| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.133978 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0619907 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0597271 |
| FAM13A | family with sequence similarity 13, member A | 0.0577892 |
| SPAG9 | sperm associated antigen 9 | 0.0570722 |
| NDRG1 | N-myc downstream regulated 1 | 0.0552251 |
| STC1 | stanniocalcin 1 | 0.0496714 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0456775 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0443296 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0438721 |
| TPM3 | tropomyosin 3 | 0.0374391 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0370018 |
| NUP58 | nucleoporin 58 | 0.0355612 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0354397 |
| HELZ | helicase with zinc finger | 0.0345742 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0333827 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0322962 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0321253 |
| GOLGA4 | golgin A4 | 0.0320777 |
| SNX9 | sorting nexin 9 | 0.0317186 |
| ANXA5 | annexin A5 | 0.0299269 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0296401 |
| FNDC3B | fibronectin type III domain containing 3B | 0.029578 |
| KLF6 | Kruppel-like factor 6 | 0.0292472 |
| MEIS1 | Meis homeobox 1 | 0.0288674 |
| USP3 | ubiquitin specific peptidase 3 | 0.0284694 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.027879 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.02709 |
| RNF145 | ring finger protein 145 | 0.0266834 |
| RAB8B | RAB8B, member RAS oncogene family | 0.026262 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0262245 |
| NCKAP1 | NCK-associated protein 1 | 0.0255476 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.025511 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0254873 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0249467 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0248906 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0237825 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0236911 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0234829 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0229817 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.022957 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0229107 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0225333 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0223392 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.021785 |
| COG5 | component of oligomeric golgi complex 5 | 0.0216988 |
| RPL3 | ribosomal protein L3 | 0.0214263 |
| FMNL2 | formin-like 2 | 0.0214256 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0210816 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0206527 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0206328 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0205719 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0205368 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0204987 |
| RAI1 | retinoic acid induced 1 | 0.0204945 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0204029 |
| RND3 | Rho family GTPase 3 | 0.0203303 |
| RHOA | ras homolog family member A | 0.0202658 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0202175 |
| SFXN1 | sideroflexin 1 | 0.0200805 |
| YBX3 | Y box binding protein 3 | 0.0199206 |
| EZR | ezrin | 0.0198991 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0197438 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0195668 |
| CCNY | cyclin Y | 0.0194033 |
| RYBP | RING1 and YY1 binding protein | 0.0193929 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0192205 |
| COPA | coatomer protein complex, subunit alpha | 0.0189687 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0189657 |
| VMP1 | vacuole membrane protein 1 | 0.0188784 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0188717 |
| PDGFC | platelet derived growth factor C | 0.0187907 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.018777 |
| NBAS | neuroblastoma amplified sequence | 0.0187473 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0185688 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0184445 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0184096 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0183748 |
| ANLN | anillin, actin binding protein | 0.0183586 |
| MSI2 | musashi RNA-binding protein 2 | 0.0182465 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0179778 |
| AXL | AXL receptor tyrosine kinase | 0.0179503 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0178879 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0178613 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0178186 |
| KLC1 | kinesin light chain 1 | 0.0178084 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0177192 |
| ADM | adrenomedullin | 0.017646 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0175168 |
| FBXO42 | F-box protein 42 | 0.0173244 |
| SUCO | SUN domain containing ossification factor | 0.0173055 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0171984 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0170552 |
| XPO1 | exportin 1 | 0.0169845 |
| RHOB | ras homolog family member B | 0.0169544 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0169539 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0167701 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0167699 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0165713 |
| OGA | O-GlcNAcase | 0.0164862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.207803 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.195239 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.178777 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166672 |
| VIM | vimentin | -0.160204 |
| HMGA2 | high mobility group AT-hook 2 | -0.154072 |
| COL6A3 | collagen, type VI, alpha 3 | -0.133518 |
| FN1 | fibronectin 1 | -0.119576 |
| HLA-B | major histocompatibility complex, class I, B | -0.115123 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.107235 |
| MYO10 | myosin X | -0.105934 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.102761 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.101123 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.097128 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0951325 |
| ASPH | aspartate beta-hydroxylase | -0.0866177 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0840123 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0752535 |
| ACTG1 | actin gamma 1 | -0.0734867 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0728493 |
| VCL | vinculin | -0.0647538 |
| CAVIN1 | caveolae associated protein 1 | -0.0631519 |
| OXR1 | oxidation resistance 1 | -0.0626302 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0603074 |
| CDH13 | cadherin 13 | -0.0583626 |
| NAV1 | neuron navigator 1 | -0.0540194 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0519741 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0508528 |
| COL1A2 | collagen, type I, alpha 2 | -0.0503059 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0497796 |
| FRMD4A | FERM domain containing 4A | -0.0469954 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0465579 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0465332 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0465064 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0455035 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0445527 |
| GLIS3 | GLIS family zinc finger 3 | -0.0438952 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0437113 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0421557 |
| RAI14 | retinoic acid induced 14 | -0.041214 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0411519 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0410546 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0403604 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0390685 |
| INHBA | inhibin, beta A | -0.0383782 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0381237 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0381201 |
| RPS6 | ribosomal protein S6 | -0.0380901 |
| OSMR | oncostatin M receptor | -0.0379417 |
| TPM4 | tropomyosin 4 | -0.0374035 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0373623 |
| TMSB10 | thymosin beta 10 | -0.0370413 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0370198 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0365943 |
| RPL35A | ribosomal protein L35a | -0.0365572 |
| MMP1 | matrix metallopeptidase 1 | -0.0361221 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0352921 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0349103 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0348436 |
| B2M | beta-2-microglobulin | -0.0345231 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0338072 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0334528 |
| IGF2 | insulin-like growth factor 2 | -0.0332074 |
| CALD1 | caldesmon 1 | -0.0323662 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0321598 |
| POTEF | POTE ankyrin domain family, member F | -0.0318301 |
| EGFR | epidermal growth factor receptor | -0.0318062 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0316815 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0314548 |
| EMP1 | epithelial membrane protein 1 | -0.0311887 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0311715 |
| VCAN | versican | -0.0310236 |
| DIAPH2 | diaphanous-related formin 2 | -0.0307724 |
| RPS8 | ribosomal protein S8 | -0.0300608 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0299721 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0298191 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0293894 |
| SMYD3 | SET and MYND domain containing 3 | -0.0290163 |
| PARD3 | par-3 family cell polarity regulator | -0.0283335 |
| CCND1 | cyclin D1 | -0.0271616 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0270057 |
| RPL38 | ribosomal protein L38 | -0.0259492 |
| AHNAK | AHNAK nucleoprotein | -0.0258884 |
| COL3A1 | collagen, type III, alpha 1 | -0.02567 |
| HLA-A | major histocompatibility complex, class I, A | -0.025246 |
| RSU1 | Ras suppressor protein 1 | -0.0252343 |
| PRSS23 | protease, serine, 23 | -0.0250643 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0250399 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0250086 |
| RPS24 | ribosomal protein S24 | -0.0249509 |
| INTS6 | integrator complex subunit 6 | -0.0247076 |
| RPL31 | ribosomal protein L31 | -0.0245407 |
| RPL34 | ribosomal protein L34 | -0.0245202 |
| PRR16 | proline rich 16 | -0.0242254 |
| AEBP2 | AE binding protein 2 | -0.0241331 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0240652 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0240198 |
| SEPTIN9 | septin 9 | -0.0238277 |
| CCDC102B | coiled-coil domain containing 102B | -0.0234112 |
| MCL1 | myeloid cell leukemia 1 | -0.0233146 |
