Pleural Tuberculosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac. (Human Disease Ontology, DOID_106)
External Link https://www.disgenet.org/browser/0/1/0/C0041326
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Genes

55 genes associated with the disease Pleural Tuberculosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADA adenosine deaminase
BST1 bone marrow stromal cell antigen 1
BTLA B and T lymphocyte associated
CAMP cathelicidin antimicrobial peptide
CAPN1 calpain 1, (mu/I) large subunit
CCL2 chemokine (C-C motif) ligand 2
CCL8 chemokine (C-C motif) ligand 8
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD163 CD163 molecule
CD19 CD19 molecule
CD274 CD274 molecule
CD83 CD83 molecule
CFP complement factor properdin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
FHIT fragile histidine triad
FOXP3 forkhead box P3
GIF gastric intrinsic factor (vitamin B synthesis)
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL10 interleukin 10
IL17D interleukin 17D
IL18 interleukin 18
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
IL26 interleukin 26
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
INTS4 integrator complex subunit 4
ISG20 interferon stimulated exonuclease gene 20kDa
LAMP3 lysosomal-associated membrane protein 3
LSAMP limbic system-associated membrane protein
MAX MYC associated factor X
MYDGF myeloid-derived growth factor
NCAPG2 non-SMC condensin II complex, subunit G2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PEPD peptidase D
RHOF ras homolog family member F (in filopodia)
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
ROMO1 reactive oxygen species modulator 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SOCS3 suppressor of cytokine signaling 3
TGFB1 transforming growth factor, beta 1
THEMIS thymocyte selection associated
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT3 wingless-type MMTV integration site family, member 3