| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.154911 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.151505 |
| LMO7 | LIM domain 7 | 0.0799609 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0577507 |
| EHBP1 | EH domain binding protein 1 | 0.052681 |
| FRMD5 | FERM domain containing 5 | 0.0465329 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0449749 |
| ANXA2 | annexin A2 | 0.0444346 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0426358 |
| MECOM | MDS1 and EVI1 complex locus | 0.0420098 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0415236 |
| SIK3 | SIK family kinase 3 | 0.0392209 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0391415 |
| PTK2 | protein tyrosine kinase 2 | 0.0369552 |
| EMP1 | epithelial membrane protein 1 | 0.0368538 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0356558 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.035413 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0348823 |
| POF1B | premature ovarian failure, 1B | 0.0340769 |
| SHROOM3 | shroom family member 3 | 0.033979 |
| AOPEP | aminopeptidase O (putative) | 0.0338585 |
| CDK6 | cyclin-dependent kinase 6 | 0.0337186 |
| SLK | STE20-like kinase | 0.0337112 |
| MYO1D | myosin ID | 0.0331377 |
| TCF12 | transcription factor 12 | 0.0327111 |
| RUNX1 | runt-related transcription factor 1 | 0.0324584 |
| CAPN8 | calpain 8 | 0.0318961 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0316727 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.031606 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0314563 |
| ITGA6 | integrin, alpha 6 | 0.0309924 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0297205 |
| TMC5 | transmembrane channel-like 5 | 0.0296131 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0294172 |
| MCU | mitochondrial calcium uniporter | 0.0290735 |
| GOLGB1 | golgin B1 | 0.0289045 |
| COBL | cordon-bleu WH2 repeat protein | 0.0284534 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0283606 |
| AHR | aryl hydrocarbon receptor | 0.0283305 |
| SPATA13 | spermatogenesis associated 13 | 0.0275803 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0274835 |
| MED13 | mediator complex subunit 13 | 0.0274295 |
| ASPH | aspartate beta-hydroxylase | 0.0271205 |
| EXOC4 | exocyst complex component 4 | 0.0270839 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0269762 |
| FAT1 | FAT atypical cadherin 1 | 0.0261391 |
| CMIP | c-Maf inducing protein | 0.0258947 |
| SEPTIN9 | septin 9 | 0.0257094 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0256575 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0255283 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0254732 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0254619 |
| H1-0 | H1.0 linker histone | 0.0249281 |
| YAP1 | Yes-associated protein 1 | 0.0248539 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0248297 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0248214 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0247718 |
| KLHL29 | kelch-like family member 29 | 0.0247371 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0247246 |
| MKI67 | marker of proliferation Ki-67 | 0.0242394 |
| PKP4 | plakophilin 4 | 0.0240971 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0238758 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0237926 |
| TXNRD1 | thioredoxin reductase 1 | 0.0237717 |
| PRKCA | protein kinase C, alpha | 0.023477 |
| FAM135A | family with sequence similarity 135, member A | 0.0233162 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0231701 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0229629 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0228438 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0226818 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0226018 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.022536 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0223678 |
| ATP11A | ATPase, class VI, type 11A | 0.0222576 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221922 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0221908 |
| NF1 | neurofibromin 1 | 0.0221143 |
| DENND1A | DENN/MADD domain containing 1A | 0.0219074 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0218914 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0217662 |
| H1-4 | H1.4 linker histone, cluster member | 0.0217476 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0217326 |
| MYO1E | myosin IE | 0.0212736 |
| EXPH5 | exophilin 5 | 0.0211799 |
| GDA | guanine deaminase | 0.0211007 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0206348 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0203524 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0203309 |
| XYLT1 | xylosyltransferase I | 0.020317 |
| ANLN | anillin, actin binding protein | 0.0203126 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0201436 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0196637 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0194739 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0193653 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0193104 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0192938 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0192129 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0191331 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0190992 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0190627 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.131161 |
| TMSB10 | thymosin beta 10 | -0.128313 |
| PTMA | prothymosin, alpha | -0.122919 |
| PCBP2 | poly(rC) binding protein 2 | -0.102604 |
| FTL | ferritin, light polypeptide | -0.0982127 |
| S100A6 | S100 calcium binding protein A6 | -0.097037 |
| PGK1 | phosphoglycerate kinase 1 | -0.0965907 |
| RPL23 | ribosomal protein L23 | -0.0955923 |
| S100A10 | S100 calcium binding protein A10 | -0.0853936 |
| POTEF | POTE ankyrin domain family, member F | -0.0811836 |
| RPL35A | ribosomal protein L35a | -0.0808312 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0796325 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0779209 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0761953 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0734101 |
| HMGA1 | high mobility group AT-hook 1 | -0.0708746 |
| LYZ | lysozyme | -0.0699236 |
| RPL19 | ribosomal protein L19 | -0.0664648 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.066302 |
| CALR | calreticulin | -0.0649087 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0633422 |
| KRT18 | keratin 18, type I | -0.0605484 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0598471 |
| KRT19 | keratin 19, type I | -0.0596052 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0587017 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0582669 |
| RPS6 | ribosomal protein S6 | -0.0577218 |
| HLA-A | major histocompatibility complex, class I, A | -0.0550263 |
| NDRG1 | N-myc downstream regulated 1 | -0.0544571 |
| S100P | S100 calcium binding protein P | -0.0542066 |
| HYOU1 | hypoxia up-regulated 1 | -0.0520907 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.052082 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0517387 |
| B2M | beta-2-microglobulin | -0.0514808 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0509824 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0492434 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0487679 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0474204 |
| RPS19 | ribosomal protein S19 | -0.0470354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0469529 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0467293 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0464845 |
| RPLP1 | ribosomal protein, large, P1 | -0.0464176 |
| ATF5 | activating transcription factor 5 | -0.0446937 |
| RPS3 | ribosomal protein S3 | -0.044678 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0440588 |
| CLDN7 | claudin 7 | -0.0434752 |
| RPS12 | ribosomal protein S12 | -0.0431497 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0423028 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0415795 |
| AHNAK | AHNAK nucleoprotein | -0.0412666 |
| ENO1 | enolase 1, (alpha) | -0.0405541 |
| PKM | pyruvate kinase, muscle | -0.0403715 |
| MUC17 | mucin 17, cell surface associated | -0.0401539 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.039899 |
| PERP | PERP, TP53 apoptosis effector | -0.0387752 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0383974 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.038319 |
| ARCN1 | archain 1 | -0.0381465 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0365299 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0351169 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0349058 |
| RPS18 | ribosomal protein S18 | -0.0346698 |
| SETD5 | SET domain containing 5 | -0.0342613 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0342231 |
| S100A9 | S100 calcium binding protein A9 | -0.0338949 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0338742 |
| EZR | ezrin | -0.0334708 |
| TMSB4X | thymosin beta 4, X-linked | -0.0332555 |
| LIMA1 | LIM domain and actin binding 1 | -0.0331688 |
| CBX3 | chromobox homolog 3 | -0.0328459 |
| KLK10 | kallikrein-related peptidase 10 | -0.0326863 |
| MUC1 | mucin 1, cell surface associated | -0.0326694 |
| JUP | junction plakoglobin | -0.0322083 |
| GNAS | GNAS complex locus | -0.0320296 |
| CLDN4 | claudin 4 | -0.0320126 |
| RPS25 | ribosomal protein S25 | -0.0315513 |
| ACTG1 | actin gamma 1 | -0.0314394 |
| UBC | ubiquitin C | -0.0312236 |
| RPL18 | ribosomal protein L18 | -0.0312125 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0306537 |
| DSPP | dentin sialophosphoprotein | -0.0301876 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0299005 |
| ITGB4 | integrin, beta 4 | -0.0296133 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0295934 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0295735 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0295542 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0286699 |
| PFN1 | profilin 1 | -0.0285671 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.028428 |
| S100A11 | S100 calcium binding protein A11 | -0.0284149 |
| CD9 | CD9 molecule | -0.0284139 |
| GPX2 | glutathione peroxidase 2 | -0.0282564 |
| RPL26 | ribosomal protein L26 | -0.0278976 |
| TPI1 | triosephosphate isomerase 1 | -0.0276114 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0275423 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0274648 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0273186 |
| DEK | DEK proto-oncogene | -0.0272799 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0272598 |
