| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
186 genes differentially expressed following the Plicamycin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.148983 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.113125 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.103727 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.103442 |
| GPC6 | glypican 6 | 0.102111 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0997949 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0943535 |
| EFNA5 | ephrin-A5 | 0.0941184 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0928939 |
| RLF | rearranged L-myc fusion | 0.0882084 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0858471 |
| RNF145 | ring finger protein 145 | 0.0824791 |
| MEF2A | myocyte enhancer factor 2A | 0.0769395 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.075834 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0736228 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0731572 |
| PCBP2 | poly(rC) binding protein 2 | 0.0719806 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0718369 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0708251 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0679818 |
| SBF2 | SET binding factor 2 | 0.0660664 |
| CCNY | cyclin Y | 0.0621917 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0602904 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0571031 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.056499 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0552065 |
| EGFR | epidermal growth factor receptor | 0.0551316 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.054742 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0545912 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0538108 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0535267 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0534131 |
| PDE10A | phosphodiesterase 10A | 0.0523473 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0517332 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0514671 |
| CTBP2 | C-terminal binding protein 2 | 0.0513548 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0486109 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0457545 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0454087 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0453502 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0436224 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0410679 |
| DST | dystonin | 0.0409903 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0396816 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.038554 |
| RORA | RAR-related orphan receptor A | 0.0376664 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0375949 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0374515 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0355995 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0352541 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0338153 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.031672 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0271843 |
| NDRG1 | N-myc downstream regulated 1 | 0.0253625 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0240888 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0236506 |
| GOLGA4 | golgin A4 | 0.0232933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0217491 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0200848 |
| FRMD4A | FERM domain containing 4A | 0.0194719 |
| SEPTIN7 | septin 7 | 0.0190841 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0189471 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0162901 |
| TXNRD1 | thioredoxin reductase 1 | 0.0161949 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0141381 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0140846 |
| JMJD1C | jumonji domain containing 1C | 0.013977 |
| USP34 | ubiquitin specific peptidase 34 | 0.0128627 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0124641 |
| RPL11 | ribosomal protein L11 | 0.0119135 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0113297 |
| EZR | ezrin | 0.010316 |
| TPM4 | tropomyosin 4 | 0.0103009 |
| BBX | bobby sox homolog (Drosophila) | 0.0100215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0097447 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.00921623 |
| ANKRD12 | ankyrin repeat domain 12 | 0.00861541 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00714716 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00711357 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.00677202 |
| MED13L | mediator complex subunit 13-like | 0.00554703 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00443918 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0036725 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00352493 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00231771 |
| ENO1 | enolase 1, (alpha) | 0.00147051 |
| ANXA2 | annexin A2 | 4.60398E-4 |
| PTK2 | protein tyrosine kinase 2 | 2.1019E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.227836 |
| VIM | vimentin | -0.218206 |
| FN1 | fibronectin 1 | -0.214112 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.182046 |
| TMSB10 | thymosin beta 10 | -0.117958 |
| EXT1 | exostosin glycosyltransferase 1 | -0.113082 |
| RPS6 | ribosomal protein S6 | -0.103127 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0996573 |
| RPL35A | ribosomal protein L35a | -0.0944984 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0937324 |
| PTMA | prothymosin, alpha | -0.0910473 |
| HMGA2 | high mobility group AT-hook 2 | -0.0878085 |
| RAB2A | RAB2A, member RAS oncogene family | -0.087313 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0869403 |
| RPLP1 | ribosomal protein, large, P1 | -0.0822348 |
| CALR | calreticulin | -0.0785048 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0757167 |
| SP100 | SP100 nuclear antigen | -0.0736599 |
| RTN4 | reticulon 4 | -0.0718065 |
| RPL12 | ribosomal protein L12 | -0.070294 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0695901 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0691104 |
| HDLBP | high density lipoprotein binding protein | -0.068231 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0675954 |
| RACK1 | receptor for activated C kinase 1 | -0.063246 |
| RBM25 | RNA binding motif protein 25 | -0.0630853 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0626996 |
| VCL | vinculin | -0.0570321 |
| STC1 | stanniocalcin 1 | -0.0562901 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0495807 |
| B2M | beta-2-microglobulin | -0.0485656 |
| PEG10 | paternally expressed 10 | -0.0433921 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0430978 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0420069 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0415869 |
| FTL | ferritin, light polypeptide | -0.0404236 |
| ATP11A | ATPase, class VI, type 11A | -0.0401776 |
| MORF4L2 | mortality factor 4 like 2 | -0.0400302 |
| MT2A | metallothionein 2A | -0.0388836 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0387111 |
| ATXN1 | ataxin 1 | -0.038313 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0382212 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0370197 |
| MED13 | mediator complex subunit 13 | -0.036619 |
| TXNIP | thioredoxin interacting protein | -0.0365297 |
| ZNF292 | zinc finger protein 292 | -0.0359701 |
| KIF5B | kinesin family member 5B | -0.0348484 |
| RNF213 | ring finger protein 213 | -0.0344831 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0342493 |
| PRKCA | protein kinase C, alpha | -0.0337813 |
| ASPH | aspartate beta-hydroxylase | -0.0331433 |
| RPLP0 | ribosomal protein, large, P0 | -0.0329555 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0322373 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0307524 |
| ATF6 | activating transcription factor 6 | -0.0282321 |
| RPS24 | ribosomal protein S24 | -0.0282306 |
| RPL37 | ribosomal protein L37 | -0.0275473 |
| RPS8 | ribosomal protein S8 | -0.0270465 |
| PRRC2C | proline-rich coiled-coil 2C | -0.026996 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0267128 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0257493 |
| RPL26 | ribosomal protein L26 | -0.0257437 |
| MYO1E | myosin IE | -0.023878 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0234445 |
| CADM2 | cell adhesion molecule 2 | -0.0231688 |
| RPS27A | ribosomal protein S27a | -0.0227953 |
| PHF3 | PHD finger protein 3 | -0.0215249 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0203191 |
| PGK1 | phosphoglycerate kinase 1 | -0.0202384 |
| CCNI | cyclin I | -0.0201046 |
| DSCAM | Down syndrome cell adhesion molecule | -0.020039 |
| SPAG9 | sperm associated antigen 9 | -0.0178443 |
| SETD5 | SET domain containing 5 | -0.016973 |
| LMNA | lamin A/C | -0.0160858 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0160815 |
| ARRDC3 | arrestin domain containing 3 | -0.0160659 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0157493 |
| RBM39 | RNA binding motif protein 39 | -0.0146751 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0142654 |
| CANX | calnexin | -0.0130114 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.01249 |
| TAOK1 | TAO kinase 1 | -0.0116249 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0109958 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00981998 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00900312 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00863549 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.00860473 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.00714387 |
| GOLGB1 | golgin B1 | -0.00658514 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00600946 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.00581866 |
| RPLP2 | ribosomal protein, large, P2 | -0.00406861 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0038943 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.00361571 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00311067 |
| PARD3 | par-3 family cell polarity regulator | -0.002802 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00244633 |
| MACF1 | microtubule-actin crosslinking factor 1 | -1.18945E-4 |
