| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.101512 |
| IGF2 | insulin-like growth factor 2 | 0.0997934 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0827049 |
| C3 | complement component 3 | 0.0747338 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0665716 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0584097 |
| PCBP2 | poly(rC) binding protein 2 | 0.0560616 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0540403 |
| INSIG2 | insulin induced gene 2 | 0.0502596 |
| PLIN2 | perilipin 2 | 0.0501988 |
| VEGFA | vascular endothelial growth factor A | 0.0488154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0431964 |
| NDRG1 | N-myc downstream regulated 1 | 0.0414836 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0374629 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0333877 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0333053 |
| TF | transferrin | 0.0322427 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0322297 |
| AFDN | afadin, adherens junction formation factor | 0.0318579 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0316951 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0316803 |
| PTMA | prothymosin, alpha | 0.0315933 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0314027 |
| DSPP | dentin sialophosphoprotein | 0.0313927 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0310561 |
| HMGA1 | high mobility group AT-hook 1 | 0.0301955 |
| GOLGA4 | golgin A4 | 0.0293253 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0290764 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0289552 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0286584 |
| GK | glycerol kinase | 0.028346 |
| RPS12 | ribosomal protein S12 | 0.0283235 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.028251 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0278075 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0277054 |
| RPL3 | ribosomal protein L3 | 0.0274889 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0272495 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0269696 |
| NGLY1 | N-glycanase 1 | 0.0258103 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0251621 |
| AHSG | alpha-2-HS-glycoprotein | 0.0249248 |
| SETD5 | SET domain containing 5 | 0.0248312 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0243097 |
| RBM25 | RNA binding motif protein 25 | 0.0236487 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0235357 |
| KIF1B | kinesin family member 1B | 0.023128 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0229249 |
| RPL11 | ribosomal protein L11 | 0.0220625 |
| EFNA1 | ephrin-A1 | 0.0220047 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0218973 |
| ZFP36 | ZFP36 ring finger protein | 0.0214402 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0213194 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0213093 |
| DTNA | dystrobrevin, alpha | 0.0210343 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0209504 |
| ZNF292 | zinc finger protein 292 | 0.0209218 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0207827 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0205642 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0203828 |
| CCNL1 | cyclin L1 | 0.020297 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0202627 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0202468 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0201439 |
| FAM13A | family with sequence similarity 13, member A | 0.0200344 |
| RPS18 | ribosomal protein S18 | 0.0197764 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0195793 |
| STC2 | stanniocalcin 2 | 0.0195543 |
| HELZ | helicase with zinc finger | 0.0195088 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0194515 |
| CPE | carboxypeptidase E | 0.0194308 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0193674 |
| RNF145 | ring finger protein 145 | 0.0193249 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0192221 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0187306 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0184714 |
| FMNL2 | formin-like 2 | 0.0184547 |
| LRRC1 | leucine rich repeat containing 1 | 0.0184105 |
| PTK2 | protein tyrosine kinase 2 | 0.0183594 |
| TMF1 | TATA element modulatory factor 1 | 0.0182153 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0181891 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0178777 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 0.0178652 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0178218 |
| CXXC5 | CXXC finger protein 5 | 0.0176436 |
| ADM | adrenomedullin | 0.0174348 |
| VIM | vimentin | 0.0173902 |
| RPS6 | ribosomal protein S6 | 0.0173383 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0172889 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0172803 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0171 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0169514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0169265 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0165295 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.016503 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0163762 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0162326 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0161527 |
| RNF149 | ring finger protein 149 | 0.0160003 |
| TPD52 | tumor protein D52 | 0.0159237 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0157935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.29697 |
| FN1 | fibronectin 1 | -0.240649 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131066 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.129277 |
| GPC3 | glypican 3 | -0.12087 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.101595 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0961872 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0933727 |
| UBC | ubiquitin C | -0.0844901 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0799297 |
| RPS27A | ribosomal protein S27a | -0.07967 |
| A2M | alpha-2-macroglobulin | -0.0789443 |
| GPC6 | glypican 6 | -0.0632487 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0610816 |
| SVIL | supervillin | -0.0591074 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0589715 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0589045 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.055464 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0520556 |
| ITGAV | integrin, alpha V | -0.0520391 |
| ENO1 | enolase 1, (alpha) | -0.0519732 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0504155 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0489874 |
| FRMD5 | FERM domain containing 5 | -0.047235 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0465297 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0458831 |
| RPL23 | ribosomal protein L23 | -0.0447883 |
| PTCHD4 | patched domain containing 4 | -0.0442325 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0438611 |
| AHNAK | AHNAK nucleoprotein | -0.0432555 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0430551 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0429688 |
| JUN | jun proto-oncogene | -0.0428879 |
| KRT8 | keratin 8, type II | -0.0428061 |
| RRBP1 | ribosome binding protein 1 | -0.0427504 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.042019 |
| FAT1 | FAT atypical cadherin 1 | -0.0416355 |
| FOXP1 | forkhead box P1 | -0.0413874 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.041386 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0405304 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0403321 |
| MRTFA | myocardin related transcription factor A | -0.0401541 |
| RPS24 | ribosomal protein S24 | -0.0399066 |
| VMP1 | vacuole membrane protein 1 | -0.03945 |
| VCL | vinculin | -0.0391585 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0386077 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0385909 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0376868 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0372119 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.035794 |
| ACTN4 | actinin, alpha 4 | -0.0357079 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0353482 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0349205 |
| EPAS1 | endothelial PAS domain protein 1 | -0.034268 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0339969 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0329826 |
| EHBP1 | EH domain binding protein 1 | -0.0322149 |
| TMSB10 | thymosin beta 10 | -0.0319251 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0317017 |
| TXNRD1 | thioredoxin reductase 1 | -0.0307447 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0303062 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0301137 |
| OSMR | oncostatin M receptor | -0.0299293 |
| FAM107B | family with sequence similarity 107, member B | -0.029848 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0295453 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0294813 |
| TRIM26 | tripartite motif containing 26 | -0.0292175 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0291991 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.029088 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0288774 |
| BCL2L1 | BCL2-like 1 | -0.0288626 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0288289 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0287081 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0276854 |
| IER3 | immediate early response 3 | -0.0276647 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0275952 |
| EGR1 | early growth response 1 | -0.0274773 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0274637 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.0273182 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0271499 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0264674 |
| FUS | FUS RNA binding protein | -0.026334 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.0255019 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0253505 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0250821 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.024513 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0243017 |
| RIGI | RNA sensor RIG-I | -0.0241828 |
| HDLBP | high density lipoprotein binding protein | -0.0241326 |
| FAM135A | family with sequence similarity 135, member A | -0.0239762 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0239328 |
| CNKSR3 | CNKSR family member 3 | -0.0238906 |
| PEG10 | paternally expressed 10 | -0.0238291 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0237449 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.023172 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0230743 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0230282 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0229749 |
| TNS3 | tensin 3 | -0.0229717 |
| ATP11A | ATPase, class VI, type 11A | -0.0228898 |
