Pituitary-Dependent Cushing'S Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0221406
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Genes

109 genes associated with the disease Pituitary-Dependent Cushing'S Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AGRP agouti related neuropeptide
AIP aryl hydrocarbon receptor interacting protein
APOA1 apolipoprotein A-I
APOB apolipoprotein B
ARHGAP24 Rho GTPase activating protein 24
AVPR1B arginine vasopressin receptor 1B
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD2 bromodomain containing 2
CABLES1 Cdk5 and Abl enzyme substrate 1
CCND1 cyclin D1
CD14 CD14 molecule
CD274 CD274 molecule
CDH23 cadherin-related 23
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK2 checkpoint kinase 2
CIB1 calcium and integrin binding 1 (calmyrin)
CIRBP cold inducible RNA binding protein
CNTN3 contactin 3 (plasmacytoma associated)
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CRH corticotropin releasing hormone
CRHBP corticotropin releasing hormone binding protein
CRHR1 corticotropin releasing hormone receptor 1
CRISP2 cysteine-rich secretory protein 2
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DICER1 dicer 1, ribonuclease type III
DRD2 dopamine receptor D2
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPHB2 EPH receptor B2
FGFR4 fibroblast growth factor receptor 4
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIP gastric inhibitory polypeptide
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAS GNAS complex locus
HDAC2 histone deacetylase 2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL6 interleukin 6
KLK3 kallikrein-related peptidase 3
KRT5 keratin 5, type II
LIFR leukemia inhibitory factor receptor alpha
LPXN leupaxin
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MED7 mediator complex subunit 7
MEN1 multiple endocrine neoplasia I
MGC57346-CRHR1 MGC57346-CRHR1 readthrough
MGMT O-6-methylguanine-DNA methyltransferase
MOCOS molybdenum cofactor sulfurase
MSH2 mutS homolog 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEUROD1 neuronal differentiation 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PAX7 paired box 7
PCNA proliferating cell nuclear antigen
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
POMC proopiomelanocortin
POU1F1 POU class 1 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
PRSS55 protease, serine, 55
SCG5 secretogranin V
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP2 secreted frizzled-related protein 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMCP sperm mitochondria-associated cysteine-rich protein
SMS spermine synthase
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SP1 Sp1 transcription factor
SPZ1 spermatogenic leucine zipper 1
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX19 T-box 19
THBS1 thrombospondin 1
TP53 tumor protein p53
TP73 tumor protein p73
USP48 ubiquitin specific peptidase 48
USP8 ubiquitin specific peptidase 8
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
ZC4H2 zinc finger, C4H2 domain containing