| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.255174 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.102827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0994246 |
| TMSB4X | thymosin beta 4, X-linked | 0.0878109 |
| FMNL2 | formin-like 2 | 0.0871649 |
| CANX | calnexin | 0.0826848 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0789222 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0764579 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0735529 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0689433 |
| VIM | vimentin | 0.0675222 |
| DST | dystonin | 0.0660587 |
| SET | SET nuclear proto-oncogene | 0.0655271 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0597847 |
| ENO1 | enolase 1, (alpha) | 0.0554734 |
| EFNA5 | ephrin-A5 | 0.053739 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.053623 |
| MYOF | myoferlin | 0.0501886 |
| RPS12 | ribosomal protein S12 | 0.0499796 |
| RAI1 | retinoic acid induced 1 | 0.049485 |
| PGK1 | phosphoglycerate kinase 1 | 0.0490015 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0487065 |
| EHBP1 | EH domain binding protein 1 | 0.0478322 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0477396 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0470368 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0466592 |
| PLK2 | polo-like kinase 2 | 0.0464212 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0457437 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0447287 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0443717 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0436603 |
| RAD51B | RAD51 paralog B | 0.0435029 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0428327 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0423834 |
| GOLGA4 | golgin A4 | 0.0421735 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0409663 |
| CDK19 | cyclin-dependent kinase 19 | 0.0401176 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0390901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0387512 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0382485 |
| TPR | translocated promoter region, nuclear basket protein | 0.0382037 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.037983 |
| TSC22D1 | TSC22 domain family, member 1 | 0.037713 |
| RPS6 | ribosomal protein S6 | 0.0375346 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0373913 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0373298 |
| CALR | calreticulin | 0.0372314 |
| RPS3 | ribosomal protein S3 | 0.0345258 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.034435 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0343146 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0339997 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0335282 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0333901 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0331644 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0324307 |
| EPHA4 | EPH receptor A4 | 0.0323225 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0322653 |
| APP | amyloid beta (A4) precursor protein | 0.0321446 |
| PCBP2 | poly(rC) binding protein 2 | 0.0320901 |
| MSN | moesin | 0.0319984 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0316495 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0315068 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0307414 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0306524 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0305801 |
| XPO1 | exportin 1 | 0.0305291 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0304927 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0302295 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0298824 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0298467 |
| FNIP1 | folliculin interacting protein 1 | 0.0295528 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0294667 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0292066 |
| TMF1 | TATA element modulatory factor 1 | 0.0289904 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0287474 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0283896 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0282617 |
| SETD5 | SET domain containing 5 | 0.0275659 |
| RBM25 | RNA binding motif protein 25 | 0.0275527 |
| RPL3 | ribosomal protein L3 | 0.0273658 |
| WASF2 | WAS protein family, member 2 | 0.0272137 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0266891 |
| SLK | STE20-like kinase | 0.0266327 |
| HDGF | hepatoma-derived growth factor | 0.0262172 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0262073 |
| TPM3 | tropomyosin 3 | 0.0261986 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0261984 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0261309 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0257154 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0256063 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0255703 |
| FAM13B | family with sequence similarity 13, member B | 0.0253587 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.02518 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0251008 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0250643 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0250024 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0248926 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247283 |
| MOK | MOK protein kinase | 0.0247089 |
| CAPRIN2 | caprin family member 2 | 0.0246776 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.391259 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0937153 |
| TXNRD1 | thioredoxin reductase 1 | -0.0767346 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0687823 |
| MT2A | metallothionein 2A | -0.0684849 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0590556 |
| EGR1 | early growth response 1 | -0.0546499 |
| TMSB10 | thymosin beta 10 | -0.0541451 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0468761 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0421025 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0394553 |
| ACTG1 | actin gamma 1 | -0.0377255 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374874 |
| EMP1 | epithelial membrane protein 1 | -0.0368745 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0362161 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0355212 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0349668 |
| AHNAK | AHNAK nucleoprotein | -0.0315858 |
| SRGN | serglycin | -0.0315294 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0313735 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0305274 |
| RPL35A | ribosomal protein L35a | -0.0299291 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0295142 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0290462 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0287042 |
| HLA-B | major histocompatibility complex, class I, B | -0.0281551 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0275801 |
| MT1E | metallothionein 1E | -0.0270146 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0267136 |
| FTL | ferritin, light polypeptide | -0.0265793 |
| MT1X | metallothionein 1X | -0.0261774 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0253017 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0249581 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0240681 |
| RTN4 | reticulon 4 | -0.0239696 |
| SDC4 | syndecan 4 | -0.0235544 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0227572 |
| FUS | FUS RNA binding protein | -0.0224267 |
| TP63 | tumor protein p63 | -0.0214598 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0213 |
| OSMR | oncostatin M receptor | -0.0207463 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0206672 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0200204 |
| KLF6 | Kruppel-like factor 6 | -0.0197847 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0193619 |
| HMGA1 | high mobility group AT-hook 1 | -0.0192473 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0192344 |
| ARF1 | ADP-ribosylation factor 1 | -0.0191932 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0183336 |
| RPL28 | ribosomal protein L28 | -0.0182776 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0180426 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0178755 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0177987 |
| CUL1 | cullin 1 | -0.0177964 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0177113 |
| H1-0 | H1.0 linker histone | -0.0176432 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0176079 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0175673 |
| ZNF267 | zinc finger protein 267 | -0.0174804 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0173679 |
| ZFX | zinc finger protein, X-linked | -0.0173297 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0170833 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0170526 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0170047 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0169421 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0168947 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0167247 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0166368 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0165501 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0164346 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0164212 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0163359 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0162767 |
| RPL38 | ribosomal protein L38 | -0.0162691 |
| HDLBP | high density lipoprotein binding protein | -0.0162254 |
| ZNF217 | zinc finger protein 217 | -0.0162158 |
| USP12 | ubiquitin specific peptidase 12 | -0.0162136 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0161886 |
| IRF1 | interferon regulatory factor 1 | -0.0157466 |
| JUN | jun proto-oncogene | -0.0156795 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.015595 |
| FBXO11 | F-box protein 11 | -0.0153396 |
| RPL6 | ribosomal protein L6 | -0.0152777 |
| HBP1 | HMG-box transcription factor 1 | -0.0151626 |
| HJURP | Holliday junction recognition protein | -0.0149689 |
| RRBP1 | ribosome binding protein 1 | -0.0146594 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0146268 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0145739 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.014549 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0145228 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0144626 |
| IL6ST | interleukin 6 signal transducer | -0.0144334 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.01435 |
| PLSCR1 | phospholipid scramblase 1 | -0.0143042 |
| NPR2 | natriuretic peptide receptor 2 | -0.0142874 |
| RIGI | RNA sensor RIG-I | -0.0140799 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0140501 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0139614 |
| PRNP | prion protein | -0.0138953 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.013532 |
