| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.14015 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.112439 |
| RAD51B | RAD51 paralog B | 0.0875298 |
| PCBP2 | poly(rC) binding protein 2 | 0.0789529 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0684347 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0678748 |
| MCL1 | myeloid cell leukemia 1 | 0.0583573 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0527357 |
| HMGA2 | high mobility group AT-hook 2 | 0.0502717 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0489325 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0484527 |
| SMAD3 | SMAD family member 3 | 0.0478637 |
| VIM | vimentin | 0.0470224 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0451446 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0443526 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0440354 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0438508 |
| FMNL2 | formin-like 2 | 0.042322 |
| TPM3 | tropomyosin 3 | 0.0417588 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0395755 |
| PDE10A | phosphodiesterase 10A | 0.0391534 |
| ATXN1 | ataxin 1 | 0.0390745 |
| PTMA | prothymosin, alpha | 0.0341185 |
| GRAMD1B | GRAM domain containing 1B | 0.0313795 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030603 |
| AEBP2 | AE binding protein 2 | 0.0302847 |
| WWOX | WW domain containing oxidoreductase | 0.0302507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0289843 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.028059 |
| FNDC3B | fibronectin type III domain containing 3B | 0.027979 |
| EGFR | epidermal growth factor receptor | 0.0278671 |
| RNF213 | ring finger protein 213 | 0.02743 |
| PRELID2 | PRELI domain containing 2 | 0.0261043 |
| RYR3 | ryanodine receptor 3 | 0.0259714 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0252489 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.025213 |
| LOXL2 | lysyl oxidase-like 2 | 0.0248795 |
| DENND1A | DENN/MADD domain containing 1A | 0.0245225 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0239503 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0237601 |
| CEP250 | centrosomal protein 250kDa | 0.0232347 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0227108 |
| HDGF | hepatoma-derived growth factor | 0.0226092 |
| EXOC4 | exocyst complex component 4 | 0.0221157 |
| RPS18 | ribosomal protein S18 | 0.0209931 |
| DIAPH2 | diaphanous-related formin 2 | 0.0206146 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.020547 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0202887 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0201363 |
| RPL3 | ribosomal protein L3 | 0.0199745 |
| HDAC4 | histone deacetylase 4 | 0.0194737 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.019228 |
| EPAS1 | endothelial PAS domain protein 1 | 0.019025 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0186995 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0184441 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0181712 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0179052 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0178878 |
| SMIM44 | small integral membrane protein 44 | 0.0177239 |
| COPA | coatomer protein complex, subunit alpha | 0.0176123 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0175196 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0171153 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.017088 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0170762 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0170293 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0169137 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.01673 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0166549 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0165394 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0164206 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0163781 |
| PTK2 | protein tyrosine kinase 2 | 0.0163248 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0163203 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0162634 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0160177 |
| PFKP | phosphofructokinase, platelet | 0.0158702 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0156944 |
| R3HDM2 | R3H domain containing 2 | 0.0155408 |
| POTEF | POTE ankyrin domain family, member F | 0.0151036 |
| MSI2 | musashi RNA-binding protein 2 | 0.0150652 |
| TPM2 | tropomyosin 2 (beta) | 0.0149539 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0148879 |
| RPS4X | ribosomal protein S4, X-linked | 0.0148876 |
| CUX1 | cut-like homeobox 1 | 0.0148487 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0148376 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0147645 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0147355 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0147348 |
| PHF14 | PHD finger protein 14 | 0.0146454 |
| TMEM14B | transmembrane protein 14B | 0.0145941 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0145524 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0145073 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.014442 |
| PRKCE | protein kinase C, epsilon | 0.0140909 |
| BNC2 | basonuclin 2 | 0.0138453 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0138226 |
| ETV6 | ets variant 6 | 0.0138182 |
| DOCK5 | dedicator of cytokinesis 5 | 0.01381 |
| RBM25 | RNA binding motif protein 25 | 0.0137548 |
| FDPS | farnesyl diphosphate synthase | 0.0136978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.235135 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211222 |
| TXNRD1 | thioredoxin reductase 1 | -0.139925 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0762311 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0661686 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0636327 |
| RTN4 | reticulon 4 | -0.0560173 |
| MKI67 | marker of proliferation Ki-67 | -0.0435347 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0434022 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0432081 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.04292 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0421292 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0409919 |
| CLTC | clathrin, heavy chain (Hc) | -0.0406252 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0405882 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0402523 |
| PHIP | pleckstrin homology domain interacting protein | -0.0379633 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0362909 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0354669 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0346055 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0339166 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0336284 |
| YBX3 | Y box binding protein 3 | -0.0319087 |
| RPS2 | ribosomal protein S2 | -0.0300412 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0300157 |
| KIF5B | kinesin family member 5B | -0.0299835 |
| MYL12B | myosin, light chain 12B, regulatory | -0.029943 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0297751 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.029354 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0292189 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.028816 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0283443 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0282022 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0277596 |
| RPS15 | ribosomal protein S15 | -0.0277549 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0277346 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0271641 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0268532 |
| RPL38 | ribosomal protein L38 | -0.0268289 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266993 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0264699 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0263611 |
| FBXO11 | F-box protein 11 | -0.0254627 |
| MTPN | myotrophin | -0.0250399 |
| GOLT1B | golgi transport 1B | -0.0249198 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0248985 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.024164 |
| RAB10 | RAB10, member RAS oncogene family | -0.024105 |
| RPL12 | ribosomal protein L12 | -0.0240555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.023939 |
| ZFR | zinc finger RNA binding protein | -0.0239026 |
| GPHN | gephyrin | -0.0238674 |
| IGF2 | insulin-like growth factor 2 | -0.0237019 |
| FUS | FUS RNA binding protein | -0.0235801 |
| RPS21 | ribosomal protein S21 | -0.0234709 |
| OGA | O-GlcNAcase | -0.0233835 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0233382 |
| SPAG9 | sperm associated antigen 9 | -0.0233381 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.023257 |
| CCND2 | cyclin D2 | -0.0231721 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.022753 |
| BRD2 | bromodomain containing 2 | -0.0227257 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0222985 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0219075 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0218602 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0217802 |
| WBP11 | WW domain binding protein 11 | -0.021433 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0213344 |
| H3-3B | H3.3 histone B | -0.0213176 |
| XPO1 | exportin 1 | -0.0212506 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0211451 |
| RECQL | RecQ helicase-like | -0.0211232 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0211038 |
| SRP72 | signal recognition particle 72kDa | -0.0210885 |
| SRPK1 | SRSF protein kinase 1 | -0.0210194 |
| TWF1 | twinfilin actin binding protein 1 | -0.0210139 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0207844 |
| PLCB4 | phospholipase C, beta 4 | -0.0207315 |
| ACTG1 | actin gamma 1 | -0.0206679 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0206353 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0206256 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0206129 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0205406 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0204402 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0203755 |
| RPS29 | ribosomal protein S29 | -0.0200215 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0199978 |
| SEPTIN7 | septin 7 | -0.0196664 |
| RPLP1 | ribosomal protein, large, P1 | -0.019658 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0196392 |
| STK4 | serine/threonine kinase 4 | -0.0196207 |
| CUL4B | cullin 4B | -0.0194263 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0193859 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0192626 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0191827 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0191512 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0190374 |
| WDR45B | WD repeat domain 45B | -0.0189415 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0188816 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0187003 |
