| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MSN | moesin | 0.139064 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.116311 |
| PTMA | prothymosin, alpha | 0.10497 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0922873 |
| MTSS1 | metastasis suppressor 1 | 0.0872089 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0843006 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.080872 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0684003 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635436 |
| MEF2A | myocyte enhancer factor 2A | 0.0619163 |
| KRT17 | keratin 17, type I | 0.0612001 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.057931 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0576695 |
| NAV2 | neuron navigator 2 | 0.0565081 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0557147 |
| PCBP2 | poly(rC) binding protein 2 | 0.0554101 |
| PTK2 | protein tyrosine kinase 2 | 0.0520742 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0519897 |
| RAI14 | retinoic acid induced 14 | 0.0518981 |
| MCL1 | myeloid cell leukemia 1 | 0.0503632 |
| HMGA2 | high mobility group AT-hook 2 | 0.0492209 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0491664 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0461232 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0460097 |
| TPM3 | tropomyosin 3 | 0.0458873 |
| GRB10 | growth factor receptor-bound protein 10 | 0.044998 |
| RCOR1 | REST corepressor 1 | 0.044204 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0437408 |
| RPL3 | ribosomal protein L3 | 0.0431412 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0423761 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0420058 |
| RPS12 | ribosomal protein S12 | 0.0417207 |
| LAMC2 | laminin, gamma 2 | 0.0417163 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0396877 |
| INTS6 | integrator complex subunit 6 | 0.0388627 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0381324 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0381065 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0379647 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0377195 |
| PLS3 | plastin 3 | 0.0366222 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0365733 |
| MYO10 | myosin X | 0.0364817 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0360825 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0360002 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0356778 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0356365 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0353711 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0352862 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0349269 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.034826 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0345933 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0344631 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342632 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0340927 |
| DIAPH1 | diaphanous-related formin 1 | 0.0336725 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0335539 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0333255 |
| INSIG2 | insulin induced gene 2 | 0.033163 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0328514 |
| HDGF | hepatoma-derived growth factor | 0.0328184 |
| FRMD6 | FERM domain containing 6 | 0.0322622 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0322232 |
| RNF145 | ring finger protein 145 | 0.0321333 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0320385 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315363 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0314865 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.031366 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0311356 |
| DHFR | dihydrofolate reductase | 0.0309201 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0308772 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0306394 |
| SLK | STE20-like kinase | 0.0305505 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0300497 |
| SET | SET nuclear proto-oncogene | 0.0297708 |
| FNIP1 | folliculin interacting protein 1 | 0.0296958 |
| RPS18 | ribosomal protein S18 | 0.0295509 |
| FAM13A | family with sequence similarity 13, member A | 0.0289216 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.028858 |
| FAM120A | family with sequence similarity 120A | 0.0282825 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0278529 |
| CD9 | CD9 molecule | 0.0277504 |
| FMNL2 | formin-like 2 | 0.027502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0271706 |
| VEGFA | vascular endothelial growth factor A | 0.027135 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.027125 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0268425 |
| RNF217 | ring finger protein 217 | 0.0268062 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0265674 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265505 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0265027 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0263246 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0261254 |
| RNF19B | ring finger protein 19B | 0.0259162 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0257029 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0253758 |
| RASAL2 | RAS protein activator like 2 | 0.0253387 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0251565 |
| SETD5 | SET domain containing 5 | 0.0251378 |
| ATP13A3 | ATPase type 13A3 | 0.0251279 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0248794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.230368 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.206194 |
| EMP1 | epithelial membrane protein 1 | -0.0942384 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0911237 |
| CD44 | CD44 molecule (Indian blood group) | -0.0899667 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.087945 |
| OSMR | oncostatin M receptor | -0.0836972 |
| IGF2 | insulin-like growth factor 2 | -0.0818409 |
| FOXO1 | forkhead box O1 | -0.081527 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0786951 |
| FOXP1 | forkhead box P1 | -0.0701585 |
| H1-0 | H1.0 linker histone | -0.0642863 |
| CLU | clusterin | -0.0635717 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0610432 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0600616 |
| LDHA | lactate dehydrogenase A | -0.0597474 |
| RPS21 | ribosomal protein S21 | -0.0576195 |
| ANXA2 | annexin A2 | -0.0575752 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0556027 |
| FN1 | fibronectin 1 | -0.0547072 |
| NRG1 | neuregulin 1 | -0.0518056 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0517521 |
| HLA-B | major histocompatibility complex, class I, B | -0.0512373 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0503039 |
| PLAT | plasminogen activator, tissue | -0.0487092 |
| AHNAK | AHNAK nucleoprotein | -0.0453038 |
| TMSB10 | thymosin beta 10 | -0.0450269 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0447382 |
| AOPEP | aminopeptidase O (putative) | -0.0444404 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.043229 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0428491 |
| S100A10 | S100 calcium binding protein A10 | -0.0424459 |
| ARF1 | ADP-ribosylation factor 1 | -0.0424061 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.041173 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0395275 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0394129 |
| NDRG1 | N-myc downstream regulated 1 | -0.038982 |
| BCL2L1 | BCL2-like 1 | -0.0386339 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0385141 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0383381 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0383146 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0381001 |
| LMNA | lamin A/C | -0.0364785 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0364748 |
| RPS24 | ribosomal protein S24 | -0.0363345 |
| HM13 | histocompatibility (minor) 13 | -0.0362861 |
| PALLD | palladin, cytoskeletal associated protein | -0.0362654 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0361585 |
| SULF1 | sulfatase 1 | -0.035733 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0354205 |
| DUSP4 | dual specificity phosphatase 4 | -0.0341035 |
| NEK7 | NIMA-related kinase 7 | -0.033958 |
| STC1 | stanniocalcin 1 | -0.0336276 |
| FTL | ferritin, light polypeptide | -0.0335987 |
| RPLP2 | ribosomal protein, large, P2 | -0.0332731 |
| GNAS | GNAS complex locus | -0.0327827 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.032429 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0320925 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0319415 |
| LOC112694756 | uncharaterized LOC112694756 | -0.031179 |
| CAVIN1 | caveolae associated protein 1 | -0.0310347 |
| IER3 | immediate early response 3 | -0.0308324 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0307876 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0307747 |
| RPL34 | ribosomal protein L34 | -0.030537 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0301363 |
| TXNRD1 | thioredoxin reductase 1 | -0.030132 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0299455 |
| MECOM | MDS1 and EVI1 complex locus | -0.0298888 |
| RRBP1 | ribosome binding protein 1 | -0.029801 |
| TMEM263 | transmembrane protein 263 | -0.0297718 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0296961 |
| IRF1 | interferon regulatory factor 1 | -0.0295635 |
| CD99 | CD99 molecule | -0.0287843 |
| EHF | ets homologous factor | -0.0287822 |
| SDCBP | syndecan binding protein (syntenin) | -0.02877 |
| ZNF217 | zinc finger protein 217 | -0.0283213 |
| ITGA6 | integrin, alpha 6 | -0.0280593 |
| S100A9 | S100 calcium binding protein A9 | -0.0279312 |
| RPS23 | ribosomal protein S23 | -0.0275711 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0275105 |
| MT2A | metallothionein 2A | -0.0272883 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0269785 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.026844 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0267742 |
| ADIRF | adipogenesis regulatory factor | -0.0267667 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0265293 |
| MKI67 | marker of proliferation Ki-67 | -0.0264091 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0262814 |
| CALU | calumenin | -0.0262625 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0262276 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0261934 |
| RPS8 | ribosomal protein S8 | -0.0261412 |
| LDLR | low density lipoprotein receptor | -0.0259151 |
| RIN2 | Ras and Rab interactor 2 | -0.0258719 |
| HLA-E | major histocompatibility complex, class I, E | -0.0256459 |
| SYPL1 | synaptophysin-like 1 | -0.0251563 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0247474 |
| RBM39 | RNA binding motif protein 39 | -0.0245199 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0243417 |
