| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Plicamycin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Plicamycin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.124744 |
| PTMA | prothymosin, alpha | 0.102516 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0994483 |
| CANX | calnexin | 0.0940538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0864219 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0860999 |
| FAM13A | family with sequence similarity 13, member A | 0.0712874 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0686907 |
| RNF145 | ring finger protein 145 | 0.0615458 |
| GOLGA4 | golgin A4 | 0.058746 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0575044 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0546113 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0524382 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0494221 |
| HELZ | helicase with zinc finger | 0.0490755 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0490678 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0462551 |
| ZNF292 | zinc finger protein 292 | 0.045538 |
| PGK1 | phosphoglycerate kinase 1 | 0.0438203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0436308 |
| NDRG1 | N-myc downstream regulated 1 | 0.0416876 |
| OGA | O-GlcNAcase | 0.0405295 |
| RPS12 | ribosomal protein S12 | 0.040364 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0398881 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0392277 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0391102 |
| MT2A | metallothionein 2A | 0.0385406 |
| CD109 | CD109 molecule | 0.038209 |
| RAB18 | RAB18, member RAS oncogene family | 0.0380787 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0377629 |
| MATR3 | matrin 3 | 0.037455 |
| SUCO | SUN domain containing ossification factor | 0.036574 |
| PCBP2 | poly(rC) binding protein 2 | 0.0363225 |
| APP | amyloid beta (A4) precursor protein | 0.0355799 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.034367 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0342199 |
| TFG | TRK-fused gene | 0.0331162 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.032987 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0326722 |
| CALR | calreticulin | 0.032563 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0323655 |
| XPO1 | exportin 1 | 0.0322075 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0319627 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0318824 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0317362 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0313115 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0311409 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0307639 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0304892 |
| NUP58 | nucleoporin 58 | 0.0301365 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0299435 |
| INSIG2 | insulin induced gene 2 | 0.0298048 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0297175 |
| WDR45B | WD repeat domain 45B | 0.0294024 |
| ETNK1 | ethanolamine kinase 1 | 0.0290442 |
| COPA | coatomer protein complex, subunit alpha | 0.0289403 |
| DOCK5 | dedicator of cytokinesis 5 | 0.02823 |
| VIM | vimentin | 0.028019 |
| RLF | rearranged L-myc fusion | 0.0279338 |
| SPAG9 | sperm associated antigen 9 | 0.0279288 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0278228 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.027735 |
| NEK7 | NIMA-related kinase 7 | 0.0277208 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0275586 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0275309 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0274711 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0272308 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0271433 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0270601 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0268841 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.026784 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0266962 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0265174 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0261277 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0257973 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0255199 |
| RBM39 | RNA binding motif protein 39 | 0.0253217 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.025214 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0250382 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0250232 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0249157 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0248906 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0248254 |
| FMNL2 | formin-like 2 | 0.024807 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0247801 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0245512 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0244672 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0242103 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0239348 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0239124 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0238104 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0237357 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0237224 |
| NOP58 | NOP58 ribonucleoprotein | 0.0236859 |
| TPR | translocated promoter region, nuclear basket protein | 0.0235322 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.02348 |
| ZNF638 | zinc finger protein 638 | 0.023397 |
| TPM3 | tropomyosin 3 | 0.0233739 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0229835 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.277964 |
| FN1 | fibronectin 1 | -0.261959 |
| NRG1 | neuregulin 1 | -0.23934 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.195717 |
| EXT1 | exostosin glycosyltransferase 1 | -0.11298 |
| HMGA2 | high mobility group AT-hook 2 | -0.100961 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0928391 |
| ASPH | aspartate beta-hydroxylase | -0.083609 |
| SYT1 | synaptotagmin I | -0.0756069 |
| GLIS3 | GLIS family zinc finger 3 | -0.0673646 |
| VCL | vinculin | -0.0663486 |
| FTL | ferritin, light polypeptide | -0.0619041 |
| NRP1 | neuropilin 1 | -0.0618138 |
| NTN4 | netrin 4 | -0.0546153 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0544892 |
| TMEM156 | transmembrane protein 156 | -0.0522638 |
| TMSB10 | thymosin beta 10 | -0.0521465 |
| MAP1B | microtubule-associated protein 1B | -0.0518194 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0514893 |
| HLA-B | major histocompatibility complex, class I, B | -0.0491105 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.04561 |
| EGR1 | early growth response 1 | -0.0452285 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0449231 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0422302 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.039041 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0367706 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0364779 |
| KLHL5 | kelch-like family member 5 | -0.0362812 |
| AEBP2 | AE binding protein 2 | -0.0362005 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0360293 |
| ETV1 | ets variant 1 | -0.0356942 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0355787 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0354983 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0350978 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0350186 |
| OSMR | oncostatin M receptor | -0.0346691 |
| RAI14 | retinoic acid induced 14 | -0.0337792 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0333585 |
| ITGA1 | integrin, alpha 1 | -0.0327008 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0326249 |
| PALLD | palladin, cytoskeletal associated protein | -0.0324725 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.032372 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.031996 |
| RASAL2 | RAS protein activator like 2 | -0.0319703 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0307075 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0294253 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0293537 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0290885 |
| EFNA5 | ephrin-A5 | -0.0283725 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0282854 |
| POTEF | POTE ankyrin domain family, member F | -0.028225 |
| ACTG1 | actin gamma 1 | -0.0278739 |
| LMNA | lamin A/C | -0.0274231 |
| RANBP17 | RAN binding protein 17 | -0.0273625 |
| RNF213 | ring finger protein 213 | -0.0267503 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0266571 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0263393 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0261993 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0260911 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0255353 |
| SLC35F3 | solute carrier family 35, member F3 | -0.024934 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0248352 |
| NXN | nucleoredoxin | -0.0247503 |
| STC2 | stanniocalcin 2 | -0.0246367 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0244565 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0242556 |
| MX2 | MX dynamin-like GTPase 2 | -0.0240084 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0235736 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0234084 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0233492 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.023093 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0230215 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0228272 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.022743 |
| SEPTIN9 | septin 9 | -0.0226849 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0224415 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0218969 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0217777 |
| NBEA | neurobeachin | -0.0216561 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0216246 |
| RAB31 | RAB31, member RAS oncogene family | -0.0215289 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.021362 |
| IFI44L | interferon-induced protein 44-like | -0.0210857 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0210366 |
| FOXP1 | forkhead box P1 | -0.0209672 |
| FUS | FUS RNA binding protein | -0.0208089 |
| PRKCA | protein kinase C, alpha | -0.0207209 |
| GPATCH2L | G patch domain containing 2-like | -0.0206922 |
| TNS3 | tensin 3 | -0.0206632 |
| ITGB5 | integrin, beta 5 | -0.0206572 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0205316 |
| TENM4 | teneurin transmembrane protein 4 | -0.0205216 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0202879 |
| ATF6 | activating transcription factor 6 | -0.0202455 |
| RIGI | RNA sensor RIG-I | -0.0201885 |
| GLUL | glutamate-ammonia ligase | -0.0197731 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0197647 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0197302 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0197133 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0196522 |
