| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Plicamycin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.184725 |
| PCBP2 | poly(rC) binding protein 2 | 0.144672 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.133977 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.105392 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103065 |
| GOLGA4 | golgin A4 | 0.0972913 |
| PTMA | prothymosin, alpha | 0.0838552 |
| FAM13A | family with sequence similarity 13, member A | 0.0833361 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0650542 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0594646 |
| SMAD3 | SMAD family member 3 | 0.0593582 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0571575 |
| OGA | O-GlcNAcase | 0.0555942 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0541267 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.053875 |
| CANX | calnexin | 0.0529629 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.052613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0515634 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0501122 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0477572 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0470569 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0459814 |
| NGLY1 | N-glycanase 1 | 0.0457773 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0423635 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0411311 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0410399 |
| SPAG9 | sperm associated antigen 9 | 0.0402822 |
| RBM39 | RNA binding motif protein 39 | 0.0397699 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0394992 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0388313 |
| ENO1 | enolase 1, (alpha) | 0.0382905 |
| APP | amyloid beta (A4) precursor protein | 0.0380692 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0376343 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0374353 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0367724 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0359315 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0348257 |
| HELZ | helicase with zinc finger | 0.0345525 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0343719 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0340903 |
| RIOK3 | RIO kinase 3 | 0.0340603 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0339083 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0338284 |
| VIM | vimentin | 0.0331543 |
| XPO1 | exportin 1 | 0.0325551 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0325125 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0324988 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0324563 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0324308 |
| RPS12 | ribosomal protein S12 | 0.0323809 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0322843 |
| ATP13A3 | ATPase type 13A3 | 0.0318808 |
| MT2A | metallothionein 2A | 0.0314046 |
| USP3 | ubiquitin specific peptidase 3 | 0.0313649 |
| MYOF | myoferlin | 0.0307407 |
| ZNF292 | zinc finger protein 292 | 0.0306931 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0306406 |
| ANXA1 | annexin A1 | 0.0305554 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0305021 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0304532 |
| SRP54 | signal recognition particle 54kDa | 0.0303996 |
| CALR | calreticulin | 0.0302952 |
| TPR | translocated promoter region, nuclear basket protein | 0.0302303 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0301851 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0299235 |
| WDR45B | WD repeat domain 45B | 0.0298756 |
| RNF145 | ring finger protein 145 | 0.0298529 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0297311 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0296514 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0295678 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0292576 |
| MATR3 | matrin 3 | 0.0288089 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0286921 |
| RPLP0 | ribosomal protein, large, P0 | 0.0286573 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0283838 |
| SETD5 | SET domain containing 5 | 0.0282488 |
| SUCO | SUN domain containing ossification factor | 0.0281611 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0274584 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0272804 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.026798 |
| COG5 | component of oligomeric golgi complex 5 | 0.0267858 |
| FLNB | filamin B, beta | 0.0264396 |
| RUNX1 | runt-related transcription factor 1 | 0.0264163 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0262889 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0262791 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0262786 |
| SEPTIN2 | septin 2 | 0.0262248 |
| SBF2 | SET binding factor 2 | 0.0260537 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0260155 |
| YBX1 | Y box binding protein 1 | 0.0258803 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0257618 |
| PRELID2 | PRELI domain containing 2 | 0.0254416 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0251447 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250663 |
| USP37 | ubiquitin specific peptidase 37 | 0.0250639 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0249969 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0247933 |
| SET | SET nuclear proto-oncogene | 0.0246608 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0244834 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0244183 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.137297 |
| FN1 | fibronectin 1 | -0.100036 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0979688 |
| GLCCI1 | glucocorticoid induced 1 | -0.0967861 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0966147 |
| NRG1 | neuregulin 1 | -0.0944705 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0860036 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0846401 |
| CDH13 | cadherin 13 | -0.0806171 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0799503 |
| HMGA2 | high mobility group AT-hook 2 | -0.0780459 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0668694 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0655037 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.065465 |
| CD44 | CD44 molecule (Indian blood group) | -0.0594641 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0592181 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0557734 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0547165 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.049555 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0495188 |
| NRP1 | neuropilin 1 | -0.0481765 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0480292 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0477533 |
| LOX | lysyl oxidase | -0.0475825 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0472346 |
| OSMR | oncostatin M receptor | -0.0466338 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0454824 |
| CLMP | CXADR-like membrane protein | -0.0439346 |
| MTSS1 | metastasis suppressor 1 | -0.0421152 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0415477 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0397784 |
| NTN4 | netrin 4 | -0.0395812 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0391544 |
| EGR1 | early growth response 1 | -0.0387157 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0384931 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0382445 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0373552 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0368401 |
| GLIS3 | GLIS family zinc finger 3 | -0.035798 |
| ANKRD28 | ankyrin repeat domain 28 | -0.035158 |
| RAI14 | retinoic acid induced 14 | -0.0351491 |
| EFNA5 | ephrin-A5 | -0.0332666 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0323534 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0320329 |
| IFI44L | interferon-induced protein 44-like | -0.0315833 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0308168 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0305202 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0303161 |
| GPC6 | glypican 6 | -0.0298423 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0298232 |
| TMSB10 | thymosin beta 10 | -0.0294591 |
| RASAL2 | RAS protein activator like 2 | -0.0293351 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0292369 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0288746 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0285301 |
| ZNF804A | zinc finger protein 804A | -0.0285251 |
| WLS | wntless Wnt ligand secretion mediator | -0.028339 |
| AADAC | arylacetamide deacetylase | -0.0274707 |
| CDK14 | cyclin-dependent kinase 14 | -0.0270758 |
| SYT1 | synaptotagmin I | -0.0267825 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0266382 |
| PRRX1 | paired related homeobox 1 | -0.0264076 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0260729 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0258623 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0256247 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0252231 |
| RNF213 | ring finger protein 213 | -0.0252096 |
| CUX1 | cut-like homeobox 1 | -0.0249304 |
| DST | dystonin | -0.0248959 |
| DIAPH2 | diaphanous-related formin 2 | -0.0246755 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0245979 |
| BMERB1 | bMERB domain containing 1 | -0.0245849 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0241613 |
| FBN1 | fibrillin 1 | -0.0240792 |
| NAV1 | neuron navigator 1 | -0.0239482 |
| MX2 | MX dynamin-like GTPase 2 | -0.0238265 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0237824 |
| ATG7 | autophagy related 7 | -0.0236187 |
| MECOM | MDS1 and EVI1 complex locus | -0.0235629 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0235442 |
| KYNU | kynureninase | -0.0235325 |
| RAD51B | RAD51 paralog B | -0.0231931 |
| ANXA10 | annexin A10 | -0.0227938 |
| SVIL | supervillin | -0.0223933 |
| VRK2 | vaccinia related kinase 2 | -0.0223087 |
| ETV6 | ets variant 6 | -0.0222681 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0220265 |
| IL1B | interleukin 1, beta | -0.0219553 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0217545 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0216071 |
| STC1 | stanniocalcin 1 | -0.0213487 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0213067 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0210515 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0209771 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0209256 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0209077 |
| CLIC4 | chloride intracellular channel 4 | -0.0206686 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0204462 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0201825 |
| DNER | delta/notch-like EGF repeat containing | -0.0201655 |
