| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Plicamycin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0940794 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0919034 |
| MSN | moesin | 0.0661788 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0640287 |
| TMSB4X | thymosin beta 4, X-linked | 0.0610464 |
| VEGFA | vascular endothelial growth factor A | 0.0543642 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0454634 |
| RPS12 | ribosomal protein S12 | 0.043171 |
| PGK1 | phosphoglycerate kinase 1 | 0.0401221 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0375257 |
| RPLP0 | ribosomal protein, large, P0 | 0.0363374 |
| PCBP2 | poly(rC) binding protein 2 | 0.0359225 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348532 |
| RNF145 | ring finger protein 145 | 0.0342037 |
| DSPP | dentin sialophosphoprotein | 0.0319608 |
| RPL3 | ribosomal protein L3 | 0.0308623 |
| RPS18 | ribosomal protein S18 | 0.0306465 |
| FAM13A | family with sequence similarity 13, member A | 0.0283363 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0268316 |
| TPM3 | tropomyosin 3 | 0.0254658 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0251873 |
| KRT18 | keratin 18, type I | 0.0249773 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0249341 |
| SQSTM1 | sequestosome 1 | 0.0245687 |
| RAI14 | retinoic acid induced 14 | 0.0237848 |
| TMF1 | TATA element modulatory factor 1 | 0.0237235 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0235121 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0224337 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219074 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0219053 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0200863 |
| HMGA1 | high mobility group AT-hook 1 | 0.0199971 |
| FOSL1 | FOS-like antigen 1 | 0.0193713 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0192742 |
| GOLGA4 | golgin A4 | 0.0190251 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0187592 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0185666 |
| CBX3 | chromobox homolog 3 | 0.0181326 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.018121 |
| SET | SET nuclear proto-oncogene | 0.0180768 |
| HDGF | hepatoma-derived growth factor | 0.0178805 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0171923 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0168037 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0165141 |
| RPL7 | ribosomal protein L7 | 0.0163018 |
| CALR | calreticulin | 0.0161799 |
| CTSA | cathepsin A | 0.0160883 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0160453 |
| CANX | calnexin | 0.0158016 |
| CTBP2 | C-terminal binding protein 2 | 0.0157288 |
| MATR3 | matrin 3 | 0.015588 |
| CCNL1 | cyclin L1 | 0.0154573 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0154228 |
| ADM | adrenomedullin | 0.01504 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0150341 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0147505 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.014703 |
| HMGB2 | high mobility group box 2 | 0.0145775 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0145246 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0144402 |
| CCNG2 | cyclin G2 | 0.0143744 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0142796 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.014184 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0140531 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0140245 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0137884 |
| TOP1 | topoisomerase (DNA) I | 0.0137169 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0134526 |
| DSTN | destrin (actin depolymerizing factor) | 0.0133405 |
| HELZ | helicase with zinc finger | 0.0131257 |
| CNN3 | calponin 3, acidic | 0.0130834 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0129798 |
| RANBP1 | RAN binding protein 1 | 0.0128577 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0124746 |
| PDS5A | PDS5 cohesin associated factor A | 0.0124662 |
| FDPS | farnesyl diphosphate synthase | 0.0124501 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0123814 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0123752 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0122483 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0121777 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0121758 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0121328 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0120829 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0119934 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0118818 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0118502 |
| MCL1 | myeloid cell leukemia 1 | 0.0117951 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0117808 |
| RPS7 | ribosomal protein S7 | 0.0117651 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0116865 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0116673 |
| RPS17 | ribosomal protein S17 | 0.0115055 |
| GPX4 | glutathione peroxidase 4 | 0.0114816 |
| CCNY | cyclin Y | 0.0114521 |
| RPL37A | ribosomal protein L37a | 0.0112807 |
| NUP58 | nucleoporin 58 | 0.011137 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0110639 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.011041 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.011033 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0109763 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.425562 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.231179 |
| FN1 | fibronectin 1 | -0.22183 |
| UBC | ubiquitin C | -0.207326 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.162415 |
| ACTG1 | actin gamma 1 | -0.110314 |
| TMSB10 | thymosin beta 10 | -0.100938 |
| ASPH | aspartate beta-hydroxylase | -0.0877968 |
| FTL | ferritin, light polypeptide | -0.0830239 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0698141 |
| ANXA2 | annexin A2 | -0.0690566 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0661594 |
| AHNAK | AHNAK nucleoprotein | -0.0659808 |
| NDRG1 | N-myc downstream regulated 1 | -0.0648201 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0583016 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0572235 |
| LMO7 | LIM domain 7 | -0.0567488 |
| RPL23 | ribosomal protein L23 | -0.0524477 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0503353 |
| PTK2 | protein tyrosine kinase 2 | -0.0503112 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0478308 |
| RPL8 | ribosomal protein L8 | -0.0467275 |
| RPS27A | ribosomal protein S27a | -0.0441837 |
| SDC4 | syndecan 4 | -0.0433293 |
| TMEM263 | transmembrane protein 263 | -0.0428261 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0419114 |
| DSG2 | desmoglein 2 | -0.0416166 |
| RPL34 | ribosomal protein L34 | -0.0415505 |
| TXNRD1 | thioredoxin reductase 1 | -0.0412059 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0411661 |
| RHOA | ras homolog family member A | -0.0405455 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.040024 |
| KRT7 | keratin 7, type II | -0.0389471 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0382024 |
| CTSB | cathepsin B | -0.0373337 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0372485 |
| LAMC2 | laminin, gamma 2 | -0.0371161 |
| CCNI | cyclin I | -0.0357043 |
| ERBIN | erbb2 interacting protein | -0.0355809 |
| CALU | calumenin | -0.0352702 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0347553 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0346535 |
| EPCAM | epithelial cell adhesion molecule | -0.0345993 |
| PARD3 | par-3 family cell polarity regulator | -0.0344282 |
| RPL32 | ribosomal protein L32 | -0.0343256 |
| EMP1 | epithelial membrane protein 1 | -0.0338821 |
| CD44 | CD44 molecule (Indian blood group) | -0.0326299 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0324694 |
| MAP4 | microtubule-associated protein 4 | -0.0322796 |
| VGLL3 | vestigial-like family member 3 | -0.0322392 |
| SGMS2 | sphingomyelin synthase 2 | -0.0320465 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0313447 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0311239 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0305418 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0299143 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.029695 |
| S100A10 | S100 calcium binding protein A10 | -0.029667 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0294249 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0294068 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0293476 |
| RYBP | RING1 and YY1 binding protein | -0.0288169 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0285902 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.028262 |
| CD2AP | CD2-associated protein | -0.027911 |
| TXNIP | thioredoxin interacting protein | -0.0278089 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0276071 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.027029 |
| LAMB3 | laminin, beta 3 | -0.0269944 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0268383 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026768 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0267524 |
| OSMR | oncostatin M receptor | -0.0266532 |
| ARF1 | ADP-ribosylation factor 1 | -0.0262904 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0262844 |
| KRT8 | keratin 8, type II | -0.0262619 |
| F11R | F11 receptor | -0.025658 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0254045 |
| LDHA | lactate dehydrogenase A | -0.0251068 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0249122 |
| IL6ST | interleukin 6 signal transducer | -0.0249114 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0248814 |
| JUN | jun proto-oncogene | -0.0245436 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0245405 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.024382 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0242748 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0238958 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0237928 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0237467 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0236724 |
| KLF6 | Kruppel-like factor 6 | -0.0234455 |
| MEF2A | myocyte enhancer factor 2A | -0.0233979 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0233096 |
| RPS15 | ribosomal protein S15 | -0.0232814 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.023157 |
| TFG | TRK-fused gene | -0.0230913 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0230694 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0228993 |
| SVIL | supervillin | -0.0228883 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0228305 |
| FAM3C | family with sequence similarity 3, member C | -0.0228187 |
