| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Plicamycin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF395 | zinc finger protein 395 | 0.0615139 |
| PRELID2 | PRELI domain containing 2 | 0.0580335 |
| NAV2 | neuron navigator 2 | 0.0554421 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0528217 |
| PTK2 | protein tyrosine kinase 2 | 0.0477271 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0461683 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.044753 |
| EGFR | epidermal growth factor receptor | 0.0427278 |
| METTL15 | methyltransferase like 15 | 0.0424971 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0404989 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0397342 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0395492 |
| RNF145 | ring finger protein 145 | 0.0371605 |
| TPM3 | tropomyosin 3 | 0.0366468 |
| FAM13A | family with sequence similarity 13, member A | 0.0365739 |
| CALR | calreticulin | 0.0364206 |
| DENND4C | DENN/MADD domain containing 4C | 0.0363911 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0354773 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0353319 |
| PGK1 | phosphoglycerate kinase 1 | 0.0348303 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0343692 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0323421 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0319968 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0314816 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0310277 |
| EXOC4 | exocyst complex component 4 | 0.0307009 |
| CUL3 | cullin 3 | 0.0296883 |
| MSN | moesin | 0.0293954 |
| COL11A1 | collagen, type XI, alpha 1 | 0.029241 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0287697 |
| RPS18 | ribosomal protein S18 | 0.0287613 |
| HMGA1 | high mobility group AT-hook 1 | 0.0287211 |
| RPL3 | ribosomal protein L3 | 0.0286667 |
| BBX | bobby sox homolog (Drosophila) | 0.0282105 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0281261 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.028045 |
| MCL1 | myeloid cell leukemia 1 | 0.0279741 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0273267 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0267567 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0267435 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0263946 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0259986 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256893 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0252666 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.025092 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0249858 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0248095 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0247302 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0247221 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0244356 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0244154 |
| MYO10 | myosin X | 0.0241961 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0241635 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0241173 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0239179 |
| RBM27 | RNA binding motif protein 27 | 0.0237836 |
| RSF1 | remodeling and spacing factor 1 | 0.0233246 |
| HYOU1 | hypoxia up-regulated 1 | 0.023288 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0231944 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0231337 |
| VEGFA | vascular endothelial growth factor A | 0.0221526 |
| GOLGA2 | golgin A2 | 0.0219741 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0217901 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0217424 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0214365 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0212908 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0212679 |
| RBM25 | RNA binding motif protein 25 | 0.0211468 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210012 |
| SRPK2 | SRSF protein kinase 2 | 0.0209874 |
| NRXN3 | neurexin 3 | 0.0208716 |
| FRMD5 | FERM domain containing 5 | 0.0208228 |
| THOC2 | THO complex 2 | 0.0208207 |
| RPL21 | ribosomal protein L21 | 0.0207608 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0206541 |
| ICE2 | interactor of little elongation complex ELL subunit 2 | 0.0206535 |
| RASA3 | RAS p21 protein activator 3 | 0.0205942 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.02056 |
| EFNA5 | ephrin-A5 | 0.020484 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0203965 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0202082 |
| FAM219A | family with sequence similarity 219, member A | 0.0200781 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0200576 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0200424 |
| SMYD3 | SET and MYND domain containing 3 | 0.0200101 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0198808 |
| WDR41 | WD repeat domain 41 | 0.019835 |
| MYLK | myosin light chain kinase | 0.0197742 |
| GPR107 | G protein-coupled receptor 107 | 0.0196714 |
| STC2 | stanniocalcin 2 | 0.0196409 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0195394 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0195112 |
| SEPTIN9 | septin 9 | 0.019388 |
| JMJD1C | jumonji domain containing 1C | 0.0193185 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0192136 |
| ATXN1 | ataxin 1 | 0.0190637 |
| FRMD6 | FERM domain containing 6 | 0.0190125 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0189329 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0189317 |
| BPTF | bromodomain PHD finger transcription factor | 0.0188421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.379403 |
| HLA-B | major histocompatibility complex, class I, B | -0.139478 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133022 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.119073 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.100705 |
| TMSB10 | thymosin beta 10 | -0.0820424 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0792138 |
| B2M | beta-2-microglobulin | -0.0790669 |
| COL1A1 | collagen, type I, alpha 1 | -0.0781772 |
| FTL | ferritin, light polypeptide | -0.0760985 |
| STC1 | stanniocalcin 1 | -0.075827 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0705346 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0702038 |
| VIM | vimentin | -0.0658726 |
| CAVIN1 | caveolae associated protein 1 | -0.0645088 |
| COL1A2 | collagen, type I, alpha 2 | -0.0640422 |
| LOX | lysyl oxidase | -0.0636858 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0633772 |
| CCNI | cyclin I | -0.0617804 |
| MT2A | metallothionein 2A | -0.0580141 |
| HDLBP | high density lipoprotein binding protein | -0.0578226 |
| ANXA2 | annexin A2 | -0.0550124 |
| MAP1B | microtubule-associated protein 1B | -0.0533959 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0532666 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0530447 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0523322 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0519055 |
| SDC4 | syndecan 4 | -0.0503784 |
| CALU | calumenin | -0.0502848 |
| FUS | FUS RNA binding protein | -0.0502395 |
| S100A10 | S100 calcium binding protein A10 | -0.0490719 |
| PRSS23 | protease, serine, 23 | -0.0486765 |
| UBC | ubiquitin C | -0.0456645 |
| LOXL2 | lysyl oxidase-like 2 | -0.0453147 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0452658 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0448367 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0441967 |
| HLA-A | major histocompatibility complex, class I, A | -0.0440694 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0439608 |
| HLA-C | major histocompatibility complex, class I, C | -0.0438461 |
| MT1X | metallothionein 1X | -0.043073 |
| MYOF | myoferlin | -0.0430618 |
| OGA | O-GlcNAcase | -0.0428835 |
| PRRC1 | proline-rich coiled-coil 1 | -0.041955 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0417279 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0416895 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.041674 |
| RTN4 | reticulon 4 | -0.0414291 |
| CD44 | CD44 molecule (Indian blood group) | -0.041171 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0400661 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0396131 |
| HM13 | histocompatibility (minor) 13 | -0.0394185 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.039082 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0386614 |
| COG5 | component of oligomeric golgi complex 5 | -0.0384958 |
| AHNAK | AHNAK nucleoprotein | -0.0383207 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.037774 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0377357 |
| PTMA | prothymosin, alpha | -0.0368771 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0368752 |
| RLF | rearranged L-myc fusion | -0.0366001 |
| RPL28 | ribosomal protein L28 | -0.0365164 |
| MTPN | myotrophin | -0.0359981 |
| RPLP1 | ribosomal protein, large, P1 | -0.0358221 |
| MORF4L2 | mortality factor 4 like 2 | -0.035472 |
| ARF1 | ADP-ribosylation factor 1 | -0.0352834 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0346008 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0344616 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0343427 |
| KLHDC10 | kelch domain containing 10 | -0.0340239 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0338248 |
| GLIS3 | GLIS family zinc finger 3 | -0.0337069 |
| ZNF207 | zinc finger protein 207 | -0.03366 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0335349 |
| TXNIP | thioredoxin interacting protein | -0.0335149 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0330765 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0328667 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0324973 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0324858 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0324797 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0321738 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0321368 |
| RHEB | Ras homolog enriched in brain | -0.0318928 |
| CD99 | CD99 molecule | -0.0314097 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0307695 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0304773 |
| THY1 | Thy-1 cell surface antigen | -0.0304602 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0299882 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0299414 |
| ITM2B | integral membrane protein 2B | -0.0298822 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.029759 |
| RND3 | Rho family GTPase 3 | -0.0295037 |
| RAB10 | RAB10, member RAS oncogene family | -0.0293516 |
| AHR | aryl hydrocarbon receptor | -0.0289507 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0289329 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0289292 |
| NABP1 | nucleic acid binding protein 1 | -0.0286734 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0285845 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0284648 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0278529 |