalyxin-like | -0.0394043 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0393113 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0389572 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0385566 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0383737 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0365947 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0364581 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0361863 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0360092 |
| VCL | vinculin | -0.0347833 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0347111 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0342857 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0340149 |
| RAD51B | RAD51 paralog B | -0.0335941 |
| SVIL | supervillin | -0.0333209 |
| ACTG1 | actin gamma 1 | -0.0328826 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0327493 |
| ATM | ATM serine/threonine kinase | -0.0318127 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0315633 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0313194 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0311257 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.03105 |
| OSMR | oncostatin M receptor | -0.0308234 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0306264 |
| FLNB | filamin B, beta | -0.0305402 |
| PCED1B | PC-esterase domain containing 1B | -0.0302622 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0302047 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0299492 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0299207 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0298223 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0294083 |
| ZFHX3 | zinc finger homeobox 3 | -0.0292922 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0291916 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0291258 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0288923 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0285204 |
| RIN2 | Ras and Rab interactor 2 | -0.0284472 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0282815 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0282003 |
| AEBP2 | AE binding protein 2 | -0.0278983 |
| LDHA | lactate dehydrogenase A | -0.0278472 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0275293 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0274619 |
| FBXO11 | F-box protein 11 | -0.0274173 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0274173 |
| MCL1 | myeloid cell leukemia 1 | -0.027413 |
| CDCP1 | CUB domain containing protein 1 | -0.0273905 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.0273527 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0272445 |
| LAMA5 | laminin, alpha 5 | -0.0272327 |
| RORA | RAR-related orphan receptor A | -0.0270132 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0269973 |
| S100A10 | S100 calcium binding protein A10 | -0.0269132 |
| IGF2 | insulin-like growth factor 2 | -0.0268981 |
| IER3 | immediate early response 3 | -0.0263076 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0261984 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0259112 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0258979 |
| PTK2 | protein tyrosine kinase 2 | -0.0258224 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0257757 |
| PFN1 | profilin 1 | -0.0257722 |
