| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.0958877 |
| FAM13A | family with sequence similarity 13, member A | 0.0366412 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0292479 |
| ASPH | aspartate beta-hydroxylase | 0.0288909 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0277787 |
| NGLY1 | N-glycanase 1 | 0.0251623 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0245374 |
| FNIP1 | folliculin interacting protein 1 | 0.0234387 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0233631 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0226999 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0222969 |
| LAMC2 | laminin, gamma 2 | 0.0216723 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0213918 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0211477 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0203593 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0199545 |
| PCBP2 | poly(rC) binding protein 2 | 0.0192956 |
| DSPP | dentin sialophosphoprotein | 0.0186255 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0186216 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0185746 |
| SLTM | SAFB-like, transcription modulator | 0.0182729 |
| LMO7 | LIM domain 7 | 0.0177792 |
| ARRDC3 | arrestin domain containing 3 | 0.0176653 |
| MSN | moesin | 0.0176279 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0173951 |
| TOP1 | topoisomerase (DNA) I | 0.0173378 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0171345 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0171281 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.017055 |
| PTMA | prothymosin, alpha | 0.0168203 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0167894 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0166037 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.016261 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0161184 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0150682 |
| ATP13A3 | ATPase type 13A3 | 0.0147971 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0147518 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0144928 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0143766 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0142586 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0140715 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0140577 |
| RNF145 | ring finger protein 145 | 0.0140297 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0140061 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0138001 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0136028 |
| SLMAP | sarcolemma associated protein | 0.0133895 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.013357 |
| UVRAG | UV radiation resistance associated | 0.0133361 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0133034 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.013165 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0131478 |
| RASA2 | RAS p21 protein activator 2 | 0.0131019 |
| PTEN | phosphatase and tensin homolog | 0.01309 |
| GPC6 | glypican 6 | 0.0130619 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0130395 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0128198 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0126206 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0124977 |
| SQSTM1 | sequestosome 1 | 0.0124638 |
| SEPTIN2 | septin 2 | 0.0124326 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0124277 |
| SPAG9 | sperm associated antigen 9 | 0.0123891 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0123839 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0123617 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0122522 |
| CAB39 | calcium binding protein 39 | 0.0121926 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0119746 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0119086 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0116963 |
| YEATS2 | YEATS domain containing 2 | 0.0116815 |
| ZNF292 | zinc finger protein 292 | 0.0116488 |
| TPD52 | tumor protein D52 | 0.0115349 |
| SMAD3 | SMAD family member 3 | 0.0113492 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0113467 |
| HELZ | helicase with zinc finger | 0.0113252 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0112047 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0111826 |
| PGK1 | phosphoglycerate kinase 1 | 0.0111616 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0111395 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.011084 |
| RBM26 | RNA binding motif protein 26 | 0.0110502 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.011029 |
| ANO6 | anoctamin 6 | 0.0110273 |
| MED13L | mediator complex subunit 13-like | 0.0110055 |
| NCKAP1 | NCK-associated protein 1 | 0.0109894 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0109726 |
| USP34 | ubiquitin specific peptidase 34 | 0.0109536 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0109517 |
| MATR3 | matrin 3 | 0.0108178 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0107496 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0106193 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0105654 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0105361 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0104821 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0104552 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.010401 |
| OGA | O-GlcNAcase | 0.0104009 |
| KIAA1217 | KIAA1217 | 0.0103015 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0101437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.363742 |
| MT2A | metallothionein 2A | -0.100555 |
| TMSB10 | thymosin beta 10 | -0.0589644 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0443934 |
| FTL | ferritin, light polypeptide | -0.0424612 |
| EGR1 | early growth response 1 | -0.0361763 |
| RPLP1 | ribosomal protein, large, P1 | -0.0356876 |
| RPL35A | ribosomal protein L35a | -0.0333506 |
| SEC61G | Sec61 gamma subunit | -0.0325573 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0292346 |
| MT1X | metallothionein 1X | -0.0253759 |
| S100A10 | S100 calcium binding protein A10 | -0.0230156 |
| RPS24 | ribosomal protein S24 | -0.0224285 |
| ACTG1 | actin gamma 1 | -0.0224129 |
| IER3 | immediate early response 3 | -0.0219 |
| PKM | pyruvate kinase, muscle | -0.0214889 |
| RPS8 | ribosomal protein S8 | -0.0211863 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0202995 |
| RPS25 | ribosomal protein S25 | -0.0197607 |
| RPL34 | ribosomal protein L34 | -0.0194809 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0194077 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0184515 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0184474 |
| H1-0 | H1.0 linker histone | -0.0168453 |
| RPL8 | ribosomal protein L8 | -0.0166043 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0165344 |
| RPL31 | ribosomal protein L31 | -0.0159319 |
| RPS29 | ribosomal protein S29 | -0.0158272 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0157987 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0156986 |
| EMP1 | epithelial membrane protein 1 | -0.0155445 |
| RPL12 | ribosomal protein L12 | -0.0153616 |
| RPL19 | ribosomal protein L19 | -0.0152976 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0152013 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0149659 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0147646 |
| RPS23 | ribosomal protein S23 | -0.0147546 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0143861 |
| RPS21 | ribosomal protein S21 | -0.0143056 |
| RPS3 | ribosomal protein S3 | -0.0141336 |
| TXNRD1 | thioredoxin reductase 1 | -0.0140744 |
| CST3 | cystatin C | -0.0139569 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0137932 |
| RPS19 | ribosomal protein S19 | -0.0136602 |
| FUS | FUS RNA binding protein | -0.0132984 |
| S100A9 | S100 calcium binding protein A9 | -0.0132024 |
| HLA-B | major histocompatibility complex, class I, B | -0.0130629 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0130195 |
| RPL23 | ribosomal protein L23 | -0.0129491 |
| HDLBP | high density lipoprotein binding protein | -0.0128368 |
| S100A11 | S100 calcium binding protein A11 | -0.0126015 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0125412 |
| GRAMD1B | GRAM domain containing 1B | -0.0125211 |
| S100P | S100 calcium binding protein P | -0.0125025 |
| NDRG1 | N-myc downstream regulated 1 | -0.0124462 |
| RPL37A | ribosomal protein L37a | -0.0123658 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0119547 |
| MORF4L2 | mortality factor 4 like 2 | -0.0117985 |
| STC1 | stanniocalcin 1 | -0.0117947 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0117688 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0117527 |
| RPLP2 | ribosomal protein, large, P2 | -0.0115915 |
| RACK1 | receptor for activated C kinase 1 | -0.0115625 |
| LDHA | lactate dehydrogenase A | -0.0114262 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0114109 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.011391 |
| NABP1 | nucleic acid binding protein 1 | -0.0113305 |
| RPL11 | ribosomal protein L11 | -0.0112725 |
| GUK1 | guanylate kinase 1 | -0.0110343 |
| RPL30 | ribosomal protein L30 | -0.01097 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0108471 |
| AREG | amphiregulin | -0.0108378 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0106678 |
| RPS11 | ribosomal protein S11 | -0.0105204 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.0105105 |
| RPS13 | ribosomal protein S13 | -0.0104633 |
| RPS15 | ribosomal protein S15 | -0.0103746 |
| RPL38 | ribosomal protein L38 | -0.0102541 |
| INTS6 | integrator complex subunit 6 | -0.0102445 |
| GM2A | GM2 ganglioside activator | -0.0101924 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0100846 |
| RPL28 | ribosomal protein L28 | -0.00977381 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00968582 |
| RPS14 | ribosomal protein S14 | -0.00964385 |
| RPL36 | ribosomal protein L36 | -0.00957739 |
| ARF1 | ADP-ribosylation factor 1 | -0.00956563 |
| ATF4 | activating transcription factor 4 | -0.00952192 |
| RPS16 | ribosomal protein S16 | -0.00946822 |
| RPS6 | ribosomal protein S6 | -0.00938719 |
| CSTB | cystatin B (stefin B) | -0.00902917 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.00894269 |
| TPI1 | triosephosphate isomerase 1 | -0.00892132 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00877058 |
| AGR2 | anterior gradient 2 | -0.00871366 |
| RPS27 | ribosomal protein S27 | -0.00868045 |
| RPL32 | ribosomal protein L32 | -0.00863824 |
| HMGA1 | high mobility group AT-hook 1 | -0.00862152 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.00825317 |
| RPLP0 | ribosomal protein, large, P0 | -0.00820111 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00805796 |
