| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0896972 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0884415 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0735232 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0580023 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0576682 |
| NEK7 | NIMA-related kinase 7 | 0.0530003 |
| ASPH | aspartate beta-hydroxylase | 0.0471368 |
| RTN4 | reticulon 4 | 0.0431352 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0397657 |
| PTMA | prothymosin, alpha | 0.0393874 |
| TXNRD1 | thioredoxin reductase 1 | 0.0389664 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0383758 |
| OGA | O-GlcNAcase | 0.0383532 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0356937 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0347077 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0335378 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0330107 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0316774 |
| PLCB4 | phospholipase C, beta 4 | 0.0315793 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0309431 |
| ENAH | enabled homolog (Drosophila) | 0.0305923 |
| MATR3 | matrin 3 | 0.029874 |
| SPAG9 | sperm associated antigen 9 | 0.0293133 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0289313 |
| GOLGA4 | golgin A4 | 0.0285887 |
| TNPO1 | transportin 1 | 0.0284345 |
| ZNF292 | zinc finger protein 292 | 0.0283261 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0282386 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0277673 |
| CENPF | centromere protein F, 350/400kDa | 0.0275215 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0272814 |
| MSN | moesin | 0.0271146 |
| CANX | calnexin | 0.0266925 |
| WDR43 | WD repeat domain 43 | 0.0258904 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258785 |
| GRAMD1B | GRAM domain containing 1B | 0.0258001 |
| PTEN | phosphatase and tensin homolog | 0.0249991 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0249596 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0248477 |
| RNF145 | ring finger protein 145 | 0.0246073 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0243923 |
| SRPK2 | SRSF protein kinase 2 | 0.0240945 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0240164 |
| RBM39 | RNA binding motif protein 39 | 0.0238016 |
| CDC73 | cell division cycle 73 | 0.0235943 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0233793 |
| NCKAP1 | NCK-associated protein 1 | 0.0232823 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0232157 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0232065 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0231406 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0230633 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0229207 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.02274 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0225255 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0224123 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.022357 |
| MYOF | myoferlin | 0.0222839 |
| WDR26 | WD repeat domain 26 | 0.0222227 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0219413 |
| RUNX1 | runt-related transcription factor 1 | 0.0218661 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0217756 |
| ECT2 | epithelial cell transforming 2 | 0.021705 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0213724 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0211426 |
| FLNB | filamin B, beta | 0.021124 |
| FAM13A | family with sequence similarity 13, member A | 0.0211031 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0210858 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0210854 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0210847 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0209792 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0209333 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.020849 |
| RAI1 | retinoic acid induced 1 | 0.0207111 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.020633 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0205882 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0205037 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0203125 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0203065 |
| RBM25 | RNA binding motif protein 25 | 0.0203037 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0202522 |
| XPO1 | exportin 1 | 0.0202055 |
| NUP58 | nucleoporin 58 | 0.0201867 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0201766 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0201719 |
| NGLY1 | N-glycanase 1 | 0.0198737 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0198692 |
| ATP13A3 | ATPase type 13A3 | 0.0196954 |
| OLA1 | Obg-like ATPase 1 | 0.0196167 |
| USP3 | ubiquitin specific peptidase 3 | 0.0193928 |
| GDA | guanine deaminase | 0.0192029 |
| COG5 | component of oligomeric golgi complex 5 | 0.0191984 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0191983 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0189365 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.018902 |
| PHIP | pleckstrin homology domain interacting protein | 0.0186636 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0184206 |
| MKI67 | marker of proliferation Ki-67 | 0.0184187 |
| CTSC | cathepsin C | 0.0181653 |
| NF1 | neurofibromin 1 | 0.0181557 |
| HELZ | helicase with zinc finger | 0.0181458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.274148 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.217583 |
| FN1 | fibronectin 1 | -0.197048 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138598 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0858147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0830033 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0817202 |
| PDE10A | phosphodiesterase 10A | -0.078634 |
| CDH13 | cadherin 13 | -0.0757106 |
| VIM | vimentin | -0.0731024 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0728718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0635964 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0601193 |
| COL5A2 | collagen, type V, alpha 2 | -0.0600126 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0565533 |
| FTL | ferritin, light polypeptide | -0.0544657 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0505336 |
| RPS6 | ribosomal protein S6 | -0.0488621 |
| RPS8 | ribosomal protein S8 | -0.0448288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0446842 |
| LSAMP | limbic system-associated membrane protein | -0.0425358 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0419086 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0418506 |
| RPLP1 | ribosomal protein, large, P1 | -0.0411738 |
| HLA-A | major histocompatibility complex, class I, A | -0.0394948 |
| TMSB10 | thymosin beta 10 | -0.0392791 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0392674 |
| RPL35A | ribosomal protein L35a | -0.0391764 |
| HLA-B | major histocompatibility complex, class I, B | -0.0385048 |
| AUTS2 | autism susceptibility candidate 2 | -0.0376526 |
| RPL31 | ribosomal protein L31 | -0.0361288 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0349746 |
| RPL37A | ribosomal protein L37a | -0.0344528 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0344488 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0333647 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0321483 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0318188 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0315998 |
| TBXT | T-box transcription factor T | -0.0312755 |
| CTSL | cathepsin L | -0.030814 |
| RPS23 | ribosomal protein S23 | -0.0305179 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.030486 |
| MAP7 | microtubule-associated protein 7 | -0.0300378 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0282788 |
| RPS19 | ribosomal protein S19 | -0.028108 |
| RPS29 | ribosomal protein S29 | -0.0279072 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0277916 |
| RPL34 | ribosomal protein L34 | -0.0277834 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0276416 |
| RPS13 | ribosomal protein S13 | -0.0276218 |
| IL6 | interleukin 6 | -0.0271917 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0266827 |
| STC1 | stanniocalcin 1 | -0.0266372 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0262137 |
| RAB31 | RAB31, member RAS oncogene family | -0.0258771 |
| RPS24 | ribosomal protein S24 | -0.0258436 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0258222 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0254505 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0253701 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0252933 |
| CHL1 | cell adhesion molecule L1-like | -0.0245453 |
| NCKAP5 | NCK-associated protein 5 | -0.0243926 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0237228 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0230879 |
| TENM3 | teneurin transmembrane protein 3 | -0.0229427 |
| RPL38 | ribosomal protein L38 | -0.0228683 |
| SMYD3 | SET and MYND domain containing 3 | -0.0228091 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0227838 |
| CUX1 | cut-like homeobox 1 | -0.0223197 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0221007 |
| XYLT1 | xylosyltransferase I | -0.0220684 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0217743 |
| NCOR2 | nuclear receptor corepressor 2 | -0.021691 |
| RAD51B | RAD51 paralog B | -0.0216454 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0212811 |
| LAMA5 | laminin, alpha 5 | -0.0212204 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.020924 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0207234 |
| PKM | pyruvate kinase, muscle | -0.0205656 |
| PCDH15 | protocadherin-related 15 | -0.0199531 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0198819 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0198408 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0197964 |
| EGR1 | early growth response 1 | -0.0196162 |
| RPL7A | ribosomal protein L7a | -0.0195952 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0194048 |
| RPL9 | ribosomal protein L9 | -0.0193806 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0192897 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.0192834 |
| SMAD2 | SMAD family member 2 | -0.0189513 |
| GLRX | glutaredoxin (thioltransferase) | -0.01893 |
| CADM2 | cell adhesion molecule 2 | -0.0187558 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.018666 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0186658 |
| RPS27 | ribosomal protein S27 | -0.0186198 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.018588 |
| INHBA | inhibin, beta A | -0.0185416 |
| RPL26 | ribosomal protein L26 | -0.0184333 |
| LMNA | lamin A/C | -0.0181927 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0181033 |
