| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Plicamycin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0637375 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0579826 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0512165 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0487615 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0444503 |
| GOLGA4 | golgin A4 | 0.0421472 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0396188 |
| CANX | calnexin | 0.0362764 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0326737 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0322962 |
| SETD5 | SET domain containing 5 | 0.0318682 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0316034 |
| NUP58 | nucleoporin 58 | 0.0315217 |
| PCBP2 | poly(rC) binding protein 2 | 0.0313062 |
| SET | SET nuclear proto-oncogene | 0.0291836 |
| ECT2 | epithelial cell transforming 2 | 0.0291403 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0287708 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0287518 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0285179 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0280588 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0272044 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0271575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0270977 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0268111 |
| HELZ | helicase with zinc finger | 0.0265665 |
| CLTC | clathrin, heavy chain (Hc) | 0.0261452 |
| ETNK1 | ethanolamine kinase 1 | 0.0260651 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.025525 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0249844 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.024945 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0241297 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0236016 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0233072 |
| KIAA1958 | KIAA1958 | 0.0230781 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0229935 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.022897 |
| SNX13 | sorting nexin 13 | 0.0227572 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0221716 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0220893 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0218156 |
| TPR | translocated promoter region, nuclear basket protein | 0.0216918 |
| TXNRD1 | thioredoxin reductase 1 | 0.021611 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0215879 |
| TMF1 | TATA element modulatory factor 1 | 0.0215737 |
| YBX1 | Y box binding protein 1 | 0.0215311 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0212592 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0209159 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0207068 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0202747 |
| FANCI | Fanconi anemia, complementation group I | 0.0201327 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0199342 |
| CASC3 | cancer susceptibility candidate 3 | 0.0198562 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0198165 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0198101 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0197208 |
| MED17 | mediator complex subunit 17 | 0.0195542 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0194698 |
| XPO1 | exportin 1 | 0.0194652 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.019432 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.019428 |
| COPA | coatomer protein complex, subunit alpha | 0.019427 |
| WDR43 | WD repeat domain 43 | 0.0193966 |
| MATR3 | matrin 3 | 0.0192183 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0190209 |
| GOLT1B | golgi transport 1B | 0.0188201 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0187184 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0182128 |
| CAPRIN1 | cell cycle associated protein 1 | 0.018157 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0181532 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0180667 |
| ATP13A3 | ATPase type 13A3 | 0.0178377 |
| TPM3 | tropomyosin 3 | 0.0178372 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0178059 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0177836 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0177804 |
| CEP95 | centrosomal protein 95kDa | 0.0177123 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0177035 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0176949 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0175519 |
| TBC1D15 | TBC1 domain family, member 15 | 0.017533 |
| TTK | TTK protein kinase | 0.0174359 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0173486 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0173141 |
| CENPF | centromere protein F, 350/400kDa | 0.0173083 |
| SUCO | SUN domain containing ossification factor | 0.0172487 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0171379 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0171193 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0170555 |
| NCKAP1 | NCK-associated protein 1 | 0.0170067 |
| SAFB | scaffold attachment factor B | 0.0170052 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.016999 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0169364 |
| RPS12 | ribosomal protein S12 | 0.0168679 |
| SPAG9 | sperm associated antigen 9 | 0.0168258 |
| SRP54 | signal recognition particle 54kDa | 0.016817 |
| ORC4 | origin recognition complex, subunit 4 | 0.016657 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0166004 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0165797 |
| ATXN2 | ataxin 2 | 0.0164876 |
| CALR | calreticulin | 0.0164344 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.411397 |
| FNDC3B | fibronectin type III domain containing 3B | -0.133955 |
| TMSB10 | thymosin beta 10 | -0.110522 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.10103 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0773955 |
| VIM | vimentin | -0.0752068 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0696286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0693483 |
| DST | dystonin | -0.0680867 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0680738 |
| PKM | pyruvate kinase, muscle | -0.0646759 |
| CD44 | CD44 molecule (Indian blood group) | -0.0605916 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0594652 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0593654 |
| PRKCA | protein kinase C, alpha | -0.0573042 |
| EGR1 | early growth response 1 | -0.0565476 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.054132 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0525459 |
| FMNL2 | formin-like 2 | -0.0522944 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0517941 |
| ANGPTL4 | angiopoietin-like 4 | -0.051382 |
| HMGA2 | high mobility group AT-hook 2 | -0.0512633 |
| LDHA | lactate dehydrogenase A | -0.0497606 |
| IGF2 | insulin-like growth factor 2 | -0.0485082 |
| RPLP1 | ribosomal protein, large, P1 | -0.0478446 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0475655 |
| ATXN1 | ataxin 1 | -0.0463637 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0461836 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0452314 |
| RIGI | RNA sensor RIG-I | -0.0450867 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0448768 |
| RPL35A | ribosomal protein L35a | -0.0429796 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0428665 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0408789 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0401172 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0391843 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0389585 |
| RORA | RAR-related orphan receptor A | -0.0372881 |
| SVIL | supervillin | -0.0370509 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.036873 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0362575 |
| VMP1 | vacuole membrane protein 1 | -0.0355009 |
| PRSS23 | protease, serine, 23 | -0.0352068 |
| ANXA2 | annexin A2 | -0.0351367 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0350319 |
| RAI14 | retinoic acid induced 14 | -0.034528 |
| OSMR | oncostatin M receptor | -0.0344925 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0343569 |
| ATG7 | autophagy related 7 | -0.0341851 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.033602 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0335426 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0333363 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0332645 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0331127 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0329397 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0327414 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0326518 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0325721 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.032429 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0323543 |
| FMN1 | formin 1 | -0.0323028 |
| FLNB | filamin B, beta | -0.0320341 |
| PRR16 | proline rich 16 | -0.0316198 |
| ERBIN | erbb2 interacting protein | -0.0313269 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0311164 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310535 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0310419 |
| NALCN | sodium leak channel, non selective | -0.0310158 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0309244 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0307841 |
| BPTF | bromodomain PHD finger transcription factor | -0.030575 |
| DNER | delta/notch-like EGF repeat containing | -0.0301597 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0301348 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0300698 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0299743 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0295251 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0294211 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0292943 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0292399 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0288082 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0286863 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0286687 |
| PCED1B | PC-esterase domain containing 1B | -0.028328 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282616 |
| MT2A | metallothionein 2A | -0.0280844 |
| RAD51B | RAD51 paralog B | -0.0280076 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0279954 |
| INTS6 | integrator complex subunit 6 | -0.0278438 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0276551 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0265655 |
| ZNF609 | zinc finger protein 609 | -0.0263383 |
| AHNAK | AHNAK nucleoprotein | -0.0262692 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0262291 |
| NBEA | neurobeachin | -0.0261288 |
| IL6ST | interleukin 6 signal transducer | -0.0259653 |
| FAM3C | family with sequence similarity 3, member C | -0.0259597 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0256846 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0251592 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0249814 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0249613 |
