| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0747068 |
| ATP13A3 | ATPase type 13A3 | 0.0533622 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0532397 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0443735 |
| SMAD3 | SMAD family member 3 | 0.0424044 |
| CADM1 | cell adhesion molecule 1 | 0.0397374 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0326887 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0306513 |
| SPAG9 | sperm associated antigen 9 | 0.0298531 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0293882 |
| APP | amyloid beta (A4) precursor protein | 0.0281674 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0275045 |
| CANX | calnexin | 0.0269874 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0263108 |
| PCBP2 | poly(rC) binding protein 2 | 0.0260063 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0254997 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.024666 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0245695 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0237372 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0236005 |
| PTMA | prothymosin, alpha | 0.0235328 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0234383 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0229065 |
| LOXL2 | lysyl oxidase-like 2 | 0.0227039 |
| ZNF292 | zinc finger protein 292 | 0.022496 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0223544 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0221366 |
| ARRDC3 | arrestin domain containing 3 | 0.0220829 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0219319 |
| MRTFA | myocardin related transcription factor A | 0.0211425 |
| MATR3 | matrin 3 | 0.0210571 |
| RPL3 | ribosomal protein L3 | 0.0206016 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0205106 |
| RASA2 | RAS p21 protein activator 2 | 0.0197322 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0196225 |
| OGA | O-GlcNAcase | 0.0194413 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0193146 |
| VEGFA | vascular endothelial growth factor A | 0.0189917 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0182099 |
| PLEC | plectin | 0.0178359 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0171786 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0170795 |
| SETD5 | SET domain containing 5 | 0.017057 |
| CCNY | cyclin Y | 0.0170323 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0168546 |
| TMF1 | TATA element modulatory factor 1 | 0.0168083 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0167804 |
| RPS18 | ribosomal protein S18 | 0.0164952 |
| GOLGA4 | golgin A4 | 0.0164896 |
| PDE10A | phosphodiesterase 10A | 0.0164571 |
| FMNL2 | formin-like 2 | 0.01636 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0162804 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0162227 |
| XPO1 | exportin 1 | 0.0161992 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.016185 |
| RNF145 | ring finger protein 145 | 0.0161645 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0161067 |
| TPM3 | tropomyosin 3 | 0.0160924 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0160853 |
| MTSS1 | metastasis suppressor 1 | 0.0156824 |
| PTK2 | protein tyrosine kinase 2 | 0.0156295 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0154163 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0150116 |
| CCNL1 | cyclin L1 | 0.014941 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0146125 |
| MSN | moesin | 0.0145687 |
| RYK | receptor-like tyrosine kinase | 0.0143995 |
| KIF1B | kinesin family member 1B | 0.0143895 |
| DENND5A | DENN/MADD domain containing 5A | 0.0142317 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0142095 |
| RLF | rearranged L-myc fusion | 0.0141732 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0141182 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0139519 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.013806 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0134327 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0132585 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0132508 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0131943 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0130528 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0130144 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0129481 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0129299 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0128387 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0128164 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0127266 |
| HELZ | helicase with zinc finger | 0.0126748 |
| PRELID2 | PRELI domain containing 2 | 0.0126596 |
| USP3 | ubiquitin specific peptidase 3 | 0.012655 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0126231 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.012611 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0125507 |
| ZNF148 | zinc finger protein 148 | 0.0125507 |
| FAM13A | family with sequence similarity 13, member A | 0.0124181 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.012361 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.012355 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0123547 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.012339 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0123366 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0123184 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0122992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.338816 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.28284 |
| FN1 | fibronectin 1 | -0.210361 |
| COL1A1 | collagen, type I, alpha 1 | -0.20504 |
| VIM | vimentin | -0.159976 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.136092 |
| TMSB10 | thymosin beta 10 | -0.0985662 |
| COL1A2 | collagen, type I, alpha 2 | -0.0976795 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0940847 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0778279 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0741496 |
| FTL | ferritin, light polypeptide | -0.066436 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.060359 |
| IER3 | immediate early response 3 | -0.0582059 |
| NDRG1 | N-myc downstream regulated 1 | -0.0574384 |
| ACTG1 | actin gamma 1 | -0.0572564 |
| MT2A | metallothionein 2A | -0.0551726 |
| CDH13 | cadherin 13 | -0.0533199 |
| FBN1 | fibrillin 1 | -0.0489213 |
| CALD1 | caldesmon 1 | -0.0450706 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0434782 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0408593 |
| GLIS3 | GLIS family zinc finger 3 | -0.0399907 |
| LOX | lysyl oxidase | -0.0393407 |
| S100A9 | S100 calcium binding protein A9 | -0.0383249 |
| RPL35A | ribosomal protein L35a | -0.0381304 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0366871 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.036559 |
| EXT1 | exostosin glycosyltransferase 1 | -0.035507 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0343959 |
| HLA-B | major histocompatibility complex, class I, B | -0.0340997 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0339573 |
| TPM4 | tropomyosin 4 | -0.0338439 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0337619 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0334795 |
| RPL8 | ribosomal protein L8 | -0.0334187 |
| RPS8 | ribosomal protein S8 | -0.0321662 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0320707 |
| MAP1B | microtubule-associated protein 1B | -0.031864 |
| CD44 | CD44 molecule (Indian blood group) | -0.0318418 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0312702 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0311916 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0310356 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.030725 |
| ASPH | aspartate beta-hydroxylase | -0.0303159 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0301238 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.029521 |
| VCAN | versican | -0.0282178 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0281979 |
| LDHA | lactate dehydrogenase A | -0.0274542 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0270071 |
| EGR1 | early growth response 1 | -0.025753 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0253823 |
| CTSB | cathepsin B | -0.0253187 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0248507 |
| RPL28 | ribosomal protein L28 | -0.024598 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0244781 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0237684 |
| ANXA2 | annexin A2 | -0.023541 |
| PFN1 | profilin 1 | -0.0234709 |
| CLMP | CXADR-like membrane protein | -0.023295 |
| COL5A1 | collagen, type V, alpha 1 | -0.0228251 |
| S100A10 | S100 calcium binding protein A10 | -0.0227318 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0226161 |
| THY1 | Thy-1 cell surface antigen | -0.0226032 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0222451 |
| POTEF | POTE ankyrin domain family, member F | -0.0222204 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0220696 |
| CNTN5 | contactin 5 | -0.0218136 |
| OSMR | oncostatin M receptor | -0.021675 |
| MT1X | metallothionein 1X | -0.0211014 |
| RRBP1 | ribosome binding protein 1 | -0.0209778 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0208745 |
| FOXP1 | forkhead box P1 | -0.0203864 |
| SDC2 | syndecan 2 | -0.0203313 |
| PXDN | peroxidasin | -0.0194129 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0193595 |
| NRP1 | neuropilin 1 | -0.0192083 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.019119 |
| S100A6 | S100 calcium binding protein A6 | -0.0187179 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0186127 |
| POSTN | periostin, osteoblast specific factor | -0.0183251 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0180957 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0180699 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0177956 |
| VCL | vinculin | -0.0177633 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0176996 |
| CD99 | CD99 molecule | -0.0176532 |
| CALU | calumenin | -0.0176332 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0175779 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0175217 |
| GOLGB1 | golgin B1 | -0.0172096 |
| NEK10 | NIMA-related kinase 10 | -0.0171905 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0171138 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0171122 |
| RPS11 | ribosomal protein S11 | -0.0170554 |
| TPI1 | triosephosphate isomerase 1 | -0.0170047 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0169948 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0167895 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0166414 |
