| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Plicamycin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.141008 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.115395 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0895475 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0569064 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0537678 |
| PTMA | prothymosin, alpha | 0.0508781 |
| SET | SET nuclear proto-oncogene | 0.0453265 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0410647 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0392553 |
| WDR43 | WD repeat domain 43 | 0.0384934 |
| MATR3 | matrin 3 | 0.0380556 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0375911 |
| TMSB4X | thymosin beta 4, X-linked | 0.0366188 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0358653 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0338002 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0336432 |
| HMGA2 | high mobility group AT-hook 2 | 0.0320254 |
| TPM3 | tropomyosin 3 | 0.0311299 |
| MSN | moesin | 0.0305822 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0299905 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0294046 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0288297 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0286286 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0270972 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0266886 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0261027 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0259127 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0250965 |
| RBM25 | RNA binding motif protein 25 | 0.0250164 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0249543 |
| ZNF292 | zinc finger protein 292 | 0.0248123 |
| ANLN | anillin, actin binding protein | 0.0247345 |
| STRN | striatin, calmodulin binding protein | 0.0246913 |
| FERMT2 | fermitin family member 2 | 0.0245211 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0241296 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0240836 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0239544 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.023939 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0235949 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0232253 |
| GOLGA4 | golgin A4 | 0.0231909 |
| USP3 | ubiquitin specific peptidase 3 | 0.022834 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0227944 |
| NFIB | nuclear factor I/B | 0.0227503 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.0227289 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0224107 |
| PAPOLA | poly(A) polymerase alpha | 0.0222743 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0221653 |
| SIK3 | SIK family kinase 3 | 0.0221135 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0220889 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0220451 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0219857 |
| DSTN | destrin (actin depolymerizing factor) | 0.021792 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0216877 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0215224 |
| H1-4 | H1.4 linker histone, cluster member | 0.0214699 |
| POTEF | POTE ankyrin domain family, member F | 0.0214489 |
| CFL2 | cofilin 2 (muscle) | 0.0214063 |
| NCKAP1 | NCK-associated protein 1 | 0.021309 |
| CDC73 | cell division cycle 73 | 0.0212991 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0211188 |
| CCNL1 | cyclin L1 | 0.0211169 |
| IPO7 | importin 7 | 0.0209823 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.020797 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0207596 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0206087 |
| OLA1 | Obg-like ATPase 1 | 0.0204157 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0203229 |
| MEMO1 | mediator of cell motility 1 | 0.0202655 |
| YBX3 | Y box binding protein 3 | 0.0201919 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0201913 |
| RPL7 | ribosomal protein L7 | 0.0201721 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0200376 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0197534 |
| MKI67 | marker of proliferation Ki-67 | 0.0191032 |
| TFG | TRK-fused gene | 0.0190657 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0189338 |
| PDE10A | phosphodiesterase 10A | 0.0188826 |
| RPL3 | ribosomal protein L3 | 0.0188139 |
| RPL19 | ribosomal protein L19 | 0.0187822 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0187229 |
| GLO1 | glyoxalase I | 0.0187006 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0186758 |
| ANXA1 | annexin A1 | 0.0186577 |
| PFN1 | profilin 1 | 0.0185134 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0184939 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0184744 |
| USP6NL | USP6 N-terminal like | 0.0183331 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0181272 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0181091 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0180848 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0179541 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0178698 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0176732 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0176003 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0175502 |
| XPO1 | exportin 1 | 0.0175296 |
| RTN4 | reticulon 4 | 0.0175189 |
| SMAD4 | SMAD family member 4 | 0.0173549 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.017321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.16268 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.150737 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.140197 |
| GPC3 | glypican 3 | -0.130799 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.128137 |
| COL11A1 | collagen, type XI, alpha 1 | -0.121314 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.117413 |
| CADM2 | cell adhesion molecule 2 | -0.116303 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.11205 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.111889 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.10425 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0951146 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0909231 |
| NTM | neurotrimin | -0.0904653 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0849515 |
| PHIP | pleckstrin homology domain interacting protein | -0.0827938 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0723042 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.071565 |
| COL1A2 | collagen, type I, alpha 2 | -0.0707385 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0692188 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.067271 |
| PCDH9 | protocadherin 9 | -0.066219 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.066133 |
| PEG10 | paternally expressed 10 | -0.0648198 |
| COL3A1 | collagen, type III, alpha 1 | -0.0639363 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0604955 |
| RPS16 | ribosomal protein S16 | -0.0586826 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0571044 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0558935 |
| MAP4 | microtubule-associated protein 4 | -0.0557412 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0545917 |
| LRRC4C | leucine rich repeat containing 4C | -0.0543734 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0515465 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0506743 |
| RAD51B | RAD51 paralog B | -0.0488407 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0480872 |
| LPIN2 | lipin 2 | -0.0470084 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0468144 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0466329 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0465879 |
| RPS8 | ribosomal protein S8 | -0.0457726 |
| PLPP1 | phospholipid phosphatase 1 | -0.045569 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0451347 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0446781 |
| THOC2 | THO complex 2 | -0.0414028 |
| MYO10 | myosin X | -0.0413795 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0406379 |
| SNX6 | sorting nexin 6 | -0.0403143 |
| PRTG | protogenin | -0.0401853 |
| CDH19 | cadherin 19, type 2 | -0.0394208 |
| VIM | vimentin | -0.0393824 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0393567 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0391653 |
| TMSB10 | thymosin beta 10 | -0.0389404 |
| GSE1 | Gse1 coiled-coil protein | -0.0387118 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0386553 |
| RFPL4B | ret finger protein-like 4B | -0.0385989 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0385069 |
| PRKD1 | protein kinase D1 | -0.0383716 |
| GNAS | GNAS complex locus | -0.0383395 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0378558 |
| AHNAK | AHNAK nucleoprotein | -0.0378482 |
| ZNF385D | zinc finger protein 385D | -0.0363154 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0362469 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0357599 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0354581 |
| TOX | thymocyte selection-associated high mobility group box | -0.0347275 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0342717 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0340178 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0337872 |
| NEBL | nebulette | -0.0337452 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0337405 |
| TENM3 | teneurin transmembrane protein 3 | -0.0335966 |
| MEIS2 | Meis homeobox 2 | -0.0335535 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0333483 |
| PHF21A | PHD finger protein 21A | -0.0331291 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0330098 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.032671 |
| SMYD3 | SET and MYND domain containing 3 | -0.0325823 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0320313 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0316401 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0315552 |
| HMCN1 | hemicentin 1 | -0.0313989 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.031187 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0311681 |
| EMP1 | epithelial membrane protein 1 | -0.0310332 |
| HDAC9 | histone deacetylase 9 | -0.0309901 |
| RPL35A | ribosomal protein L35a | -0.030717 |
| NXN | nucleoredoxin | -0.0305405 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.030225 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0301487 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0298654 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0295643 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0295624 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0291068 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0288888 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0287762 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0287269 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0286973 |
| NPAS3 | neuronal PAS domain protein 3 | -0.028262 |
