| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.12951 |
| NPSR1 | neuropeptide S receptor 1 | 0.101779 |
| PTMA | prothymosin, alpha | 0.0850087 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0805914 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0743544 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0721866 |
| FAM13A | family with sequence similarity 13, member A | 0.0690858 |
| NDRG1 | N-myc downstream regulated 1 | 0.0617777 |
| CD47 | CD47 molecule | 0.0603608 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0548979 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0503616 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0498649 |
| PRELID2 | PRELI domain containing 2 | 0.0461939 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0451788 |
| ZNF292 | zinc finger protein 292 | 0.0448153 |
| ASPH | aspartate beta-hydroxylase | 0.0429444 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0428944 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0424694 |
| DSPP | dentin sialophosphoprotein | 0.0409594 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0404816 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0386481 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0365903 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0363296 |
| GOLGA4 | golgin A4 | 0.0359508 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.03494 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0348946 |
| MXD1 | MAX dimerization protein 1 | 0.034408 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0338254 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0334035 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.033114 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0319697 |
| ATXN1 | ataxin 1 | 0.0314762 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0313015 |
| ANLN | anillin, actin binding protein | 0.0312472 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0310972 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0309312 |
| H1-4 | H1.4 linker histone, cluster member | 0.0307098 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0304705 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.030174 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0300831 |
| RPL7A | ribosomal protein L7a | 0.0300163 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0297986 |
| FBXO11 | F-box protein 11 | 0.0296556 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0295068 |
| RNF217 | ring finger protein 217 | 0.0294111 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.02916 |
| HELZ | helicase with zinc finger | 0.0290961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0284166 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0282762 |
| PTEN | phosphatase and tensin homolog | 0.028224 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0281921 |
| GOLGB1 | golgin B1 | 0.0281814 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0280275 |
| SBF2 | SET binding factor 2 | 0.0280174 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0278011 |
| BBX | bobby sox homolog (Drosophila) | 0.0276275 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0268894 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0268728 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0268506 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0262895 |
| TMSB4X | thymosin beta 4, X-linked | 0.0261566 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0261337 |
| EPCAM | epithelial cell adhesion molecule | 0.0259218 |
| DIAPH2 | diaphanous-related formin 2 | 0.0258727 |
| DENND1A | DENN/MADD domain containing 1A | 0.0257925 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0257825 |
| ARFGEF3 | ARFGEF family member 3 | 0.0257761 |
| CENPF | centromere protein F, 350/400kDa | 0.0256472 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0256452 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.025569 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0252999 |
| VEGFA | vascular endothelial growth factor A | 0.0252052 |
| DIAPH3 | diaphanous-related formin 3 | 0.0251903 |
| FNBP1L | formin binding protein 1-like | 0.0249191 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249184 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0248939 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0248631 |
| MKI67 | marker of proliferation Ki-67 | 0.0247894 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0246367 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0246005 |
| RPL14 | ribosomal protein L14 | 0.0242827 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0242052 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0241151 |
| COPA | coatomer protein complex, subunit alpha | 0.0240668 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0239935 |
| ENO1 | enolase 1, (alpha) | 0.0239401 |
| FNIP1 | folliculin interacting protein 1 | 0.0238751 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0237886 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.023719 |
| CLTC | clathrin, heavy chain (Hc) | 0.0236025 |
| FOSL1 | FOS-like antigen 1 | 0.0234648 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0232922 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0232083 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0231337 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0230349 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0228555 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0228403 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0228124 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0227832 |
| VIM | vimentin | 0.0227671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.112188 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0998501 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0950915 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0876819 |
| LMO7 | LIM domain 7 | -0.0658535 |
| HMGA1 | high mobility group AT-hook 1 | -0.0576415 |
| PCBP2 | poly(rC) binding protein 2 | -0.0563082 |
| PIGR | polymeric immunoglobulin receptor | -0.0558788 |
| TMSB10 | thymosin beta 10 | -0.0553021 |
| FTL | ferritin, light polypeptide | -0.0533136 |
| PKM | pyruvate kinase, muscle | -0.0512965 |
| ONECUT3 | one cut homeobox 3 | -0.04938 |
| TNS4 | tensin 4 | -0.0491237 |
| RPS18 | ribosomal protein S18 | -0.0485515 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0469618 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0454408 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0451277 |
| KRT8 | keratin 8, type II | -0.0440321 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.043423 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0421033 |
| AHNAK | AHNAK nucleoprotein | -0.0409667 |
| KRT18 | keratin 18, type I | -0.0405697 |
| RPL3 | ribosomal protein L3 | -0.0405133 |
| RNF43 | ring finger protein 43 | -0.0388618 |
| S100A6 | S100 calcium binding protein A6 | -0.0379091 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0359099 |
| MYO1E | myosin IE | -0.0357533 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0355948 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0351613 |
| ABLIM1 | actin binding LIM protein 1 | -0.0343592 |
| FAT1 | FAT atypical cadherin 1 | -0.0343002 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0333357 |
| S100A14 | S100 calcium binding protein A14 | -0.0329294 |
| RPL19 | ribosomal protein L19 | -0.0329016 |
| ACTN4 | actinin, alpha 4 | -0.0327077 |
| CCND1 | cyclin D1 | -0.0322572 |
| PRSS3 | protease, serine, 3 | -0.0317175 |
| YBX1 | Y box binding protein 1 | -0.030409 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0302842 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0300514 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0299891 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0299255 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0291006 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0284728 |
| PLEC | plectin | -0.0283947 |
| RPL12 | ribosomal protein L12 | -0.0271726 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0270739 |
| CD44 | CD44 molecule (Indian blood group) | -0.0267496 |
| HDLBP | high density lipoprotein binding protein | -0.0266231 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0262767 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0260381 |
| CADPS | Ca++-dependent secretion activator | -0.0257176 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0255169 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0254322 |
| TXNRD1 | thioredoxin reductase 1 | -0.0250204 |
| SON | SON DNA binding protein | -0.0249644 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0249144 |
| SEPTIN9 | septin 9 | -0.0247739 |
| RBM25 | RNA binding motif protein 25 | -0.0241329 |
| RPS2 | ribosomal protein S2 | -0.0240673 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0239721 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0236325 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0235701 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0235412 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0226691 |
| DHFR | dihydrofolate reductase | -0.0226661 |
| ZFP36 | ZFP36 ring finger protein | -0.0226214 |
| RPL31 | ribosomal protein L31 | -0.0226102 |
| LMNA | lamin A/C | -0.0224671 |
| FHL2 | four and a half LIM domains 2 | -0.0223783 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0222594 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0222548 |
| CTBP2 | C-terminal binding protein 2 | -0.0218795 |
| S100A10 | S100 calcium binding protein A10 | -0.021825 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0216624 |
| TRIM2 | tripartite motif containing 2 | -0.0216216 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0215589 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0214115 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0213857 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0212806 |
| RPL34 | ribosomal protein L34 | -0.0209554 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0207978 |
| EGR1 | early growth response 1 | -0.0205575 |
| POTEF | POTE ankyrin domain family, member F | -0.0202851 |
| LDHA | lactate dehydrogenase A | -0.020249 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0199677 |
| ARF1 | ADP-ribosylation factor 1 | -0.0199251 |
| APP | amyloid beta (A4) precursor protein | -0.0198018 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0196718 |
| RAB10 | RAB10, member RAS oncogene family | -0.0195241 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0194312 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.0194111 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0189507 |
| ABHD17C | abhydrolase domain containing 17C | -0.0189447 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0186885 |
| GNAS | GNAS complex locus | -0.0186815 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0185594 |
| HDAC2 | histone deacetylase 2 | -0.0184245 |
| POF1B | premature ovarian failure, 1B | -0.0183633 |
| KRT19 | keratin 19, type I | -0.0183103 |
