| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0825477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0425281 |
| ABHD2 | abhydrolase domain containing 2 | 0.0392039 |
| INTS6 | integrator complex subunit 6 | 0.0348557 |
| KLF6 | Kruppel-like factor 6 | 0.0305732 |
| RPL3 | ribosomal protein L3 | 0.0292641 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0275243 |
| DSPP | dentin sialophosphoprotein | 0.0253249 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0241874 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0215454 |
| ATXN1 | ataxin 1 | 0.0202367 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0196398 |
| DIAPH3 | diaphanous-related formin 3 | 0.0194026 |
| AHNAK | AHNAK nucleoprotein | 0.0193747 |
| NEBL | nebulette | 0.018854 |
| MAP1B | microtubule-associated protein 1B | 0.0188249 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0180529 |
| KIF16B | kinesin family member 16B | 0.0177035 |
| SPAG9 | sperm associated antigen 9 | 0.0175297 |
| MAP4 | microtubule-associated protein 4 | 0.0172197 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0171137 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0166761 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0160755 |
| AFDN | afadin, adherens junction formation factor | 0.0158581 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0158575 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0156861 |
| RBM33 | RNA binding motif protein 33 | 0.0155353 |
| PLEC | plectin | 0.0154556 |
| KLC1 | kinesin light chain 1 | 0.0153061 |
| FOXO3 | forkhead box O3 | 0.0151201 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0150447 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0147508 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0145743 |
| MSN | moesin | 0.0142447 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0141951 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0141471 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.013557 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0131597 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0130657 |
| RHOB | ras homolog family member B | 0.0130089 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0129107 |
| OGA | O-GlcNAcase | 0.0128098 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0127692 |
| RPSA | ribosomal protein SA | 0.0125609 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0125116 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0123892 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0121273 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.012073 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0120291 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0120248 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0118373 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0117878 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0116015 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0115914 |
| HMGB2 | high mobility group box 2 | 0.0115666 |
| H1-4 | H1.4 linker histone, cluster member | 0.0114498 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0113184 |
| H1-2 | H1.2 linker histone, cluster member | 0.0112036 |
| ANO10 | anoctamin 10 | 0.0110232 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0110069 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0110023 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0109444 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0109026 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0108893 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0107184 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0106288 |
| DENND5A | DENN/MADD domain containing 5A | 0.0106272 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0105666 |
| UBAP1 | ubiquitin associated protein 1 | 0.0105199 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0104983 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0103511 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0102535 |
| NCKAP1 | NCK-associated protein 1 | 0.010227 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0102202 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0101506 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0101499 |
| CNTNAP2 | contactin associated protein-like 2 | 0.0101454 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0101437 |
| RHOA | ras homolog family member A | 0.0101437 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.010126 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0101051 |
| CYTH1 | cytohesin 1 | 0.00980217 |
| PCBP3 | poly(rC) binding protein 3 | 0.00972302 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00965667 |
| MYO5B | myosin VB | 0.00963835 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00955308 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0094438 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00941615 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.00936844 |
| CPNE1 | copine I | 0.00931493 |
| CEP128 | centrosomal protein 128kDa | 0.00924917 |
| COPA | coatomer protein complex, subunit alpha | 0.00914716 |
| NUP58 | nucleoporin 58 | 0.00911182 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.00905641 |
| RPS18 | ribosomal protein S18 | 0.00900918 |
| SERINC1 | serine incorporator 1 | 0.00900159 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00899287 |
| BSDC1 | BSD domain containing 1 | 0.00896874 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.00896199 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.00895517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18595 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.181647 |
| RPS6 | ribosomal protein S6 | -0.111319 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.104647 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.103627 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.100206 |
| RPL35A | ribosomal protein L35a | -0.0989616 |
| PTMA | prothymosin, alpha | -0.0954023 |
| ACTG1 | actin gamma 1 | -0.0937338 |
| CCND1 | cyclin D1 | -0.0894436 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0823489 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0817926 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0795967 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.070099 |
| ACTN4 | actinin, alpha 4 | -0.065919 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0653822 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0649424 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0641015 |
| CDK6 | cyclin-dependent kinase 6 | -0.0630767 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0626624 |
| TMSB10 | thymosin beta 10 | -0.0623983 |
| EGR1 | early growth response 1 | -0.0588097 |
| RPS8 | ribosomal protein S8 | -0.0583421 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0577056 |
| LDHA | lactate dehydrogenase A | -0.0569455 |
| VIM | vimentin | -0.0559915 |
| ANXA2 | annexin A2 | -0.0559376 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.05527 |
| TMEM123 | transmembrane protein 123 | -0.0549087 |
| RPS13 | ribosomal protein S13 | -0.0545691 |
| NAV2 | neuron navigator 2 | -0.0542106 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0512856 |
| POTEF | POTE ankyrin domain family, member F | -0.0508498 |
| TPM4 | tropomyosin 4 | -0.050599 |
| MT2A | metallothionein 2A | -0.0496092 |
| HMGA1 | high mobility group AT-hook 1 | -0.049125 |
| KRT18 | keratin 18, type I | -0.0476623 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0471069 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0460904 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0456554 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455305 |
| THOC2 | THO complex 2 | -0.0450469 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.04381 |
| RPS24 | ribosomal protein S24 | -0.042954 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0418513 |
| VCL | vinculin | -0.041777 |
| DUSP6 | dual specificity phosphatase 6 | -0.0416796 |
| PFN1 | profilin 1 | -0.0402298 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0397292 |
| BCL2L1 | BCL2-like 1 | -0.0392154 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0389611 |
| RPS23 | ribosomal protein S23 | -0.0389129 |
| RPL36A | ribosomal protein L36a | -0.038771 |
| RPLP0 | ribosomal protein, large, P0 | -0.038649 |
| BPTF | bromodomain PHD finger transcription factor | -0.0377722 |
| ENO1 | enolase 1, (alpha) | -0.0377159 |
| PGK1 | phosphoglycerate kinase 1 | -0.0375281 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0374708 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.037448 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0374227 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0372343 |
| SYT1 | synaptotagmin I | -0.037209 |
| CBX3 | chromobox homolog 3 | -0.0371813 |
| RUNX1 | runt-related transcription factor 1 | -0.0364533 |
| S100A10 | S100 calcium binding protein A10 | -0.035704 |
| OXR1 | oxidation resistance 1 | -0.0356928 |
| KPNB1 | karyopherin (importin) beta 1 | -0.035609 |
| RPL37 | ribosomal protein L37 | -0.0351563 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0349683 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0349136 |
| SPATA13 | spermatogenesis associated 13 | -0.0348313 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0345934 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0345352 |
| RPS21 | ribosomal protein S21 | -0.0344457 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0343409 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0343296 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0339864 |
| GLG1 | golgi glycoprotein 1 | -0.0338374 |
| RPS19 | ribosomal protein S19 | -0.0337768 |
| HMGB1 | high mobility group box 1 | -0.0335649 |
| ITGB4 | integrin, beta 4 | -0.0334468 |
| FTL | ferritin, light polypeptide | -0.0332197 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0330069 |
| RPL12 | ribosomal protein L12 | -0.0326857 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0325454 |
| DEK | DEK proto-oncogene | -0.0325176 |
| RPL5 | ribosomal protein L5 | -0.0324701 |
| RPL38 | ribosomal protein L38 | -0.0321035 |
| RPL19 | ribosomal protein L19 | -0.0320949 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0316641 |
| ABLIM1 | actin binding LIM protein 1 | -0.0315677 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0308367 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0307318 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0307058 |
| RPL9 | ribosomal protein L9 | -0.0304674 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0304421 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0303022 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0297709 |
| KRT8 | keratin 8, type II | -0.0296349 |
| FRMD5 | FERM domain containing 5 | -0.0296051 |
