| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.128891 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0898906 |
| VIM | vimentin | 0.0780001 |
| FAM13A | family with sequence similarity 13, member A | 0.0733338 |
| RPS6 | ribosomal protein S6 | 0.0606763 |
| RPL35A | ribosomal protein L35a | 0.0580454 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0497666 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0487501 |
| B2M | beta-2-microglobulin | 0.0472211 |
| RNF145 | ring finger protein 145 | 0.0413034 |
| HELZ | helicase with zinc finger | 0.0405079 |
| RPL19 | ribosomal protein L19 | 0.0387178 |
| RPL36A | ribosomal protein L36a | 0.038342 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0381794 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0370765 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0368381 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0367117 |
| ENO1 | enolase 1, (alpha) | 0.0366718 |
| RPS12 | ribosomal protein S12 | 0.0366564 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0365724 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0360974 |
| NDRG1 | N-myc downstream regulated 1 | 0.0358955 |
| RPLP0 | ribosomal protein, large, P0 | 0.0341289 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337409 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0332649 |
| RPS8 | ribosomal protein S8 | 0.033013 |
| RPL26 | ribosomal protein L26 | 0.0319584 |
| SPAG9 | sperm associated antigen 9 | 0.0318176 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0313494 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0306001 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0305826 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0299085 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.029156 |
| HMGB2 | high mobility group box 2 | 0.0288124 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0283833 |
| RPS3 | ribosomal protein S3 | 0.028123 |
| NOP58 | NOP58 ribonucleoprotein | 0.0280051 |
| RPL31 | ribosomal protein L31 | 0.0277532 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.027516 |
| RACK1 | receptor for activated C kinase 1 | 0.0274133 |
| RPLP1 | ribosomal protein, large, P1 | 0.0268868 |
| PGK1 | phosphoglycerate kinase 1 | 0.0263622 |
| NGLY1 | N-glycanase 1 | 0.0259145 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0258464 |
| RPL37A | ribosomal protein L37a | 0.0252107 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0251794 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0250593 |
| RPL7 | ribosomal protein L7 | 0.02478 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0242962 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0241986 |
| COG5 | component of oligomeric golgi complex 5 | 0.0241268 |
| RPS27A | ribosomal protein S27a | 0.0239451 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0239187 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0237986 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0236723 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0236127 |
| ZNF292 | zinc finger protein 292 | 0.0235117 |
| TPR | translocated promoter region, nuclear basket protein | 0.0234311 |
| S100A6 | S100 calcium binding protein A6 | 0.0232593 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0232178 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0231981 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0227172 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.022648 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0225844 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0225665 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0225096 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0223317 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0221505 |
| RPS16 | ribosomal protein S16 | 0.0220907 |
| TMSB10 | thymosin beta 10 | 0.0218144 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.021781 |
| DTNA | dystrobrevin, alpha | 0.0217478 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0215671 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0214063 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0213717 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0213155 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0212344 |
| RBM25 | RNA binding motif protein 25 | 0.021179 |
| RPL37 | ribosomal protein L37 | 0.0210708 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0208719 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0207712 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0207387 |
| TRIM33 | tripartite motif containing 33 | 0.0206459 |
| CBX3 | chromobox homolog 3 | 0.0203995 |
| RPS11 | ribosomal protein S11 | 0.0202587 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.020129 |
| RPL7A | ribosomal protein L7a | 0.0201243 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0201235 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0201044 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198494 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0197823 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0195238 |
| NUP58 | nucleoporin 58 | 0.0194448 |
| RPL18 | ribosomal protein L18 | 0.0190916 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0189931 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0189016 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0188655 |
| MT2A | metallothionein 2A | 0.0188132 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0187788 |
| CDC27 | cell division cycle 27 | 0.0187736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.14399 |
| FMN1 | formin 1 | -0.116023 |
| SYT1 | synaptotagmin I | -0.108133 |
| MEIS2 | Meis homeobox 2 | -0.0860248 |
| NRG1 | neuregulin 1 | -0.0841978 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0761342 |
| IGF2 | insulin-like growth factor 2 | -0.0751108 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0695874 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.06927 |
| LSAMP | limbic system-associated membrane protein | -0.0677411 |
| TRIB2 | tribbles pseudokinase 2 | -0.0653669 |
| LPIN1 | lipin 1 | -0.0606674 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0580189 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0568694 |
| KLHL13 | kelch-like family member 13 | -0.0538245 |
| RNF213 | ring finger protein 213 | -0.0518713 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0511881 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0488905 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0469801 |
| FRMD4A | FERM domain containing 4A | -0.0464309 |
| TLE4 | transducin-like enhancer of split 4 | -0.0410524 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0407533 |
| COL1A1 | collagen, type I, alpha 1 | -0.0392529 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0386807 |
| DPH6 | diphthamine biosynthesis 6 | -0.0374299 |
| PLPP1 | phospholipid phosphatase 1 | -0.034532 |
| SMYD3 | SET and MYND domain containing 3 | -0.0340627 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0337099 |
| MAP1B | microtubule-associated protein 1B | -0.0335701 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0322482 |
| ANGPT1 | angiopoietin 1 | -0.0320645 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.030441 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0297213 |
| NREP | neuronal regeneration related protein | -0.0293728 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0291749 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0291193 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.028906 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0285681 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0281804 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0277147 |
| VCL | vinculin | -0.0276853 |
| GLI3 | GLI family zinc finger 3 | -0.0271943 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0271855 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0271074 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0270864 |
| COL3A1 | collagen, type III, alpha 1 | -0.026634 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0262601 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0257294 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0255641 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.024289 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0242279 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.024175 |
| ZNF804A | zinc finger protein 804A | -0.0236833 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.0235742 |
| TULP4 | tubby like protein 4 | -0.0234749 |
| PCBP2 | poly(rC) binding protein 2 | -0.0234026 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0231334 |
| SEPTIN9 | septin 9 | -0.0231 |
| NRP1 | neuropilin 1 | -0.0228236 |
| CSNK1D | casein kinase 1, delta | -0.0226995 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.022449 |
| SIK2 | salt-inducible kinase 2 | -0.0223694 |
| AOPEP | aminopeptidase O (putative) | -0.0220551 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0219202 |
| GPC5 | glypican 5 | -0.0218554 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0216957 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0216676 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0215924 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0214816 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0213777 |
| RALYL | RALY RNA binding protein-like | -0.0212161 |
| EPHA3 | EPH receptor A3 | -0.0211709 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0211048 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0209349 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0208951 |
| MSI2 | musashi RNA-binding protein 2 | -0.0207059 |
| PCNX4 | pecanex 4 | -0.0205362 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0204178 |
| GLG1 | golgi glycoprotein 1 | -0.0203079 |
| TENM4 | teneurin transmembrane protein 4 | -0.0201979 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0200474 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0200283 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0199381 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0198924 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0198902 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0198743 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0196845 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.019682 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0196394 |
| PTEN | phosphatase and tensin homolog | -0.019609 |
| DUSP10 | dual specificity phosphatase 10 | -0.0196044 |
| ADNP | activity-dependent neuroprotector homeobox | -0.019478 |
| ZNF652 | zinc finger protein 652 | -0.0194392 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.019148 |
| HAS2 | hyaluronan synthase 2 | -0.0190583 |
| GLCCI1 | glucocorticoid induced 1 | -0.0190103 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0189054 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0186919 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0186397 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0184341 |
