| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.168428 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.160283 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.121316 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120004 |
| PTMA | prothymosin, alpha | 0.117541 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.11349 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.100147 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0780653 |
| CANX | calnexin | 0.0729141 |
| VIM | vimentin | 0.0684723 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0637988 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0626601 |
| GOLGA4 | golgin A4 | 0.0580527 |
| PGK1 | phosphoglycerate kinase 1 | 0.0557182 |
| SQSTM1 | sequestosome 1 | 0.0544664 |
| NAV2 | neuron navigator 2 | 0.0540756 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0515211 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0491116 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0490473 |
| CALR | calreticulin | 0.0483271 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0475048 |
| MSN | moesin | 0.0472771 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0472473 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0468549 |
| POTEF | POTE ankyrin domain family, member F | 0.0466171 |
| APP | amyloid beta (A4) precursor protein | 0.0461776 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0450193 |
| TMSB4X | thymosin beta 4, X-linked | 0.0448771 |
| SETD5 | SET domain containing 5 | 0.0442518 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0434809 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0431948 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.042917 |
| ATP13A3 | ATPase type 13A3 | 0.042209 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0419267 |
| MYOF | myoferlin | 0.0405057 |
| CD109 | CD109 molecule | 0.0403868 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0397741 |
| ENO1 | enolase 1, (alpha) | 0.0392289 |
| MATR3 | matrin 3 | 0.0384524 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0380021 |
| INSIG2 | insulin induced gene 2 | 0.0379778 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0373772 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0367396 |
| ZNF292 | zinc finger protein 292 | 0.036668 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0365127 |
| HELZ | helicase with zinc finger | 0.036143 |
| TPM3 | tropomyosin 3 | 0.0359638 |
| C1D | C1D nuclear receptor corepressor | 0.0354749 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353553 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0349434 |
| OGA | O-GlcNAcase | 0.0346605 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0346329 |
| XPO1 | exportin 1 | 0.0335416 |
| B2M | beta-2-microglobulin | 0.0335239 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0333084 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.03329 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0331055 |
| SPAG9 | sperm associated antigen 9 | 0.0325738 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0325649 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0325521 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0324541 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0321579 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0320477 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0317026 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0309991 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0309164 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0307529 |
| ERBIN | erbb2 interacting protein | 0.0301193 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0299074 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0295291 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0293983 |
| LOXL2 | lysyl oxidase-like 2 | 0.0293338 |
| MSI2 | musashi RNA-binding protein 2 | 0.0291352 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0291215 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0290127 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0288838 |
| LDHA | lactate dehydrogenase A | 0.0286632 |
| SUCO | SUN domain containing ossification factor | 0.0284215 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0282945 |
| HMGB2 | high mobility group box 2 | 0.0282069 |
| VEGFA | vascular endothelial growth factor A | 0.0276879 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0275633 |
| FLNB | filamin B, beta | 0.0275618 |
| RNF24 | ring finger protein 24 | 0.0273953 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.027326 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0272068 |
| DTNA | dystrobrevin, alpha | 0.0265077 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0261687 |
| ANO6 | anoctamin 6 | 0.0261609 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0261487 |
| HDAC9 | histone deacetylase 9 | 0.0259703 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0259482 |
| FAM107B | family with sequence similarity 107, member B | 0.0259102 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0258893 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0258441 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0257947 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0257057 |
| RAI1 | retinoic acid induced 1 | 0.0255922 |
| NGLY1 | N-glycanase 1 | 0.0255877 |
| COPA | coatomer protein complex, subunit alpha | 0.0255805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295895 |
| MT2A | metallothionein 2A | -0.128428 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.117273 |
| TMSB10 | thymosin beta 10 | -0.112042 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.106236 |
| LOX | lysyl oxidase | -0.0758355 |
| PLAT | plasminogen activator, tissue | -0.0700374 |
| HLA-B | major histocompatibility complex, class I, B | -0.0659922 |
| ANXA2 | annexin A2 | -0.061679 |
| MAP1B | microtubule-associated protein 1B | -0.0611835 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0602268 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0578164 |
| PODXL | podocalyxin-like | -0.057575 |
| NAV1 | neuron navigator 1 | -0.055358 |
| MT1X | metallothionein 1X | -0.0486336 |
| RIGI | RNA sensor RIG-I | -0.0477396 |
| CD44 | CD44 molecule (Indian blood group) | -0.0476976 |
| CD99 | CD99 molecule | -0.0450524 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0441497 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.043291 |
| GLIS3 | GLIS family zinc finger 3 | -0.0428467 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0423732 |
| HLA-C | major histocompatibility complex, class I, C | -0.0403714 |
| THBS2 | thrombospondin 2 | -0.0398913 |
| CAVIN1 | caveolae associated protein 1 | -0.0378882 |
| COL3A1 | collagen, type III, alpha 1 | -0.0365545 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0363915 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0357236 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0327449 |
| COL1A2 | collagen, type I, alpha 2 | -0.0313724 |
| LMNA | lamin A/C | -0.0311522 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0303391 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0283753 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.02829 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0282709 |
| SP100 | SP100 nuclear antigen | -0.0280412 |
| MX2 | MX dynamin-like GTPase 2 | -0.0273164 |
| PRSS23 | protease, serine, 23 | -0.0268214 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0265333 |
| HDLBP | high density lipoprotein binding protein | -0.0263695 |
| FTL | ferritin, light polypeptide | -0.0263694 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0259121 |
| CTSB | cathepsin B | -0.025574 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0253345 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0251621 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0248556 |
| S100A10 | S100 calcium binding protein A10 | -0.0245234 |
| RPS15 | ribosomal protein S15 | -0.0241022 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0236477 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0234614 |
| PLXNA2 | plexin A2 | -0.0228372 |
| AUTS2 | autism susceptibility candidate 2 | -0.0228339 |
| TXNIP | thioredoxin interacting protein | -0.022784 |
| SLC38A1 | solute carrier family 38, member 1 | -0.022243 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0221811 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221143 |
| RPL23 | ribosomal protein L23 | -0.0217332 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0217182 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0216185 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0215174 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0214372 |
| LAMB1 | laminin, beta 1 | -0.0210788 |
| RRBP1 | ribosome binding protein 1 | -0.0210272 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0209485 |
| TMEM263 | transmembrane protein 263 | -0.0208071 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0207265 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0206658 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.020598 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0203397 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0202757 |
| VCL | vinculin | -0.0201324 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0200975 |
| CDK12 | cyclin-dependent kinase 12 | -0.0200161 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0198417 |
| FUS | FUS RNA binding protein | -0.0197785 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0197568 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0193531 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0189451 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0187247 |
| EGR1 | early growth response 1 | -0.0185838 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0184954 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0184224 |
| RASAL2 | RAS protein activator like 2 | -0.0182424 |
| RPL35A | ribosomal protein L35a | -0.0180386 |
| GANAB | glucosidase, alpha; neutral AB | -0.0177864 |
| COL5A1 | collagen, type V, alpha 1 | -0.0176567 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0175195 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0174693 |
| TLE4 | transducin-like enhancer of split 4 | -0.0174089 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0173894 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0173371 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0172417 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0172143 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.016974 |
| RTN4 | reticulon 4 | -0.0169723 |
| THY1 | Thy-1 cell surface antigen | -0.0169113 |
| NPR2 | natriuretic peptide receptor 2 | -0.016873 |
| CYTH3 | cytohesin 3 | -0.0168395 |
| KIAA1549L | KIAA1549-like | -0.0166645 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0166449 |
