| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.122191 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.11835 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.114152 |
| PTMA | prothymosin, alpha | 0.0640059 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0579835 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0557261 |
| OGA | O-GlcNAcase | 0.0483747 |
| NAV2 | neuron navigator 2 | 0.0476461 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.046972 |
| RPS12 | ribosomal protein S12 | 0.0469116 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0459253 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0429715 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0424733 |
| ZNF292 | zinc finger protein 292 | 0.0421683 |
| MSN | moesin | 0.0420555 |
| SPAG9 | sperm associated antigen 9 | 0.04178 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0402809 |
| MATR3 | matrin 3 | 0.0398743 |
| ARRDC3 | arrestin domain containing 3 | 0.0370023 |
| TSC22D2 | TSC22 domain family, member 2 | 0.035186 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0345305 |
| TMSB4X | thymosin beta 4, X-linked | 0.0344371 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0326848 |
| RPLP0 | ribosomal protein, large, P0 | 0.0325272 |
| GOLGA4 | golgin A4 | 0.032171 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0318674 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0315682 |
| RPL7 | ribosomal protein L7 | 0.0313067 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0309185 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0308567 |
| ANLN | anillin, actin binding protein | 0.0307126 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0304858 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0299346 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.029483 |
| CADM1 | cell adhesion molecule 1 | 0.0293402 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0290668 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0284751 |
| HMGB2 | high mobility group box 2 | 0.0279605 |
| CENPF | centromere protein F, 350/400kDa | 0.0278253 |
| RNF145 | ring finger protein 145 | 0.0277708 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0275155 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0269593 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0266533 |
| USP37 | ubiquitin specific peptidase 37 | 0.0265365 |
| ATP13A3 | ATPase type 13A3 | 0.0265077 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0260704 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.025471 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0253694 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0245942 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0245918 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0244924 |
| NGLY1 | N-glycanase 1 | 0.0243335 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0229936 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0225065 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0222306 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0221868 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0217359 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0215061 |
| SERINC1 | serine incorporator 1 | 0.0214856 |
| AFDN | afadin, adherens junction formation factor | 0.0214688 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0214118 |
| PTK2 | protein tyrosine kinase 2 | 0.021067 |
| MKI67 | marker of proliferation Ki-67 | 0.0208636 |
| DIAPH3 | diaphanous-related formin 3 | 0.0207812 |
| APP | amyloid beta (A4) precursor protein | 0.0204462 |
| MYOF | myoferlin | 0.0204092 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0204058 |
| TMF1 | TATA element modulatory factor 1 | 0.0203711 |
| ZNF451 | zinc finger protein 451 | 0.0200631 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0200543 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0199974 |
| RPS6 | ribosomal protein S6 | 0.0199518 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0199247 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0196803 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0195627 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0194855 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0194571 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0193646 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0193469 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0189904 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0187276 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0187021 |
| FLOT1 | flotillin 1 | 0.0184199 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0184108 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0181762 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0180257 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0179764 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0178513 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0177478 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0177349 |
| SUCO | SUN domain containing ossification factor | 0.0175976 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0173327 |
| XPO1 | exportin 1 | 0.0173231 |
| FMNL2 | formin-like 2 | 0.0173048 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.017236 |
| RLF | rearranged L-myc fusion | 0.0172176 |
| ZNF148 | zinc finger protein 148 | 0.0171991 |
| SET | SET nuclear proto-oncogene | 0.0171822 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0171625 |
| RAI1 | retinoic acid induced 1 | 0.0170795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157435 |
| VIM | vimentin | -0.154391 |
| GLIS3 | GLIS family zinc finger 3 | -0.139868 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.138778 |
| HLA-B | major histocompatibility complex, class I, B | -0.135224 |
| FN1 | fibronectin 1 | -0.135223 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.118245 |
| FRMD4A | FERM domain containing 4A | -0.109199 |
| FTL | ferritin, light polypeptide | -0.108776 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.103354 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0870403 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0800645 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0769977 |
| IER3 | immediate early response 3 | -0.0761865 |
| BICC1 | BicC family RNA binding protein 1 | -0.0745545 |
| VCAN | versican | -0.0694554 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0675636 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0674361 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0672308 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0671649 |
| HLA-A | major histocompatibility complex, class I, A | -0.066311 |
| CDH13 | cadherin 13 | -0.0654186 |
| DST | dystonin | -0.0638144 |
| HMGA2 | high mobility group AT-hook 2 | -0.0625637 |
| LDHA | lactate dehydrogenase A | -0.0597871 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0547717 |
| EGR1 | early growth response 1 | -0.0542073 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0538654 |
| DIAPH2 | diaphanous-related formin 2 | -0.0528938 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0511131 |
| CD44 | CD44 molecule (Indian blood group) | -0.050076 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0500617 |
| VCL | vinculin | -0.0499168 |
| RAI14 | retinoic acid induced 14 | -0.0498477 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0467631 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0465029 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0455547 |
| PDE10A | phosphodiesterase 10A | -0.0451663 |
| ADM | adrenomedullin | -0.0447678 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0443582 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0437284 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0436665 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.043518 |
| COL1A1 | collagen, type I, alpha 1 | -0.0428573 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0422792 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0420172 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.041295 |
| NDRG1 | N-myc downstream regulated 1 | -0.0408029 |
| RND3 | Rho family GTPase 3 | -0.0401721 |
| TMEM132D | transmembrane protein 132D | -0.0393575 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0392043 |
| TMSB10 | thymosin beta 10 | -0.0390747 |
| C3 | complement component 3 | -0.038975 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0389672 |
| LOX | lysyl oxidase | -0.0388578 |
| HDAC9 | histone deacetylase 9 | -0.0388532 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0384549 |
| CTSD | cathepsin D | -0.0374003 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0372309 |
| TNS3 | tensin 3 | -0.0371834 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0361696 |
| CTSB | cathepsin B | -0.0361577 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0356798 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0356398 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0355518 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0351488 |
| NAV1 | neuron navigator 1 | -0.0343771 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0335885 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0332491 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0331669 |
| COL5A1 | collagen, type V, alpha 1 | -0.033142 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0329451 |
| COL1A2 | collagen, type I, alpha 2 | -0.0325958 |
| STC2 | stanniocalcin 2 | -0.0325866 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0313847 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0311465 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0308168 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0308077 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0305401 |
| NABP1 | nucleic acid binding protein 1 | -0.0298749 |
| RRBP1 | ribosome binding protein 1 | -0.0298584 |
| MLPH | melanophilin | -0.029782 |
| PLIN2 | perilipin 2 | -0.029773 |
| CLMP | CXADR-like membrane protein | -0.0293415 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0293046 |
| AHNAK | AHNAK nucleoprotein | -0.0291734 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0288911 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0285324 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0285236 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.028142 |
| HMGA1 | high mobility group AT-hook 1 | -0.0280607 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0280104 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0278846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0276659 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0275165 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0272582 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0268548 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0267084 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0266811 |
| KYNU | kynureninase | -0.0264975 |
