Pleurisy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A pleural disease that is characterized by inflammation of the pleura, the lining of the pleural cavity surrounding the lungs. (Human Disease Ontology, DOID_10247)
External Link https://www.disgenet.org/browser/0/1/0/C0032231
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Genes

77 genes associated with the disease Pleurisy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADA adenosine deaminase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C4A complement component 4A (Rodgers blood group)
CCL2 chemokine (C-C motif) ligand 2
CCR1 chemokine (C-C motif) receptor 1
CCR4 chemokine (C-C motif) receptor 4
CD4 CD4 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCR3 chemokine (C-X-C motif) receptor 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAH11 dynein, axonemal, heavy chain 11
DNASE1 deoxyribonuclease I
ERAP1 endoplasmic reticulum aminopeptidase 1
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
HAVCR1 hepatitis A virus cellular receptor 1
HLA-B major histocompatibility complex, class I, B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL10 interleukin 10
IL12A interleukin 12A
IL17A interleukin 17A
IL1B interleukin 1, beta
IL2 interleukin 2
IL23R interleukin 23 receptor
IL4 interleukin 4
IL6 interleukin 6
INTS4 integrator complex subunit 4
KEAP1 kelch-like ECH-associated protein 1
KLK3 kallikrein-related peptidase 3
KLRC4 killer cell lectin-like receptor subfamily C, member 4
LAG3 lymphocyte-activation gene 3
MEFV Mediterranean fever
MPO myeloperoxidase
MTAP methylthioadenosine phosphorylase
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOX4 NADPH oxidase 4
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G10 phospholipase A2, group X
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RBM45 RNA binding motif protein 45
RORC RAR-related orphan receptor C
RPS19 ribosomal protein S19
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH2B2 SH2B adaptor protein 2
SIRT1 sirtuin 1
SSB Sjogren syndrome antigen B (autoantigen La)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STMN1 stathmin 1
TIMELESS timeless circadian clock
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TREX1 three prime repair exonuclease 1
UBAC2 UBA domain containing 2
WNT3 wingless-type MMTV integration site family, member 3