| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD109 | CD109 molecule | 0.10688 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.059774 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0552879 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0539343 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0478742 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0464317 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.04433 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0402506 |
| DST | dystonin | 0.0377881 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0377635 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.037684 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0353193 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0351685 |
| TXNRD1 | thioredoxin reductase 1 | 0.0335067 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0330547 |
| RNF145 | ring finger protein 145 | 0.0328661 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0315254 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0304848 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0301648 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0298449 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0296726 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0292086 |
| ARRDC3 | arrestin domain containing 3 | 0.0291156 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0282347 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0271407 |
| JAK1 | Janus kinase 1 | 0.0271 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0266263 |
| USP12 | ubiquitin specific peptidase 12 | 0.026423 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0263795 |
| RPS6 | ribosomal protein S6 | 0.0250689 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.024693 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0239586 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0235093 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0229301 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0228337 |
| FMN1 | formin 1 | 0.0228154 |
| RPS12 | ribosomal protein S12 | 0.0223747 |
| DIAPH3 | diaphanous-related formin 3 | 0.0222876 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0218554 |
| AHR | aryl hydrocarbon receptor | 0.0215052 |
| HDGF | hepatoma-derived growth factor | 0.0211785 |
| XPO1 | exportin 1 | 0.0204529 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0200455 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0194181 |
| WDR43 | WD repeat domain 43 | 0.0192132 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0191897 |
| EZR | ezrin | 0.0191707 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0188898 |
| RPL13A | ribosomal protein L13a | 0.0186491 |
| RPS19 | ribosomal protein S19 | 0.0186043 |
| RPL3 | ribosomal protein L3 | 0.0182053 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0177089 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0175746 |
| RAB18 | RAB18, member RAS oncogene family | 0.017468 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0174451 |
| HELZ | helicase with zinc finger | 0.0174067 |
| RHOB | ras homolog family member B | 0.0173354 |
| ATL2 | atlastin GTPase 2 | 0.0173244 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0172597 |
| RTN4 | reticulon 4 | 0.0171219 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0171217 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0169341 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0168341 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0168217 |
| CD44 | CD44 molecule (Indian blood group) | 0.0167841 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0167572 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0167488 |
| NEK7 | NIMA-related kinase 7 | 0.0167482 |
| UBTD2 | ubiquitin domain containing 2 | 0.0166969 |
| SNX13 | sorting nexin 13 | 0.0166229 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0162011 |
| SPAG9 | sperm associated antigen 9 | 0.0161928 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.016136 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0160652 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0159081 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0158711 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0156032 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0155975 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0155748 |
| INSIG1 | insulin induced gene 1 | 0.0154795 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0153394 |
| FAM13A | family with sequence similarity 13, member A | 0.0153202 |
| USP3 | ubiquitin specific peptidase 3 | 0.0151751 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0151581 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0151414 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | 0.0149183 |
| FOSL2 | FOS-like antigen 2 | 0.0148589 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0148366 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0146898 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0146487 |
| VRK2 | vaccinia related kinase 2 | 0.0145242 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0145167 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0144915 |
| RPL12 | ribosomal protein L12 | 0.0144122 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0143575 |
| ABI1 | abl-interactor 1 | 0.0143355 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0141577 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.014151 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0140986 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0140276 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.298952 |
| NRG1 | neuregulin 1 | -0.279095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.253859 |
| HMGA2 | high mobility group AT-hook 2 | -0.230046 |
| ITGA1 | integrin, alpha 1 | -0.191328 |
| ASPH | aspartate beta-hydroxylase | -0.159667 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.13049 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.12259 |
| GLIS3 | GLIS family zinc finger 3 | -0.116612 |
| EFNA5 | ephrin-A5 | -0.106051 |
| TMEM156 | transmembrane protein 156 | -0.102373 |
| SQSTM1 | sequestosome 1 | -0.085155 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0734422 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0734361 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.072856 |
| VCL | vinculin | -0.072635 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0718316 |
| NRP1 | neuropilin 1 | -0.0680117 |
| CANX | calnexin | -0.0619832 |
| HLA-B | major histocompatibility complex, class I, B | -0.0600786 |
| SYT1 | synaptotagmin I | -0.0598223 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.059718 |
| OSMR | oncostatin M receptor | -0.0565398 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0564805 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0548601 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0525978 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0522391 |
| ETV1 | ets variant 1 | -0.0515078 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0488005 |
| UBC | ubiquitin C | -0.0466569 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0463555 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0455135 |
| RAI14 | retinoic acid induced 14 | -0.0443141 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.044247 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0440807 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0424785 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0419518 |
| STC2 | stanniocalcin 2 | -0.0410065 |
| HPCAL1 | hippocalcin-like 1 | -0.0397 |
| KLHL5 | kelch-like family member 5 | -0.0396014 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0394905 |
| ACTG1 | actin gamma 1 | -0.0392991 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0385768 |
| AEBP2 | AE binding protein 2 | -0.0381914 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0376494 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0367795 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0365845 |
| TMSB4X | thymosin beta 4, X-linked | -0.0364855 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0362079 |
| DUSP6 | dual specificity phosphatase 6 | -0.0361334 |
| SMYD3 | SET and MYND domain containing 3 | -0.0358025 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0353738 |
| CALU | calumenin | -0.035341 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0347342 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0346818 |
| TSC22D1 | TSC22 domain family, member 1 | -0.03454 |
| TOP1 | topoisomerase (DNA) I | -0.0342638 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0341477 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.033742 |
| CDCP1 | CUB domain containing protein 1 | -0.0332645 |
| ENO1 | enolase 1, (alpha) | -0.0320793 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0317929 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0316701 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0311937 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0309668 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0299298 |
| FAM20C | family with sequence similarity 20, member C | -0.0293014 |
| PTMA | prothymosin, alpha | -0.0292225 |
| VEGFC | vascular endothelial growth factor C | -0.0289973 |
| PELO | pelota homolog (Drosophila) | -0.0283583 |
| POTEF | POTE ankyrin domain family, member F | -0.0282907 |
| TMSB10 | thymosin beta 10 | -0.0277265 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0276517 |
| LOXL2 | lysyl oxidase-like 2 | -0.0276415 |
| NAV1 | neuron navigator 1 | -0.0274957 |
| TGFA | transforming growth factor, alpha | -0.0273269 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.02686 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0267836 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0266621 |
| SEPTIN9 | septin 9 | -0.0266139 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0264523 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0263793 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0262723 |
| SFTPA2 | surfactant protein A2 | -0.0259692 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0257281 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0255552 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0254097 |
| S100A6 | S100 calcium binding protein A6 | -0.0251356 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0250519 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024984 |
| RAD51B | RAD51 paralog B | -0.0247446 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0246997 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0243653 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0242361 |
| NDRG1 | N-myc downstream regulated 1 | -0.0241118 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0240854 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0240738 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0239928 |
| SMAD3 | SMAD family member 3 | -0.0239717 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0239197 |
