| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.120621 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0830055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0716558 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0704814 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.069227 |
| PTMA | prothymosin, alpha | 0.0677668 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0648592 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0636624 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0610298 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0534722 |
| PGK1 | phosphoglycerate kinase 1 | 0.0533524 |
| ZNF292 | zinc finger protein 292 | 0.051303 |
| ECT2 | epithelial cell transforming 2 | 0.0495547 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0480743 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0463046 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0446117 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0425093 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0394493 |
| MATR3 | matrin 3 | 0.0390768 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0382269 |
| GOLGA4 | golgin A4 | 0.0370301 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.03499 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0347396 |
| OGA | O-GlcNAcase | 0.0346678 |
| ENO1 | enolase 1, (alpha) | 0.0346674 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0334852 |
| SQSTM1 | sequestosome 1 | 0.0324644 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0318802 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.031573 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0304068 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0296568 |
| HELZ | helicase with zinc finger | 0.0294677 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0293667 |
| APP | amyloid beta (A4) precursor protein | 0.0283911 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0283745 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0283356 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0282474 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0278237 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.027654 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0271464 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0266086 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0265878 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0260963 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0256811 |
| INSIG2 | insulin induced gene 2 | 0.0252169 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0248119 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0247829 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0246461 |
| CANX | calnexin | 0.024093 |
| USP3 | ubiquitin specific peptidase 3 | 0.0238523 |
| RNF145 | ring finger protein 145 | 0.0237338 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0235061 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0234262 |
| CDC73 | cell division cycle 73 | 0.0233302 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0228284 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.022814 |
| TFG | TRK-fused gene | 0.022792 |
| SLMAP | sarcolemma associated protein | 0.0224537 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0222598 |
| PRELID2 | PRELI domain containing 2 | 0.0222352 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0222037 |
| FAT1 | FAT atypical cadherin 1 | 0.0218955 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.02174 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0215844 |
| CASC3 | cancer susceptibility candidate 3 | 0.0215464 |
| ASPH | aspartate beta-hydroxylase | 0.0213349 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.021298 |
| QKI | QKI, KH domain containing, RNA binding | 0.0212691 |
| NDRG1 | N-myc downstream regulated 1 | 0.0211086 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0208946 |
| SRP54 | signal recognition particle 54kDa | 0.0208377 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0206438 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0206213 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0205631 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0204781 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0204306 |
| MYOF | myoferlin | 0.0203025 |
| RBM39 | RNA binding motif protein 39 | 0.0201892 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0201347 |
| NCKAP1 | NCK-associated protein 1 | 0.0200992 |
| SNX14 | sorting nexin 14 | 0.0199794 |
| TXNIP | thioredoxin interacting protein | 0.0199734 |
| TOP1 | topoisomerase (DNA) I | 0.0199545 |
| INTS6 | integrator complex subunit 6 | 0.0198586 |
| EZR | ezrin | 0.0198094 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0193564 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0193407 |
| PCBP2 | poly(rC) binding protein 2 | 0.0192443 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0192132 |
| RPL4 | ribosomal protein L4 | 0.0190905 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0189463 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0189355 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0189165 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0188969 |
| WDR45B | WD repeat domain 45B | 0.0188897 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0187993 |
| XPO1 | exportin 1 | 0.0187272 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0184513 |
| RAB14 | RAB14, member RAS oncogene family | 0.0183496 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0183443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.276771 |
| PKM | pyruvate kinase, muscle | -0.157205 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.136936 |
| FOXP1 | forkhead box P1 | -0.130326 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0987724 |
| RPS6 | ribosomal protein S6 | -0.0974928 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0907783 |
| EGFR | epidermal growth factor receptor | -0.0904119 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0849885 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0768352 |
| NBEA | neurobeachin | -0.0720533 |
| TJP1 | tight junction protein 1 | -0.0699471 |
| AHNAK | AHNAK nucleoprotein | -0.0667478 |
| VCL | vinculin | -0.0664131 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0608111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0596741 |
| BMP10 | bone morphogenetic protein 10 | -0.0590328 |
| CCND1 | cyclin D1 | -0.0579565 |
| TXNRD1 | thioredoxin reductase 1 | -0.0567001 |
| RPL35A | ribosomal protein L35a | -0.0566087 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0540587 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0535173 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0534274 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.052174 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.049466 |
| FLNB | filamin B, beta | -0.0494385 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0489946 |
| POTEF | POTE ankyrin domain family, member F | -0.0486886 |
| PFN1 | profilin 1 | -0.0482837 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0455453 |
| RPL34 | ribosomal protein L34 | -0.0439066 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0438499 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0434302 |
| ACTG1 | actin gamma 1 | -0.0431579 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0419996 |
| RPS8 | ribosomal protein S8 | -0.0417419 |
| GSE1 | Gse1 coiled-coil protein | -0.0406728 |
| S100A4 | S100 calcium binding protein A4 | -0.0404257 |
| GLI3 | GLI family zinc finger 3 | -0.0394266 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0393579 |
| RIGI | RNA sensor RIG-I | -0.0393371 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0391745 |
| ZNF438 | zinc finger protein 438 | -0.038776 |
| EXOC6B | exocyst complex component 6B | -0.0384009 |
| GLI2 | GLI family zinc finger 2 | -0.0382895 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0382298 |
| RPS23 | ribosomal protein S23 | -0.0370881 |
| RPS19 | ribosomal protein S19 | -0.0368246 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.036246 |
| OSMR | oncostatin M receptor | -0.0357758 |
| RPL19 | ribosomal protein L19 | -0.0348462 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0348439 |
| HDAC9 | histone deacetylase 9 | -0.0345397 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0345293 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.034464 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0339622 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0336685 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.033551 |
| BPTF | bromodomain PHD finger transcription factor | -0.0331682 |
| MLIP | muscular LMNA-interacting protein | -0.0328345 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0323556 |
| RPLP2 | ribosomal protein, large, P2 | -0.0322813 |
| CUX1 | cut-like homeobox 1 | -0.0322665 |
| PHF14 | PHD finger protein 14 | -0.0321162 |
| SP100 | SP100 nuclear antigen | -0.0320735 |
| SMIM44 | small integral membrane protein 44 | -0.0316649 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.0316524 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0312845 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.031257 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0312409 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0309921 |
| RPL31 | ribosomal protein L31 | -0.0303065 |
| RPL32 | ribosomal protein L32 | -0.0301782 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0298882 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0297461 |
| PRDX2 | peroxiredoxin 2 | -0.0297003 |
| ASTN2 | astrotactin 2 | -0.0292781 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0289838 |
| S100A9 | S100 calcium binding protein A9 | -0.028981 |
| RPS14 | ribosomal protein S14 | -0.0288943 |
| RPLP1 | ribosomal protein, large, P1 | -0.0285914 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0283835 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0283447 |
| RPL12 | ribosomal protein L12 | -0.0279686 |
| ARHGAP25 | Rho GTPase activating protein 25 | -0.0276595 |
| RPL8 | ribosomal protein L8 | -0.0273461 |
| LATS2 | large tumor suppressor kinase 2 | -0.0273155 |
| SEPTIN9 | septin 9 | -0.0271475 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0271462 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0271076 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0268628 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0268373 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0268193 |
| TOB1 | transducer of ERBB2, 1 | -0.0264662 |
| TRERF1 | transcriptional regulating factor 1 | -0.0260984 |
| TMEM65 | transmembrane protein 65 | -0.0256946 |
| RPL23 | ribosomal protein L23 | -0.0255998 |
| RPS15 | ribosomal protein S15 | -0.0255131 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0252708 |
| MTAP | methylthioadenosine phosphorylase | -0.0252536 |
